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IL-25-induced activation of nasal fibroblast and its association with the remodeling of chronic rhinosinusitis with nasal polyposis

. Conceptualization: Soo-Kyoung Park, Ki-Sang Rha, Yong-Min Kim. Data curation: Soo-Kyoung Park, Yong-De Jin, Yeong-Kyu Park, Sun-Hee Yeon, Yong-Min Kim. Formal analysis: Soo-Kyoung Park, Yong-De Jin, Sun-Hee Yeon ... . Investigation: Sun-Hee Yeon, Ki-Sang Rha, Yong-Min Kim. Methodology: Sun-Hee Yeon, Jun Xu. Project administration: Soo-Kyoung Park, Yong-De Jin, Yeong-Kyu Park, Ki-Sang Rha, Yong-Min Kim. Resources: Sun-Hee

Suppression of Adipocyte Differentiation by Foenumoside B from Lysimachia foenum-graecum Is Mediated by PPARĪ³ Antagonism

Lysimachia foenum-graecum extract (LFE) and its active component foenumoside B (FSB) have been shown to inhibit adipocyte differentiation, but their mechanisms were poorly defined. Here, we investigated the molecular mechanisms responsible for their anti-adipogenic effects. Both LFE and FSB inhibited the differentiation of 3T3-L1 preadipocytes induced by peroxisome proliferator...