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Search: authors:"Stephen Gire"

3 papers found.
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In vivo Ebola virus infection leads to a strong innate response in circulating immune cells

Background Ebola virus is the causative agent of a severe syndrome in humans with a fatality rate that can approach 90 %. During infection, the host immune response is thought to become dysregulated, but the mechanisms through which this happens are not entirely understood. In this study, we analyze RNA sequencing data to determine the host response to Ebola virus infection in ...

High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic

BMC Genomics Rachel Sealfon Stephen Gire Crystal Ellis Stephen Calderwood Firdausi Qadri Lisa Hensley Manolis Kellis Edward T Ryan Regina C LaRocque Jason B Harris Pardis C Sabeti Sealfon et al

Molecular Diagnostics for Lassa Fever at Irrua Specialist Teaching Hospital, Nigeria: Lessons Learnt from Two Years of Laboratory Operation

Background Lassa fever is a viral hemorrhagic fever endemic in West Africa. However, none of the hospitals in the endemic areas of Nigeria has the capacity to perform Lassa virus diagnostics. Case identification and management solely relies on non-specific clinical criteria. The Irrua Specialist Teaching Hospital (ISTH) in the central senatorial district of Edo State struggled with ...