The aim of this study was to evaluate the efficacy and safety of first-line chemotherapy with re-introduction of oxaliplatin (OX) more than 6 months after adjuvant chemotherapy including OX. Stage II/III colon cancer patients with neuropathies of grade ≤ 1 who relapsed more than 6 months after adjuvant chemotherapy including OX were considered eligible. Eligible patients were...
). Author information Affiliations Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan Keisuke Kazama, Masakatsu Numata, Toru Aoyama, Yosuke Atsumi, Hiroshi ... PubMed Google Scholar Toru Aoyama View author publications You can also search for this author in PubMed Google Scholar Yosuke Atsumi View author publications You can also search for this author
, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan Masakatsu Numata, Hiroshi Tamagawa, Keisuke Kazama, Shinnosuke Kawahara, Toru Aoyama, Yukio Maezawa, Kazuki Kano, Norio Yukawa & Yasushi ... can also search for this author in PubMed Google Scholar Sho Sawazaki View author publications You can also search for this author in PubMed Google Scholar Toru Aoyama View author publications
PurposeThis study investigated the efficacy and safety of cetuximab-based treatment in patients with chemotherapy-resistant refractory mCRC with KRAS G13D mutation.Patients and methodsAn assessment of the efficacy and safety of cetuximab-based treatment was performed in an observation-enriched randomized controlled study comparing the cetuximab alone group (Cet group) and the...
Yasuhiko Ito Toru Aoyama Daisuke Kamoi Takashi Sakakibara Norio Umemoto Yoshitaka Kumada Susumu Suzuki Toyoaki Murohara Protein-energy wasting (PEW) is highly prevalent in hemodialysis (HD) patients ... . Author Contributions: Conception and design: Hideki Ishii, Hiroshi Takahashi, and Yasuhiko Ito; Analysis and interpretation: Hideki Ishii, Yasuhiko Ito, Toru Aoyama, Takashi Sakakibara, Norio Umemoto
, Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, JapanToru Aoyama, Tsutomu Sato, Takashi Oshima, Yasushi Rino & Munetaka Masuda AuthorsSearch for Kazuki Kano in:PubMed • Google Scholar Search for Toru ... Aoyama in:PubMed • Google Scholar Search for Tetsushi Nakajima in:PubMed • Google Scholar Search for Yukio Maezawa in:PubMed • Google Scholar Search for Tsutomu Hayashi in:PubMed • Google Scholar
because the DFS was slightly worse in the UFT and PSK arm than in the surgery-alone arm. - Toru Aoyama contributed equally to the Kiyotaka Okuno. Department of Surgery, Kindai University Faculty of
-institutional study (YSURG1401) Keisuke Kazama†1, Toru Aoyama†1Email author, Tsutomu Hayashi1, Takanobu Yamada1, Masakatsu Numata1, Shinya Amano1, Mariko Kamiya1, Tsutomu Sato1, Takaki Yoshikawa2, Manabu
Purpose Hangeshashinto (TJ-14, a Kampo medicine), which reduces the level of prostaglandin E2 and affects the cyclooxygenase activity, alleviates chemotherapy-induced oral mucositis (COM). We conducted a double-blind, placebo-controlled, randomized comparative trial to investigate whether TJ-14 prevents and controls COM in patients with colorectal cancer. Methods Ninety-three...
Background The safety and feasibility of administering S-1 adjuvant chemotherapy for gastric cancer has not been fully evaluated in elderly patients. Methods This retrospective study selected patients who underwent curative D2 surgery for gastric cancer, were diagnosed with stage II or III disease, and received adjuvant S-1 at our institution. Patients were categorized into two...
Background In patients with stage II/III gastric cancer, tumors often recur even after curative D2 gastrectomy followed by adjuvant S-1 chemotherapy. The objective of this retrospective study was to clarify the prognostic factors in these patients that might be useful for future patients. Methods Overall survival (OS) was examined in 82 gastric cancer patients who underwent...
BackgroundThe factors that affect the 6-month continuation of adjuvant chemotherapy with S-1 have not been fully evaluated. The objective of this retrospective study was to clarify the risk factors for 6-month continuation of S-1 adjuvant chemotherapy.MethodsThe study selected patients who underwent curative D2 surgery for gastric cancer, were diagnosed with stage 2 or 3 disease...
Background Some patients experience a recurrence of cancer even after curative D2 gastrectomy followed by adjuvant S-1 chemotherapy. The objective of this retrospective study was to clarify the survival and prognosticators in these patients. Methods The study selected patients who underwent curative D2 surgery, were diagnosed with stage II, IIIA, or IIIB cancer, received adjuvant...
BackgroundA significant body weight loss (BWL) is observed during 1 month after gastrectomy for gastric cancer. However, it remains unclear which body component mainly accounts for the weight loss.MethodsTwo-hundred forty-four patients who underwent gastrectomy for gastric cancer between May 2010 and October 2013 were examined. Body weight and composition were evaluated by a...
Background Hangeshashinto (TJ-14, a Kampo medicine), which reduces the level of prostaglandin E2 and affects the cyclooxygenase activity, alleviates chemotherapy-induced oral mucositis (COM). We conducted a randomized comparative trial to investigate whether TJ-14 prevents and controls COM in patients with gastric cancer. Methods We randomly assigned patients with gastric cancer...
Background. Chronic haemodialysis patients are at an increased risk of peripheral artery disease (PAD). Although percutaneous transluminal angioplasty (PTA) has become a widely used therapeutic intervention for PAD, its outcome in haemodialysis patients remains poorly understood. The aim of this study was to clarify the long-term outcome of PTA as a primary treatment for PAD in...
Background Enhanced recovery after surgery (ERAS) programs have been reported to be feasible and useful for maintaining physiological function and facilitating recovery after colorectal surgery. The feasibility of such programs in gastric surgery remains unclear. This study assessed whether an ERAS program is feasible in patients who undergo gastric surgery. Methods The subjects...
, JapanTakanobu Yamada, Tsutomu Hayashi, Toru Aoyama, Junya Shirai, Hirohito Fujikawa, Haruhiko Cho, Takaki Yoshikawa & Akira TsuburayaDepartment of Surgery, Yokohama City University, Yokohama, JapanTakanobu Yamada ... , Tsutomu Hayashi, Toru Aoyama, Junya Shirai, Hirohito Fujikawa, Yasushi Rino & Munetaka MasudaDepartment of Anesthesiology, Kanagawa Cancer Center, 1-1-2 Nakao, Asahi, 241-0815, Yokohama, Kanagawa
Background The aim of this prospective study was to evaluate the feasibility and safety of laparoscopy-assisted distal gastrectomy (LADG) initiated by surgeons with much experience of open gastrectomy and laparoscopic surgery. Methods Three surgeons who each had experience with more than 300 cases of open gastrectomy, more than 100 cases of laparoscopic cholecystectomy, more than...
Background Radical antegrade modular pancreatosplenectomy (RAMPS) is a relatively new modification of the standard distal pancreatosplenectomy. In this method, dissection proceeds from right-to-left to achieve negative posterior resection margins. However, short-term and long-term outcomes of RAMPS for pancreatic cancer have not yet been clarified. The aim of this study is to...
