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35 papers found.
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Smoking is not associated with higher prevalence of JC virus in MS patients

John Cunningham virus (JCV) causes rare, but potentially life-threatening progressive multifocal leukoencephalopathy (PML) in natalizumab-treated multiple sclerosis (MS) patients. Beside JCV index, there is currently no other factor for further risk stratification. Because smoking was reported as potential risk factor for several viral and bacterial infections, we aimed to...

Computer und Psychotherapie – geht das zusammen?

Die Verbreitung moderner Medien wirkt sich zunehmend auf psychologische Behandlungsangebote aus. Während die empirische Basis internetbasierter Interventionen zur Behandlung häufiger psychischer Beeinträchtigungen wächst und ihre Anwendung in der Regelversorgung gegenwärtig international erprobt wird, bestehen zusätzliche Bestrebungen, das gewonnene Knowhow mit konventioneller...

An internet-based self-help intervention for older adults after marital bereavement, separation or divorce: study protocol for a randomized controlled trial

0 Thomas Berger 0 Hans Joerg Znoj 0 0 Department of Psychology, University of Bern , Fabrikstrasse 8, 3012 Bern , Switzerland Background: Marital bereavement and separation or divorce are among the

Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination

Antibodies to the myelin oligodendrocyte glycoprotein (MOG) are associated with a subset of inflammatory demyelinating diseases of the central nervous system such as acute disseminated encephalomyelitis and neuromyelitis optica spectrum disorders. However, whether human MOG antibodies are pathogenic or an epiphenomenon is still not completely clear. Although MOG is highly...

Cerebrospinal fluid B cells and disease progression in multiple sclerosis - A longitudinal prospective study

excellent technical assistance. Author Contributions Conceptualization: Sebastian Wurth, Markus Reindl, Thomas Berger. Data curation: Sebastian Wurth, Markus Reindl, Thomas Berger. Formal analysis ... : Sebastian Wurth, Markus Reindl, Thomas Berger. Funding acquisition: Markus Reindl, Thomas Berger. Investigation: Sebastian Wurth, Bettina Kuenz, Gabriel Bsteh, Rainer Ehling, Franziska Di Pauli, Harald

Paroxysmal and unusual symptoms as first clinical manifestation of multiple sclerosis do not indicate benign prognosis—The PaSiMS II study

Ehling, Lisa-Maria Walchhofer, Michaela Wagner. Methodology: Gabriel Bsteh, Rainer Ehling, Harald Hegen, Markus Reindl, Thomas Berger. Software: Gabriel Bsteh. Supervision: Markus Reindl, Florian ... Deisenhammer, Thomas Berger. Validation: Gabriel Bsteh, Thomas Berger. Visualization: Gabriel Bsteh. Writing ± original draft: Gabriel Bsteh, Rainer Ehling. Writing ± review & editing: Lisa-Maria Walchhofer

Stability and predictive value of anti-JCV antibody index in multiple sclerosis: A 6-year longitudinal study

multiple sclerosis: Biogen, Merck, Novartis, ratiopharm, Roche, Sanofi Aventis, and TEVA. Thomas Berger and his institution have received financial support by unrestricted research grants and clinical trial

Can preferential credit programs speed up the adoption of low-carbon agricultural systems in Mato Grosso, Brazil? Results from bioeconomic microsimulation

by 2020 (World Bank 2010, 2011; Mozzer Matthias Siebold Thomas Berger 2012). However, this should not undermine the sector’s great economic and political importance, earning around 52% of the total

Web-based stress management for newly diagnosed cancer patients (STREAM-1): a randomized, wait-list controlled intervention study

Background Being diagnosed with cancer causes major psychological distress, yet the majority of newly diagnosed cancer patients lack psychological support. Internet interventions overcome many barriers for seeking face-to-face support and allow for independence in time and place. We assess efficacy and feasibility of the first web-based stress management intervention (STREAM...

Internet-based treatment for Romanian adults with panic disorder: protocol of a randomized controlled trial comparing a Skype-guided with an unguided self-help intervention (the PAXPD study)

Background Efficacy of self-help internet-based cognitive behavior therapy (ICBT) for anxiety disorders has been confirmed in several randomized controlled trials. However, the amount and type of therapist guidance needed in ICBT are still under debate. Previous studies have shown divergent results regarding the role of therapist guidance and its impact on treatment outcome. This...

Alemtuzumab Use in Clinical Practice: Recommendations from European Multiple Sclerosis Experts

funded by Sanofi Genzyme. All advisors received honoraria payments for their participation. Open access fee was funded by the Medical University of Innsbruck. Conflict of interest Thomas Berger has

Long Term Clinical Prognostic Factors in Relapsing-Remitting Multiple Sclerosis: Insights from a 10-Year Observational Study

Background Multiple sclerosis (MS) has a highly heterogenic course making prediction of long term outcome very difficult. Objective The objective was to evaluate current and identify additional clinical factors that are linked to long term outcome of relapsing-remitting MS assessed by disability status 10 years after disease onset. Methods This observational study included 793...

Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging

In multiple sclerosis (MS), iron accumulates inside activated microglia/macrophages at edges of some chronic demyelinated lesions, forming rims. In susceptibility-based magnetic resonance imaging at 7 T, iron-laden microglia/macrophages induce a rim of decreased signal at lesion edges and have been associated with slowly expanding lesions. We aimed to determine (1) what lesion...

Internet-based individually versus group guided self-help treatment for social anxiety disorder: protocol of a randomized controlled trial

Ava Schulz 0 Timo Stolz 0 Thomas Berger 0 0 Department of Clinical Psychology and Psychotherapy, University of Bern , Bern , Switzerland Background: Social anxiety disorder (SAD) is one of the most

Psychotherapy integration under scrutiny: investigating the impact of integrating emotion-focused components into a CBT-based approach: a study protocol of a randomized controlled trial

Background This currently recruiting randomized controlled trial investigates the effects of integrating components of Emotion-Focused Therapy (EFT) into Psychological Therapy (PT), an integrative form of cognitive-behavioral therapy in a manner that is directly mirroring common integrative practice in the sense of assimilative integration. Aims of the study are to understand how...

Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders

Background The discovery of a highly specific antibody against the aquaporin-4 (AQP4) water channel (AQP4-IgG) unified the spectrum of neuromyelitis optica spectrum disorders (NMOSD), which are considered to be antibody-mediated autoimmune diseases. The AQP4 water channel is located on astrocytic end-feet processes and consists of six transmembrane helical domains forming three...

The Role of Pulse Shape in Motor Cortex Transcranial Magnetic Stimulation Using Full-Sine Stimuli

A full-sine (biphasic) pulse waveform is most commonly used for repetitive transcranial magnetic stimulation (TMS), but little is known about how variations in duration or amplitude of distinct pulse segments influence the effectiveness of a single TMS pulse to elicit a corticomotor response. Using a novel TMS device, we systematically varied the configuration of full-sine pulses...

The InterHerz project - a web-based psychological treatment for cardiac patients with depression: study protocol of a randomized controlled trial

Berger 0 0 Department of Clinical Psychology and Psychotherapy, University of Bern , Gesellschaftsstrasse 49, Bern 3012 , Switzerland 1 Institute of Social and Preventive Medicine (ISPM), University of

Evaluating an e-mental health program (“deprexis”) as adjunctive treatment tool in psychotherapy for depression: design of a pragmatic randomized controlled trial

Background Major depressive disorder (MDD) places a significant disease burden on individuals as well as on societies. Several web-based interventions for MDD have shown to be effective in reducing depressive symptoms. However, it is not known whether web-based interventions, when used as adjunctive treatment tools to regular psychotherapy, have an additional effect compared to...