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Systematic reviews of health economic evaluations: a protocol for a systematic review of characteristics and methods applied

Edmund A. M. Neugebauer 3 4 Tim Mathes 0 0 Institute for Research in Operative Medicine, Witten/Herdecke University , Ostmerheimer Str. 200, Haus 38, 51109 Cologne , Germany 1 Faculty of Health

Interventions to increase adherence in patients taking immunosuppressive drugs after kidney transplantation: a systematic review of controlled trials

Immunosuppressive drugs have to be taken through the whole duration of kidney transplant survival to avoid rejection. Low adherence can increase the risk of allograft rejection. The objective was to evaluate the effectiveness of adherence-enhancing interventions (AEI) in kidney transplantation recipients taking immunosuppressive drugs. A search was performed in Medline, Embase, ...

Interventions to increase adherence in patients taking immunosuppressive drugs after kidney transplantation: a systematic review of controlled trials

Immunosuppressive drugs have to be taken through the whole duration of kidney transplant survival to avoid rejection. Low adherence can increase the risk of allograft rejection. The objective was to evaluate the effectiveness of adherence-enhancing interventions (AEI) in kidney transplantation recipients taking immunosuppressive drugs. A search was performed in Medline, Embase, ...

Relationship between surgeon volume and outcomes: a systematic review of systematic reviews

Background The surgeon volume-outcome relationship has been discussed for many years and its existence or nonexistence is of importance for various reasons. A lot of empirical work has been published on it. We aimed to summarize systematic reviews in order to present current evidence. Methods Medline, Embase, Cochrane database of systematic reviews (CDSR), and health technology ...

A systematic review of the impact of center volume in dialysis

Pieper et al. BMC Res Notes Dawid Pieper 0 Tim Mathes 0 Mark Roger Marshall 0 Institute for Research in Operative Medicine, Witten/Herdecke University , Ostmerheimer Str. 200, Building 38, 51109

Can AMSTAR also be applied to systematic reviews of non-randomized studies?

Background There is a lack of an instrument to evaluate systematic reviews of non-randomized studies in epidemiological research. The Assessment of Multiple Systematic Reviews (AMSTAR) is widely used to evaluate the scientific quality of systematic reviews, but it has not been validated for SRs of non-randomized studies. The objective of this paper is to report our experience in ...

A systematic review of the impact of volume of surgery and specialization in Norwood procedure

Background The volume-outcome relationship is supposed to be stronger in high risk, low volume procedures. The aim of this systematic review is to examine the available literature on the effects of hospital and surgeon volume, specialization and regionalization on the outcomes of the Norwood procedure. Methods A systematic literature search was performed in Medline, Embase, and the ...

Factors influencing adherence in Hepatitis-C infected patients: a systematic review

Background Adherence is a crucial point for the successful treatment of a hepatitis-C virus infection. Studies have shown that especially adherence to ribavirin is important.The objective of this systematic review was to identify factors that influence adherence in hepatitis-C infected patients taking regimes that containing ribavirin. Methods A systematic literature search was ...

Methods of international health technology assessment agencies for economic evaluations- a comparative analysis

Background The number of Health Technology Assessment (HTA) agencies increases. One component of HTAs are economic aspects. To incorporate economic aspects commonly economic evaluations are performed. A convergence of recommendations for methods of health economic evaluations between international HTA agencies would facilitate the adaption of results to different settings and avoid ...

Negative pressure wound therapy versus standard wound care in chronic diabetic foot wounds: study protocol for a randomized controlled trial

: Zentrum fr Klinische Studien und Innovation (ZKSI)) (Department for Clinical Research) she is responsible for the medical and scientific issues. Tim Mathes is a Dipl. health economist with a study focus on