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4 papers found.
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A Call To Cyberarms: The International Arbitrator’s Duty To Avoid Digital Intrusion

INTRUSION Stephanie Cohen* & Mark Morril** I. Introduction ............................................................................. 982  II. Data Security Threats in International Arbitration ... ................................................... 1006  E. Bounded by Reasonableness ............................................ 1009  V. Implementing the Duty to Avoid Intrusion.......................... 1012  * Stephanie Cohen is a Canadian

Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification

Background Spatial heterogeneity in biomarker expression may impact breast cancer classification. The aims of this study were to estimate the frequency of spatial heterogeneity in biomarker expression within tumors, to identify technical and biological factors contributing to spatial heterogeneity, and to examine the impact of discordant biomarker status within tumors on clinical...

Early Experiences Implementing Pre-exposure Prophylaxis (PrEP) for HIV Prevention in San Francisco

Albert Liu and colleagues report early experiences with uptake and delivery of pre-exposure prophylaxis(PrEP)for HIV prevention in three different settings in San Francisco. PrEP can be an important component of a comprehensive HIV prevention program and can complement efforts to increase HIV testing, linkage to care, and early initiation of antiretroviral therapy. Please see...

The prevalence of BRCA1 mutations among young women with triple-negative breast cancer

Background Molecular screening for BRCA1 and BRCA2 mutations is now an established component of risk evaluation and management of familial breast cancer. Features of hereditary breast cancer include an early age-of-onset and over-representation of the 'triple-negative' phenotype (negative for estrogen-receptor, progesterone-receptor and HER2). The decision to offer genetic...