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The combination of cardiorespiratory fitness and muscle strength, and mortality risk

Little is known about the combined associations of cardiorespiratory fitness (CRF) and hand grip strength (GS) with mortality in general adult populations. The purpose of this study was to compare the relative risk of mortality for CRF, GS, and their combination. In UK Biobank, a prospective cohort of > 0.5 million adults aged 40–69 years, CRF was measured through submaximal bike...

The Influence of Objectively Measured Physical Activity During Pregnancy on Maternal and Birth Outcomes in Urban Black South African Women

Objectives Research indicates the beneficial effects of physical activity during pregnancy on maternal health, although controversy still exists regarding its influence on birth outcomes. Little research has been done to objectively measure physical activity during pregnancy in black African women from low-to-middle income countries. The purpose of this study was to examine the...

Estimation of Physical Activity Energy Expenditure during Free-Living from Wrist Accelerometry in UK Adults

). - Funding: This work was funded by the Medical Research Council (MC_UU_12015/3), and Tom White is the recipient of a studentship from MedImmune. The funders had no role in the Background Methods Results ... thanks to Stefanie Hollidge and Lewis Griffiths for their assistance in processing the physical activity data. This work was funded by the Medical Research Council (MC_UU_12015/3) and Tom White is the

Large Scale Population Assessment of Physical Activity Using Wrist Worn Accelerometers: The UK Biobank Study

Background Physical activity has not been objectively measured in prospective cohorts with sufficiently large numbers to reliably detect associations with multiple health outcomes. Technological advances now make this possible. We describe the methods used to collect and analyse accelerometer measured physical activity in over 100,000 participants of the UK Biobank study, and...

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

, UKSara M. Willems, Daniel J. Wright, Felix R. Day, Luca A. Lotta, Tom White, Søren Brage, Jing Hua Zhao, Claudia Langenberg, John R. B. Perry, Nick J. Wareham & Robert A. ScottDepartment of Internal ... for Tom White in:Nature Research journals • PubMed • Google ScholarSearch for Po-Ru Loh in:Nature Research journals • PubMed • Google ScholarSearch for Mette Aadahl in:Nature Research journals • PubMed