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Factors Associated with Maternal Serum Levels of Perfluoroalkyl Substances and Organochlorines: A Descriptive Study of Parous Women in Norway and Sweden

Introduction Perfluoroalkyl substances (PFASs) and organochlorines (OCs) are ubiquitous and persistent in the environment and proposed endocrine disrupting chemicals (EDCs). They can be transferred across the placenta during pregnancy, and studies suggest that the prenatal period may be particularly sensitive for influences on fetal growth and development. Several studies have...

Consumption of Lean Fish Reduces the Risk of Type 2 Diabetes Mellitus: A Prospective Population Based Cohort Study of Norwegian Women

Background The effects of fish consumption and n-3 fatty acids on type 2 diabetes mellitus (T2DM) have recently been debated. Objective We explored the risk of T2DM in relation to consumption of lean fish, fatty fish, fish products and total fish as well as cod liver oil supplements in a representative sample of Norwegian women. Design This was a prospective population based...

Persistent organic pollutants in meat, liver, tallow and bone marrow from semi-domesticated reindeer (Rangifer tarandus tarandus L.) in Northern Norway

Background The aim of this project was to study 14 polychlorinated biphenyls (PCBs), 5 dichlorodiphenyl trichloroethans (DDTs), 12 organochlorine pesticides (OCPs) and 6 polybrominated diphenylethers (PBDEs) in meat, liver, tallow and bone marrow from semi-domesticated reindeer. Methods Meat, liver, tallow, and bone marrow samples (n= 30) were collected from semi-domesticated...

Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation

Several studies have recently identified strong epigenetic signals related to tobacco smoking. However, an aspect that did not receive much attention is the evolution of epigenetic changes with time since smoking cessation. We conducted a series of epigenome-wide association studies to capture the dynamics of smoking-induced epigenetic changes after smoking cessation, using...

Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

Flower 1 Ed Curry 1 Nicholas Orr Katarzyna Tomczyk Michael E. Jones Alan Ashworth Anthony Swerdlow Marc Chadeau-Hyam 4 Eiliv Lund Montserrat Garcia-Closas Torkjel M. Sandanger James M. Flanagan 0 1 Paolo