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Search: authors:"Stephanie A. Bien"

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Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

Department of Genetics, Rutgers University , Piscataway, NJ , USA 7 Stephanie A. Bien 8 Epidemiology Program, University of Hawaii Cancer Center , Honolulu, HI , USA 9 Department of Medicine, Institute for

Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array

Investigating genetic architecture of complex traits in ancestrally diverse populations is imperative to understand the etiology of disease. However, the current paucity of genetic research in people of African and Latin American ancestry, Hispanic and indigenous peoples in the United States is likely to exacerbate existing health disparities for many common diseases. The ...

Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can facilitate detection of functional candidates and additional independent risk variants. We analyzed 11,900 cases and 14,311 controls in ...