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Digital informal learning among Chinese university students: the effects of digital competence and personal factors

international research projects and cooperation projects, including VLIR-UOS projects and Erasmus Mundus projects supported by the European Commission. Tao He is a Ph.D researcher working at the Department of ... He Chang Zhu Although informal learning with digital technology is a near universal activity among university students, the processes that influence and regulate digital informal learning (DIL) is

Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth

Background ZNF331 was reported to be a transcriptional repressor. Methylation of the promoter region of ZNF331 has been found frequently in human esophageal and gastric cancers. The function and methylation status of ZNF331 remain to be elucidated in human colorectal cancer (CRC). Methods Six colorectal cancer cell lines, 146 cases of primary colorectal cancer samples, and 10...

Proteomic comparison by iTRAQ combined with mass spectrometry of egg white proteins in laying hens (Gallus gallus) fed with soybean meal and cottonseed meal

Conceptualization: Tao He, Guanghai Qi. Data curation: Tao He, Haijun Zhang, Jing Wang. Formal analysis: Tao He, Haijun Zhang, Hongyuan Yue. Investigation: Shugeng Wu, Hongyuan Yue. Methodology: Tao He, Haijun ... Zhang, Guanghai Qi. Project administration: Shugeng Wu, Guanghai Qi. Software: Tao He, Jing Wang. Supervision: Shugeng Wu, Guanghai Qi. Validation: Tao He. Writing ± original draft: Tao He. Writing

The effects of immune protein CD3ζ development and degeneration of retinal neurons after optic nerve injury

Major histocompatibility complex (MHC) class I molecules and their receptors play fundamental roles in neuronal death during diseases. T-cell receptors (TCR) function as MHCI receptor on T-cells and both MHCI and a key component of TCR, CD3ζ, are expressed by mouse retinal ganglion cells (RGCs) and displaced amacrine cells. Mutation of these molecules compromises the development...

The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells

Bone cancer pain (BCP) severely compromises the quality of life, while current treatments are still unsatisfactory. Here, we tested the antinociceptive effects of triptolide (T10), a substance with considerable anti-tumor efficacies on BCP, and investigated the underlying mechanisms targeting the spinal dorsal horn (SDH). Intratibial inoculation of Walker 256 mammary gland...

Influences of age-related changes in mesenchymal stem cells on macrophages during in-vitro culture

Background Mesenchymal stem cells (MSCs) have been widely used in cytotherapy and tissue engineering due to their immunosuppressive ability and regenerative potential. Recently, the immunomodulatory influence of MSCs has been gaining increasing attention because their functional roles in modulating immune responses likely have high clinical significance. Methods In this study, we...

Unilateral global interval bifurcation theorem for periodic p-Laplacian and its applications

In this paper, we establish a unilateral global bifurcation result from interval for a class of periodic p-Laplacian problems with non-differentiable nonlinearity. By applying the above result, we shall prove the existence of the principal half-eigenvalues for the half-quasilinear periodic p-Laplacian problem − ( φ p ( x ′ ) ) ′ + q ( t ) φ p ( x ) = λ a ( t ) φ p ( x ) + α ( t...

Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis

Background DIRAS1 is a new member of the Ras gene family. It was described as a potential tumor suppressor in human glioblastomas and esophageal cancer. The role of DIRAS1 in colorectal cancer remains unclear. Methods To explore the epigenetic changes and function of DIRAS1 in human colorectal cancer, we studied ten colorectal cancer cell lines and 146 primary colorectal cancer...

Predictive remapping gives rise to environmental inhibition of return

Neurons in various brain regions predictively respond to stimuli that will be brought to their receptive fields by an impending eye movement. This neural mechanism, known as predictive remapping, has been suggested to underlie spatial constancy. Inhibition of return (IOR) is a bias against recently attended locations. The present study examined whether predictive remapping is a...

Distribution, attribution, and radiative forcing of snow cover changes over China from 1982 to 2013

Unlike large-scale snow cover variation and its effects on the Earth’s climate system, regional-scale snow cover and its impacts on surface–atmosphere interaction and the Earth’s energy budget have received little attention. This study aims to quantify the distribution and attribution of snow cover changes over mainland China and the associated snow radiative forcing from 1982 to...

Inhibitory cueing effects following manual and saccadic responses to arrow cues

With two cueing tasks, in the present study we examined output-based inhibitory cueing effects (ICEs) with manual responses to arrow targets following manual or saccadic responses to arrow cues. In all experiments, ICEs were observed when manual localization responses were required to both the cues and targets, but only when the cue–target onset asynchrony (CTOA) was 2,000 ms or...

Higher BNP levels within physiological range correlate with beneficial nonfasting lipid profiles in the elderly: a cross-sectional study

Background Emerging studies indicate that B-type natriuretic peptide (BNP), a well-known biomarker for heart failure, also plays pivotal roles in metabolic control. Circulating BNP levels progressively increase as ages grow older. However, the association between BNP levels and lipid metabolism in the elderly remains unknown. Methods A total of 680 eligible volunteers (male...

Why is greater medication adherence associated with better outcomes

Background Previous studies found an association of greater adherence to placebo medication with better outcomes. The present study tested whether this association was explained by any of the following factors: 1) adherence to other medications, 2) healthcare behaviors, 3) disease risk, or 4) predicted degree of adherence. Data included information on more than 800 risk factors...

Photoreduction of carbon dioxide using strontium zirconate nanoparticles

in the Institute of Chemical Sciences Bahauddin Zakariya University, Multan, Pakistan. His research interests include photocatalysis, magnetic nanomaterials and nanocomposites. Tao He was born in 1971

Bifurcation from interval and positive solutions for a class of fourth-order two-point boundary value problem

We consider the fourth-order two-point boundary value problem x ′′′′ + k x ″ + l x = f ( t , x ) , 0 < t < 1 , x ( 0 ) = x ( 1 ) = x ′ ( 0 ) = x ′ ( 1 ) = 0 , which is not necessarily linearizable. We give conditions on the parameters k, l and f ( t , x ) that guarantee the existence of positive solutions. The proof of our main result is based upon topological degree theory and...

Weak cation exchange magnetic beads coupled with matrix-assisted laser desorption ionization-time of flight-mass spectrometry in screening serum protein markers in osteopenia

The present study aimed at investigating the weak cation magnetic separation technology and matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) in screening serum protein markers of osteopenia from ten postmenopausal women and ten postmenopausal women without osteopenia as control group, to find a new method for screening biomarkers and...

Nestin Positive Bone Marrow Derived Cells Responded to Injury Mobilize into Peripheral Circulation and Participate in Skin Defect Healing

Exogenously infused mesenchymal stem cells (MSCs) are thought to migrate to injury site through peripheral blood stream and participate in tissue repair. However, whether and how endogenous bone marrow MSCs mobilized to circulating and targeted to tissue injury has raised some controversy, and related studies were restricted by the difficulty of MSCs identifying in vivo. Nestin...

The effects of smoking and drinking on all-cause mortality in patients with dilated cardiomyopathy: a single-center cohort study

Subject Recent studies have shown that smoking and drinking are associated with poorer outcomes in patients with cardiomyopathy. The purpose of this study was to determine all-cause mortality in dilated cardiomyopathy (DCM) associated with smoking and drinking. Methods An observational cohort study was undertaken in DCM patients from November 2003 to September 2011. A total of...