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32 papers found.
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Short-term Impact of Mass Drug Administration With Dihydroartemisinin Plus Piperaquine on Malaria in Southern Province Zambia: A Cluster-Randomized Controlled Trial

Background. Mass drug administration (MDA) using dihydroartemisinin plus piperaquine (DHAp) represents a potential strategy to clear Plasmodium falciparum infections and reduce the human parasite reservoir. Methods. A cluster-randomized controlled trial in Southern Province, Zambia, was used to assess the short-term impact of 2 rounds of community-wide MDA and household-level ...

Community Coverage with Insecticide-Treated Mosquito Nets and Observed Associations with All-Cause Child Mortality and Malaria Parasite Infections

, E-mail: bennetta2@globalhealth.ucsf .edu. Joshua Yukich, Joseph Keating, and Thomas P. Eisele, Center for Applied Malaria Research and Evaluation, Tulane School of Public Health and Tropical Medicine

Costs and cost-effectiveness of a large-scale mass testing and treatment intervention for malaria in Southern Province, Zambia

Hamainza Adam Bennett Duncan Earle Mulakwa Kamuliwo Richard W Steketee Thomas P Eisele 0 John M Miller 0 Center for Applied Malaria Research and Evaluation, Tulane University School of Public Health and

Population-Wide Malaria Testing and Treatment with Rapid Diagnostic Tests and Artemether-Lumefantrine in Southern Zambia: A Community Randomized Step-Wedge Control Trial Design

-mails: , , , and . Busiku Hamainza, National Malaria Control Programme, Zambia Ministry of Health, Lusaka, Zambia, E-mail: . Joshua O. Yukich, Joseph Keating, and Thomas P. Eisele, Center for Applied

A qualitative study of perceptions of a mass test and treat campaign in Southern Zambia and potential barriers to effectiveness

Background A mass test and treat campaign (MTAT) using rapid diagnostic tests (RDTs) and artemether-lumefantrine (AL) was conducted in Southern Zambia in 2012 and 2013 to reduce the parasite reservoir and progress towards malaria elimination. Through this intervention, community health workers (CHWs) tested all household members with rapid diagnostic tests (RDTs) and provided ...

Coverage and system efficiencies of insecticide-treated nets in Africa from 2000 to 2017

L Moyes Andrew J Tatem Michael Lynch Cristin A Fergus Joshua Yukich Adam Bennett Thomas P Eisele Jan Kolaczinski Richard E Cibulskis Simon I Hay Peter W Gething - Stay current on the latest in life ... . Weiss, Bonnie Mappin, Ursula Dalrymple, Ewan Cameron, Donal Bisanzio, David L. Smith, Catherine L. Moyes, Andrew J. Tatem, Michael Lynch, Cristin A. Fergus, Joshua Yukich, Adam Bennett, Thomas P. Eisele

African Malaria Control Programs Deliver ITNs and Achieve What the Clinical Trials Predicted

Thomas Eisele and Richard Steketee discuss new research in PLoS Medicine by Stephen Lim and colleagues that examined the association of insecticide-treated nets with the reduction of P. falciparum prevalence in children under 5 and all-cause post-neonatal mortality.

Declining malaria in Africa: improving the measurement of progress

The dramatic escalation of malaria control activities in Africa since the year 2000 has increased the importance of accurate measurements of impact on malaria epidemiology and burden. This study presents a systematic review of the emerging published evidence base on trends in malaria risk in Africa and argues that more systematic, timely, and empirically-based approaches are ...

Claims about the Misuse of Insecticide-Treated Mosquito Nets: Are These Evidence-Based?

Thomas Eisele and colleagues dispute reports in the media and elsewhere that insecticide-treated nets are not widely used, or are misused, and say that such misconceptions are not evidence-based and are damaging to malaria control efforts.

Planning long lasting insecticide treated net campaigns: should households’ existing nets be taken into account?

Background Mass distribution of long-lasting insecticide treated bed nets (LLINs) has led to large increases in LLIN coverage in many African countries. As LLIN ownership levels increase, planners of future mass distributions face the challenge of deciding whether to ignore the nets already owned by households or to take these into account and attempt to target individuals or ...

Measuring Coverage in MNCH: Accuracy of Measuring Diagnosis and Treatment of Childhood Malaria from Household Surveys in Zambia

Background To assess progress in the scale-up of rapid diagnostic tests and artemisinin-based combination therapies (ACTs) across Africa, malaria control programs have increasingly relied on standardized national household surveys to determine the proportion of children with a fever in the past 2 wk who received an effective antimalarial within 1–2 d of the onset of fever. Here, ...

Travel history and malaria infection risk in a low-transmission setting in Ethiopia: a case control study

Background Malaria remains the leading communicable disease in Ethiopia, with around one million clinical cases of malaria reported annually. The country currently has plans for elimination for specific geographic areas of the country. Human movement may lead to the maintenance of reservoirs of infection, complicating attempts to eliminate malaria. Methods An unmatched case–control ...

Monitoring, characterization and control of chronic, symptomatic malaria infections in rural Zambia through monthly household visits by paid community health workers

Background Active, population-wide mass screening and treatment (MSAT) for chronic Plasmodium falciparum carriage to eliminate infectious reservoirs of malaria transmission have proven difficult to apply on large national scales through trained clinicians from central health authorities. Methodology Fourteen population clusters of approximately 1,000 residents centred around health ...

Measuring Coverage in MNCH: Total Survey Error and the Interpretation of Intervention Coverage Estimates from Household Surveys

In a PLOS Medicine Review, Thomas Eisele and colleagues discuss the importance of considering sampling and non-sampling errors when interpreting estimates of coverage of maternal, newborn, and child health interventions based on data from household surveys.

Is the Scale Up of Malaria Intervention Coverage Also Achieving Equity?

Background and Methods Malaria in Africa is most severe in young children and pregnant women, particularly in rural and poor households. In many countries, malaria intervention coverage rates have increased as a result of scale up; but this may mask limited coverage in these highest-risk populations. Reports were reviewed from nationally representative surveys in African ...

Protective efficacy of malaria case management for preventing malaria mortality in children: a systematic review for the Lives Saved Tool

Julie Thwing 0 Thomas P Eisele Richard W Steketee 0 Malaria Branch , Malaria Branch , Center for Global Health, Centers for Disease Control and Prevention , Atlanta GA , USA Background: The Lives

Comparison of Lives Saved Tool model child mortality estimates against measured data from vector control studies in sub-Saharan Africa

Friberg 1 Thomas P Eisele 0 0 Department of International Health and Development, Tulane University School of Public Health and Tropical Medicine , New Orleans, LA , USA 1 Department of International Health

Determinants of hanging and use of ITNs in the context of near universal coverage in Zambia

Roll Back Malaria recently recommended a policy of universal coverage with insecticide-treated nets (ITNs) so that all age groups can benefit from protection against malaria. Countries adopting the ‘universal access’ policy include Zambia. Policy implementation in many settings involves mass distribution of free ITNs to achieve a measure of universal coverage. This study examines ...

Household Possession and Use of Insecticide-Treated Mosquito Nets in Sierra Leone 6 Months after a National Mass-Distribution Campaign

Background In November 2010, Sierra Leone distributed over three million long-lasting insecticide-treated nets (LLINs) with the objective of providing protection from malaria to individuals in all households in the country. Methods We conducted a nationally representative survey six months after the mass distribution campaign to evaluate its impact on household insecticide-treated ...

Estimating Plasmodium falciparum Transmission Rates in Low-Endemic Settings Using a Combination of Community Prevalence and Health Facility Data

As some malaria control programs shift focus from disease control to transmission reduction, there is a need for transmission data to monitor progress. At lower levels of transmission, it becomes increasingly more difficult to measure precisely, for example through entomological studies. Many programs conduct regular cross sectional parasite prevalence surveys, and have access to ...