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Time course of immature platelet count and its relation to thrombocytopenia and mortality in patients with sepsis

Medical University Hospital, Tochigi, Japan. Author Contributions Conceptualization: Kansuke Koyama. Data curation: Kansuke Koyama, Shinshu Katayama, Tomohiro Muronoi, Ken Tonai, Yuya Goto. Formal ... analysis: Kansuke Koyama, Tomohiro Muronoi. Investigation: Toshitaka Koinuma, Jun Shima. Methodology: Kansuke Koyama. Supervision: Shin Nunomiya. Writing ± original draft: Kansuke Koyama. Writing

Ex-vivo and live animal models are equally effective training for the management of a penetrating cardiac injury

Background Live tissue models are considered the most useful simulation for training in the management for hemostasis of penetrating injuries. However, these models are expensive, with limited opportunities for repetitive training. Ex-vivo models using tissue and a fluid pump are less expensive, allow repetitive training and respect ethical principles in animal research. The...

Ex-vivo porcine organs with a circulation pump are effective for teaching hemostatic skills

Surgical residents have insufficient opportunites to learn basic hemostatic skills from clinical experience alone. We designed an ex-vivo training system using porcine organs and a circulation pump to teach hemostatic skills. Residents were surveyed before and after the training and showed significant improvement in their self-confidence (1.83 ± 1.05 vs 3.33 ± 0.87, P < 0.01) on...