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Search: authors:"Troester, Melissa A."

7 papers found.
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Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study

African American breast cancer patients have lower frequency of hormone receptor–positive (HR+)/human epidermal growth factor receptor 2 (HER2)–negative disease and higher subtype-specific mortality. Racial differences in molecular subtype within clinically defined subgroups are not well understood.

Demographic, lifestyle, and genetic determinants of circulating concentrations of 25-hydroxyvitamin D and vitamin D–binding protein in African American and European American women

Background: Vitamin D may have anticancer activities. The high prevalence of vitamin D deficiency in African Americans (AAs) may be a contributing factor to the cancer health disparities between AAs and European Americans (EAs).

A case–control analysis of smoking and breast cancer in African American women: findings from the AMBER Consortium

Recent population studies suggest a role of smoking in the etiology of breast cancer, but few have been conducted among African American women. In a collaborative project of four large studies, we examined associations between smoking measures and breast cancer risk by menopause and hormone receptor status [estrogen receptor-positive (ER+), ER-negative (ER−) and triple-negative...

Postmenopausal Female Hormone Use and Estrogen Receptor–Positive and –Negative Breast Cancer in African American Women

Use of estrogen with progestin (combination therapy) is associated with increased incidence of estrogen receptor–positive (ER+) breast cancer in observational studies and randomized trials among postmenopausal white women. Whether this is also the case among African American women is not established.

Formation and Removal of Pentachlorophenol-Derived Protein Adducts in Rodent Liver under Acute, Multiple, and Chronic Dosing Regimens

We investigated the kinetics of production and elimination of chlorinated quinone adducts of liver cytosolic proteins derived from pentachlorophenol (PCP), following oral administration under acute dosing (0–40 mg/kg body weight [bw] in Sprague-Dawley rats, 0–120 mg/kg bw in F344 rats, and 0–60 mg/kg bw in B6C3F1 mice), multiple dosing (0–60 mg/kg bw/day for 5 days in F344 rats...

Stability of Hemoglobin and Albumin Adducts of Benzene Oxide and 1,4-Benzoquinone after Administration of Benzene to F344 Rats

The stability of cysteinyl adducts of benzene oxide (BO) and mono-S-substituted cysteinyl adducts of 1,4-benzoquinone (1,4-BQ) was investigated in both hemoglobin (Hb) and albumin (Alb) following administration of a single oral dose of 400 mg [U-14C/13C6]benzene/kg body weight to F344 rats. Total radiobound adducts to Hb were stable, as were adducts formed by the reaction of...