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Performance of Multimodel Schemes for Seasonal Precipitation over Indian Region

Christi, TX 78412, USA 2Department of Statistics, Visva Bharati University, Bolpur Santiniketan, West Bengal 731235, India Correspondence should be addressed to Vinay Kumar; ude.ccumat@ramuk.yaniv ... Received 5 July 2017; Revised 15 October 2017; Accepted 8 November 2017; Published 3 January 2018 Academic Editor: Takashi Mochizuki Copyright © 2018 Vinay Kumar and Tirthankar Ghosh. This is an open

In vitro and in vivo toxicity assessment of nanoparticles

Nanotechnology has revolutionized gene therapy, diagnostics and environmental remediation. Their bulk production, uses and disposal have posed threat to the environment. With the appearance of these nanoparticles in the environment, their toxicity assessment is an immediate concern. This review is an attempt to summarize the major techniques used in cytotoxity determination. The...

A prospective analysis of risk factors for pediatric burn mortality at a tertiary burn center in North India

Background None of the available mortality predicting models in pediatric burns precisely predicts outcomes in every population. Mortality rates as well as their risk factors vary with regions and among different centers within the regions. The aim of this study was to identify socio-demographic and clinical risk factors for mortality in pediatric burns in an effort to decrease...

Antiproliferative and apoptotic effects of black turtle bean extracts on human breast cancer cell line through extrinsic and intrinsic pathway

Vinay Kumar Sharma 0 Savita Yadav 0 Sharmistha Dey 0 0 Department of Biophysics, All India Institute of Medical Sciences , Ansari Nagar, New Delhi 110 029 , India The black turtle bean (BTB) is most

Biodegradation of endocrine disruptor dibutyl phthalate (DBP) by a newly isolated Methylobacillus sp. V29b and the DBP degradation pathway

Bacteria of the genus Methylobacillus are methanotrophs, a metabolic feature that is widespread in the phylum Proteobacteria. The study demonstrates the isolation and characterization of a newly isolated Methylobacillus sp. V29b. which grows on methanol, protocatechuate, monobutyl phthalate, dibutyl phthalate, diethyl phthalate, benzyl butyl phthalate, dioctyl phthalate and...

Leaky Integrate and Fire Neuron by Charge-Discharge Dynamics in Floating-Body MOSFET

, Government of India for partially funding this work. Vinay Kumar is supported by Intel India Ph.D. Fellowship. The authors would like to acknowledge technical discussions with Narayan Srinivasa, Srinivas ... Subramoney and their team at Intel. Author information AffiliationsDepartment of Electrical Engineering, IIT Bombay, Mumbai, 400076, IndiaSangya Dutta, Vinay Kumar, Aditya Shukla & Udayan GangulyDepartment

Genome-wide Identification and Structural, Functional and Evolutionary Analysis of WRKY Components of Mulberry

 & Paramjit Khurana AuthorsSearch for Vinay Kumar Baranwal in:Nature Research journals • PubMed • Google ScholarSearch for Nisha Negi in:Nature Research journals • PubMed • Google ScholarSearch for Paramjit

Photomediated Larvicidal Activity of Pheophorbide a against Cercaria Larvae of Fasciola gigantica

Fasciolosis is a parasitic disease caused by Fasciola gigantica. The freshwater snail Lymnaea acuminata is the intermediate host of F. gigantica which cause endemic fasciolosis in the northern part of India. To investigate larvicidal activity of pure and laboratory extracted pheophorbide a (Pa) against cercaria larvae of F. gigantica, data were analyzed in different spectra of...

Effects of histatin-1 peptide on human corneal epithelial cells

Purpose Ocular surface and corneal epithelial wounds are common and potentially debilitating problems. Ideal treatments for these injuries would promote epithelial healing without inflammation, infection and scarring. In addition the best treatments would be cost-efficient, effective, non-toxic and easily applied. Histatin-1 peptides have been shown to be safe and effective...

Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies

Altered metabolism is an emerging hallmark of cancer, as malignant cells display a mammoth up-regulation of enzymes responsible for steering their bioenergetic and biosynthetic machinery. Thus, the recent anticancer therapeutic strategies focus on the targeting of metabolic enzymes, which has led to the identification of specific metabolic inhibitors. One of such inhibitors is 3...

Magnetohydrodynamics flow of a nanofluid driven by a stretching/shrinking sheet with suction

The present paper investigates the effect of a mathematical model describing the aforementioned process in which the ambient nanofluid in the presence of suction/injection and magnetic field are taken into consideration. The flow is induced by an infinite elastic sheet which is stretched along its own plane. The stretching/shrinking of the sheet is assumed to be proportional to...

The CRISPR–Cas system for plant genome editing: advances and opportunities

Genome editing is an approach in which a specific target DNA sequence of the genome is altered by adding, removing, or replacing DNA bases. Artificially engineered hybrid enzymes, zinc-finger nucleases (ZFNs), and transcription activator-like effector nucleases (TALENs), and the CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated protein...

Human Lacrimal Gland Gene Expression

Background The study of human lacrimal gland biology and development is limited. Lacrimal gland tissue is damaged or poorly functional in a number of disease states including dry eye disease. Development of cell based therapies for lacrimal gland diseases requires a better understanding of the gene expression and signaling pathways in lacrimal gland. Differential gene expression...

G9a inhibits MEF2C activity to control sarcomere assembly

Palanichamy Kala, Vinay Kumar Rao, Min Hee Choi, Narendra Bharathy & Reshma TanejaNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, 117456, SingaporeJin Rong Ow ... ScholarSearch for Vinay Kumar Rao in:Nature Research journals • PubMed • Google ScholarSearch for Min Hee Choi in:Nature Research journals • PubMed • Google ScholarSearch for Narendra Bharathy in:Nature Research

Chlorophyllin Bait Formulation and Exposure to Different Spectrum of Visible Light on the Reproduction of Infected/Uninfected Snail Lymnaea acuminata

Fasciolosis is a waterborne disease, caused by Fasciola species. Snail Lymnaea acuminata is an intermediate host of these flukes. Control of snail population is major tool in reducing the incidences. Variation in light intensity and wavelength caused significant changes in reproduction pattern of snails. Maximum fecundity was noted with bait containing carbohydrate (starch, 468...

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

Lysine methylation is abundant on histone proteins, representing a dynamic regulator of chromatin state and gene activity, but is also frequent on many non-histone proteins, including eukaryotic elongation factor 1 alpha (eEF1A). However, the functional significance of eEF1A methylation remains obscure and it has remained unclear whether eEF1A methylation is dynamic and subject...

Deciphering Transcriptional Programming during Pod and Seed Development Using RNA-Seq in Pigeonpea (Cajanus cajan)

Seed development is an important event in plant life cycle that has interested humankind since ages, especially in crops of economic importance. Pigeonpea is an important grain legume of the semi-arid tropics, used mainly for its protein rich seeds. In order to understand the transcriptional programming during the pod and seed development, RNA-seq data was generated from embryo...

G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation

Differentiation of skeletal muscle cells, like most other cell types, requires a permanent exit from the cell cycle. The epigenetic programming underlying these distinct cellular states is not fully understood. In this study, we provide evidence that the lysine methyltransferase G9a functions as a central axis to regulate proliferation and differentiation of skeletal muscle cells...