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12 papers found.
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Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations

Health care-associated infections (HAI) are a major public health problem with a significant impact on morbidity, mortality and quality of life. They represent also an important economic burden to health systems worldwide. However, a large proportion of HAI are preventable through effective infection prevention and control (IPC) measures. Improvements in IPC at the national and ...

Ventilator-associated pneumonia in neonates, infants and children

Ventilator-associated pneumonia (VAP) is relatively common in mechanically-ventilated children, but there is a wide variation in reported VAP rates, depending on settings and geographical regions. Surveillance definitions in children are challenging. Although these are provided by the German nosocomial infection surveillance system and an independent Dutch group, the combination of ...

Healthcare-Associated Infections Are Associated with Insufficient Dietary Intake: An Observational Cross-Sectional Study

Background Indicators to predict healthcare-associated infections (HCAI) are scarce. Malnutrition is known to be associated with adverse outcomes in healthcare but its identification is time-consuming and rarely done in daily practice. This cross-sectional study assessed the association between dietary intake, nutritional risk, and the prevalence of HCAI, in a general hospital ...

Bench-to-bedside review: Challenges of diagnosis, care and prevention of central catheter-related bloodstream infections in children

Central venous catheters (CVCs) are indispensable in modern pediatric medicine. CVCs provide secure vascular access, but are associated with a risk of severe complications, in particular bloodstream infection. We provide a review of the recent literature about the diagnostic and therapeutic challenges of catheter-related bloodstream infection (CRBSI) in children and its prevention. ...

Hospital-Wide Multidisciplinary, Multimodal Intervention Programme to Reduce Central Venous Catheter-Associated Bloodstream Infection

Central line-associated bloodstream infection (CLABSI) is the major complication of central venous catheters (CVC). The aim of the study was to test the effectiveness of a hospital-wide strategy on CLABSI reduction. Between 2008 and 2011, all CVCs were observed individually and hospital-wide at a large university-affiliated, tertiary care hospital. CVC insertion training started ...

Implementation of infection control best practice in intensive care units throughout Europe: a mixed-method evaluation study

Background The implementation of evidence-based infection control practices is essential, yet challenging for healthcare institutions worldwide. Although acknowledged that implementation success varies with contextual factors, little is known regarding the most critical specific conditions within the complex cultural milieu of varying economic, political, and healthcare systems. ...

Determinants of body weight gain and association with neurodevelopmental outcome in infants operated for congenital heart disease☆

The aim of this prospective study was to examine the determinants of growth failure and the association with neurodevelopmental outcome in infants undergoing open-heart surgery. In 107 infants undergoing open-heart surgery for congenital heart disease (CHD), we evaluated weight at birth, at surgery, and at one year of age (expressed as z-scores). Neurodevelopmental status was ...

The control of the acid-base balance during open-heart surgery

Many aspects of the acid-base balance during extracorporeal circulation and during hypothermia are still problematic. In this paper the theoretical background is reviewed which led to the adoption of the following working hypothesis. The acid-base balance has a direct influence on two important aspects of cardiopulmonary bypass During bypass a high carbon dioxide tension will ...

The prevention of shock following extracorporeal circulation and hypothermia

Nous avons passé en revue les opinions courantes sur les traitements des malades sous les machines cceur-poumon, avec ou sans hypothermie. Si l’on désire des suites opératoires sans incident et prevenir le choc, il faut surveiller les points suivants: un debit suffisant; une hypervolemie legere, pendant et aprés la dérivation et l’iypothermie; un emploi minimum QU systeme de ...