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Mitochondrial dysfunction reduces yeast replicative lifespan by elevating RAS-dependent ROS production by the ER-localized NADPH oxidase Yno1

) funded by the Ministry of Education, Science and Technology, Republic of Korea. 14 / 18 Author Contributions Conceptualization: Dae-Gwan Yi, Won-Ki Huh. Data curation: Dae-Gwan Yi, Sujin Hong. Formal ... analysis: Dae-Gwan Yi, Sujin Hong. Funding acquisition: Won-Ki Huh. Investigation: Dae-Gwan Yi, Sujin Hong, Won-Ki Huh. Methodology: Dae-Gwan Yi, Sujin Hong. Project administration: Won-Ki Huh. Resources