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Association between retinal vein occlusion and an increased risk of acute myocardial infarction: A nationwide population-based follow-up study

. Author Contributions Conceptualization: Yu-Yen Chen, Shwu-Jiuan Sheu, Dachen Chu, Pesus Chou. Formal analysis: Yu-Yen Chen, Shwu-Jiuan Sheu, Hsiao-Yun Hu, Pesus Chou. Investigation: Yu-Yen Chen ... . Methodology: Yu-Yen Chen, Shwu-Jiuan Sheu, Hsiao-Yun Hu, Dachen Chu, Pesus Chou. Validation: Yu-Yen Chen, Shwu-Jiuan Sheu, Hsiao-Yun Hu, Dachen Chu, Pesus Chou. Writing ± original draft: Yu-Yen Chen, Pesus Chou

Differential autophagic effects of vital dyes in retinal pigment epithelial ARPE-19 and photoreceptor 661W cells

Indocyanine green (ICG) and brilliant blue G (BBG) are commonly used vital dyes to remove internal limiting membrane (ILM) in vitreoretinal surgery. The vital dyes have shown cytotoxic effects in ocular cells. Autophagy is a stress responsive pathway for either protecting cells or promoting cell death. However, the role of autophagy in ocular cells in response to the vital dyes ...

Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety

Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated. Adenovirus is an attractive gene vector as it can deliver large genes and allow for short-term gene expression, but how safe it is when ...

Ocular sarcoidosis and tuberculous lymphadenopathy: coincidence or real association

Tuberculosis and sarcoidosis share similarity in histopathologic findings and clinically occur in association with each other occasionally. Tuberculosis should always be ruled out before the diagnosis of sarcoidosis. But, the diagnosis is often complicated, especially in extrapulmonary cases. Here we present a case of bilateral vitreous hemorrhage with uveitis. Ocular sarcoidosis ...

Reversible alopecia in Vogt-Koyanagi-Harada disease and sympathetic ophthalmia

Background Vogt-Koyanagi-Harada (VKH) disease and sympathetic ophthalmia (SO) are both autoimmune disorders targeting melanin-bearing cells, even though their etiologies are different. Both shared many ocular and systemic manifestations, including integumentary findings. Most of the literature focused on the ocular manifestations and related treatment. Alopecia was seldom ...