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38 papers found.
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Estimating the Number of Measles-Susceptible Children and Adolescents in the United States Using Data From the National Immunization Survey–Teen (NIS-Teen)

(Robert A. Bednarczyk , Saad B. Omer); Emory Vaccine Center, Emory University , Atlanta, Georgia (Robert A. Bednarczyk , Walter A. Orenstein, Saad B. Omer); Division of Infectious Diseases, Department of ... Medicine, School of Medicine, Emory University , Atlanta , Georgia ( Walter A. Orenstein); and Department of Pediatrics, School of Medicine, Emory University , Atlanta , Georgia ( Saad B. Omer). This project

The role of supplementary environmental surveillance to complement acute flaccid paralysis surveillance for wild poliovirus in Pakistan – 2011–2013

. Pallansch, Walter A. Orenstein. Formal analysis: Tori L. Cowger, Howard E. Gary, Jr., Jane Iber, Elizabeth Henderson. Investigation: Cara C. Burns, Salmaan Sharif, Jane Iber, Elizabeth Henderson, Farzana ... Malik, Syed Sohail Zahoor Zaidi, Shahzad Shaukat. 13 / 16 Methodology: Tori L. Cowger, Cara C. Burns, Howard E. Gary, Jr., Mark A. Pallansch, Walter A. Orenstein. Writing ± original draft: Tori L

Protective Effect of Contemporary Pertussis Vaccines: A Systematic Review and Meta-analysis

Background. Acellular pertussis (aP) and whole-cell (wP) pertussis vaccines are presumed to have similar short-term (<3 years after completion of the primary series) efficacy. However, vaccine effect varies between individual pertussis vaccine formulations, and many originally studied formulations are now unavailable. An updated analysis of the short-term protective effect of...

Impact of Statins on Influenza Vaccine Effectiveness Against Medically Attended Acute Respiratory Illness

Background. Statins have antiinflammatory effects that may impact vaccine-induced immune responses. We investigated the impact of statin therapy on influenza vaccine effectiveness (VE) against medically attended acute respiratory illness (MAARI). Methods. We conducted a retrospective cohort study over nine influenza seasons using research databases of a large managed care...

Editorial Commentary: Intussusception and Rotavirus Vaccination—Balancing Risk Against Benefit

Umesh D. Parashar 1 Walter A. Orenstein 0 0 Emory University School of Medicine , Atlanta , Georgia 1 National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and

Epidemiology of Pertussis Among Young Pakistani Infants: A Community-Based Prospective Surveillance Study

Background. Pertussis remains a cause of morbidity and mortality among young infants. There are limited data on the pertussis disease burden in this age group from low- and lower-middle-income countries, including in South Asia. Methods. We conducted an active community-based surveillance study from February 2015 to April 2016 among 2 cohorts of young infants in 4 low-income...

Maternal Influenza Immunization and Birth Outcomes of Stillbirth and Spontaneous Abortion: A Systematic Review and Meta-analysis

Despite strong evidence that maternal influenza vaccination during pregnancy is safe, uptake of influenza vaccination during pregnancy remains low. We identified studies that assessed outcomes of stillbirth or spontaneous abortion after administration of influenza vaccine during pregnancy. We conducted a literature search in November 2013 that yielded 447 total citations. After...

Editorial Commentary: A Rare Event: A Measles Outbreak in a Population With High 2-Dose Measles Vaccine Coverage

Jane F. Seward () 1 Walter A. Orenstein 0 0 Emory University School of Medicine , Atlanta, Georgia 1 Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for

Health Disparities in Human Papillomavirus Vaccine Coverage: Trends Analysis From the National Immunization Survey–Teen, 2008–2011

Adolescent uptake of human papillomavirus (HPV) vaccine remains low. We evaluated HPV vaccine uptake patterns over 2008–2011 by race/ethnicity, poverty status, and the combination of race/ethnicity and poverty status, utilizing National Immunization Survey–Teen data. Minority and below-poverty adolescents consistently had higher series initiation than white and above-poverty...

Vaccine-preventable Diseases, Immunizations, and the Epidemic Intelligence Service

, Decatur, Georgia (Alan R. Hinman); Bill and Melinda Gates Foundation, Seattle, Washington (Walter A. Orenstein); and National Center for Immunization and Respiratory Diseases, Atlanta, Georgia (Anne

Factors Associated with Intention to Receive Influenza and Tetanus, Diphtheria, and Acellular Pertussis (Tdap) Vaccines during Pregnancy: A Focus on Vaccine Hesitancy and Perceptions of Disease Severity and Vaccine Safety

BACKGROUND: Improving influenza and tetanus, diphtheria and acellular pertussis (Tdap) vaccine coverage among pregnant women is needed. PURPOSE: To assess factors associated with intention to receive influenza and/or Tdap vaccinations during pregnancy with a focus on perceptions of influenza and pertussis disease severity and influenza vaccine safety. METHODS: Participants were...

Completeness of Measles Case Reporting: Review of Estimates for the United States

Measles surveillance is complex: the patient must seek health care, the diagnosis must be recognized by the physician, and the case must be reported to health departments. The portion of total (incident) measles cases⩾ that is reported to health departments is termed “completeness of reporting.” Few studies describe this measure of the quality of surveillance in the United States...

Pertussis in Adults: Epidemiology, Signs, Symptoms, and Implications for Vaccination

Transmission of pertussis among adults is being increasingly recognized. About 1 or 2 in 1,000 adolescents and adults develop pertussis each year, ⩾12% of persons with acute cough illnesses of at least 1–2 weeks' duration have evidence of pertussis infection, and adults have been the source of pertussis for younger children. The advent of acellular pertussis vaccines, if safe and...

Defining and Assessing Measles Elimination Goals

Although 3 of 6 World Health Organization regions have established measles elimination targets, measles elimination goals are not well defined. In general, disease elimination has been defined as the reduction of incidence in a population to zero. However, measles is so contagious that zero incidence is difficult to achieve and sustain because the risk of imported measles remains...

The Theory of Measles Elimination: Implications for the Design of Elimination Strategies

The theory of disease transmission provides a consistent framework within which to design, evaluate, and monitor measles elimination programs. Elimination of measles requires maintaining the effective reproduction number R at <1, by achieving and maintaining low levels of susceptibility. The essential features of different vaccination strategies (e.g., routine versus campaigns...

A Retrospective Evaluation of Hospitalizations for Acute Gastroenteritis at 2 Sentinel Hospitals in Central Japan to Estimate the Health Burden of Rotavirus

BackgroundTwo rotavirus vaccines have recently been licensed for use in >80 countries worldwide but not in Japan. To assess the value of introducing rotavirus vaccination in Japan, data on the burden of rotavirus disease are needed MethodsTo describe the epidemiology of severe rotavirus disease among Japanese children aged <5 years, we examined retrospective demographic, clinical...

Financing Immunizations in the United States

Children in the United States receive immunizations through both private and public sectors. The federal government has supported childhood immunization since 1963 through the Vaccination Assistance Act (Section 317 of the Public Health Service Act). Since 1994, the Vaccines for Children (VFC) program has provided additional support for childhood vaccines. In 2002, 41% of...