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23 papers found.
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Effect of religion on hypertension in adult Buddhists and residents in China: A cross-sectional study

information AffiliationsDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, ChinaQingtao Meng, Ying Xu, Rufeng Shi, Xin Zhang, Si Wang, Kai Liu & Xiaoping Chen AuthorsSearch for ... • Google Scholar Search for Xin Zhang in:Nature Research journals • PubMed • Google Scholar Search for Si Wang in:Nature Research journals • PubMed • Google Scholar Search for Kai Liu in:Nature Research

Mitigation of severe urban haze pollution by a precision air pollution control approach

Severe and persistent haze pollution involving fine particulate matter (PM2.5) concentrations reaching unprecedentedly high levels across many cities in China poses a serious threat to human health. Although mandatory temporary cessation of most urban and surrounding emission sources is an effective, but costly, short-term measure to abate air pollution, development of long-term...

Downregulation of Thromboxane A2 Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery

Thromboxane A2 (TXA2) acts on TXA2 receptors (TP) to regulate renal artery blood flow and subsequently contributes to the pathogenesis of renal ischemia. The present study was designed to examine if nuclear factor-kappaB (NF-κB) signaling pathway is involved in the downregulation of TP receptors in rat renal artery. Rat renal artery segments were organ cultured for 6 or 24 h...

Prognostic Value of Overexpressed p16INK4a in Vulvar Cancer: A Meta-Analysis

specimens. Data extraction Three investigators (Hanyu Cao, Si Wang, and Zhenyu Zhang) extracted independently all articles complying with the aforementioned inclusion criteria. Any discrepancy was resolved

Minor defects of the luminal integrity in arterial introducer eSheaths after transcatheter aortic valve implantation

Background Medical devices such as implant delivery systems are commonly used during minimally invasive procedures in the cardiovascular system. These devices often have lubricious polymer coatings to reduce friction between the device and blood vessels but coatings may separate and potentially cause serious injuries to patients. Methods Lubricious coated eSheaths for...

Analysis of Pvama1 genes from China-Myanmar border reveals little regional genetic differentiation of Plasmodium vivax populations

Background With the premise of diminishing parasite genetic diversity following the reduction of malaria incidence, the analysis of polymorphic antigenic markers may provide important information about the impact of malaria control on local parasite populations. Here we evaluated the genetic diversity of Plasmodium vivax apical membrane antigen 1 (Pvama1) gene in a parasite...

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs

WITH ETHICS GUIDELINES Lixia Wang, Fei Yi, Lina Fu, Jiping Yang, Si Wang, Zhaoxia Wang, Keiichiro Suzuki, Liang Sun, Xiuling Xu, Yang Yu, Jie Qiao, Juan Carlos Izpisua Belmonte, Ze Yang, Yun Yuan, Jing

Elevated resting heart rate predisposes metabolic syndrome in women rather than in men: a 15-year prospective study

Background Increasing evidences have indicated that there are gender differences in the prevalence of metabolic syndrome(MS), but the mechanism is uncertain. Methods A total of 711 subjects aged 35–65 years accepted health examinations both in 1992 and 2007. Since 114 subjects had MS and 7 had heart disease at baseline, they were excluded from the analysis. Therefore, 590...

Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies

Background: It has been proposed that night shift work could increase breast cancer incidence. A 2007 World Health Organization review concluded, mainly from animal evidence, that shift work involving circadian disruption is probably carcinogenic to humans. We therefore aimed to generate prospective epidemiological evidence on night shift work and breast cancer incidence. Methods...

Mesenchymal Stem Cells Stabilize Atherosclerotic Vulnerable Plaque by Anti-Inflammatory Properties

Background and objectives Formation and progression of atherosclerotic vulnerable plaque (VP) is the primary cause of many cardio-cerebrovascular diseases such as acute coronary syndrome and stroke. It has been reported that bone marrow mesenchymal stem cells (MSC) exhibit protective effects against many kinds of diseases including myocardial infarction. Here, we examined the...

Dihydrochalcone glycosides from Oxytropis myriophylla

Gaimei She 0 Si Wang 0 Bin Liu 0 0 School of Chinese Pharmacy, Beijing University of Chinese Medicine , Beijing, People's Republic of China Chemical investigations of the 70% alcohol extract of

First-Morning Urinary Melatonin and Breast Cancer Risk in the Guernsey Study

Xiao-Si Wang Sarah Tipper Paul N. Appleby Naomi E. Allen Timothy J. Key Ruth C. Travis ) It has been hypothesized that suppressed nocturnal melatonin production is associated with an increased risk ... ). ACKNOWLEDGMENTS Author affiliations: Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom (Naomi E. Allen, Paul N. Appleby, Timothy J. Key, Sarah Tipper, Ruth C. Travis, Xiao-Si Wang); and

Kaiso Interacts with p120-Catenin to Regulate β-Catenin Expression at the Transcriptional Level

Background We have reported that p120-catenin could regulate β-catenin transcription in lung cancer cells, but the specific mechanism is unclear. Methods and Results In this study, bisulfite sequencing PCR showed that the β-catenin promoter region in SPC-A-1 and LTEP-a-2 lung cancer cell lines has Kaiso binding sites sequences and CpG islands which may combine with Kaiso. The...

Extending an In Vitro Panel for Estrogenicity Testing: The Added Value of Bioassays for Measuring Antiandrogenic Activities and Effects on Steroidogenesis

In the present study, a previously established integrated testing strategy (ITS) for in vitro estrogenicity testing was extended with additional in vitro assays in order to broaden its sensitivity to different modes of action resulting in apparent estrogenicity, i.e., other than estrogen receptor (ER) binding. To this end, an extra set of 10 estrogenic compounds with modes of...

Over Time, Do Anthropometric Measures Still Predict Diabetes Incidence in Chinese Han Nationality Population from Chengdu Community?

Si Wang, and Xiaoping Chen Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, China Received 20 June 2013; Revised 3 September 2013; Accepted 11 September

Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

pigmentosum. COMPLIANCE WITH ETHICS GUIDELINES Lina Fu, Xiuling Xu, Ruotong Ren, Jun Wu, Weiqi Zhang, Jiping Yang, Xiaoqing Ren, Si Wang, Yang Zhao, Liang Sun, Yang Yu, Zhaoxia Wang, Ze Yang, Yun Yuan, Jie