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Search: authors:"Simon R. Cox"

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Brain cortical characteristics of lifetime cognitive ageing

, UK 1 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh , 7 George Square, Edinburgh EH8 9JZ , UK 2 & Simon R. Cox 3 Division of Psychiatry, University of Edinburgh

Risk and protective factors for structural brain ageing in the eighth decade of life

Individuals differ markedly in brain structure, and in how this structure degenerates during ageing. In a large sample of human participants (baseline n = 731 at age 73 years; follow-up n = 488 at age 76 years), we estimated the magnitude of mean change and variability in changes in MRI measures of brain macrostructure (grey matter, white matter, and white matter hyperintensity ...