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Long-term variation of satellite-based PM2.5 and influence factors over East China

in:Nature Research journals • PubMed • Google Scholar Search for Wei Gao in:Nature Research journals • PubMed • Google Scholar Search for Yanyu Wang in:Nature Research journals • PubMed • Google Scholar ... Search for Tiantao Cheng in:Nature Research journals • PubMed • Google Scholar Contributions Qianshan He, Fuhai Gen and Chengcai Li designed the study. Haizhen Mu, Guangqiang Zhou, Xiaobo Liu, Wei Gao

Overexpression of PEAK1 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling

Pseudopodium-enriched atypical kinase 1 (PEAK1), a novel non-receptor tyrosine kinase, has been demonstrated to act as an oncogenic regulator in breast and pancreatic cancers. However, the role of PEAK1 in the progression and metastasis of lung cancer is still unknown. Here, we observed that ectopic PEAK1 expression promoted lung cancer cell migration and invasion, while PEAK1...

Fabrication of a Porous Metal-Organic Framework with Polar Channels for 5-Fu Delivery and Inhibiting Human Osteosarcoma Cells

As an emerging kind of crystalline material, the metal-organic framework (MOF) has shown great promise in the biomedical domains such as drug storage and delivery. In this study, a new porous MOF, [[Dy2(H2O)3(SDBA)3](DMA)6] (1, H2SDBA = 4,4′-sulfonyldibenzoic acid, DMA = N,N-dimethylacetamide (C4H9NO)), with uncoordinated O donor sites has been fabricated using a bent...

Fabrication of a Porous Metal-Organic Framework with Polar Channels for 5-Fu Delivery and Inhibiting Human Osteosarcoma Cells

As an emerging kind of crystalline material, the metal-organic framework (MOF) has shown great promise in the biomedical domains such as drug storage and delivery. In this study, a new porous MOF, [[Dy2(H2O)3(SDBA)3](DMA)6] (1, H2SDBA = 4,4′-sulfonyldibenzoic acid, DMA = N,N-dimethylacetamide (C4H9NO)), with uncoordinated O donor sites has been fabricated using a bent...

Microbial diversity and ecotoxicity of sediments 3 years after the Jiaozhou Bay oil spill

In 2013, the “Qingdao oil pipeline explosion” released an estimated 2000 tons of oil into the environment. Sediment samples were collected from ten sites in Jiaozhou Bay and Shilaoren Beach to evaluate the influence of the spilled oil on the benthic environment 3 years after the oil spill accident. The compositions of oil, bacterial diversity and biotoxicity were examined in this...

Hazardous Gas Emission Monitoring Based on High-Resolution Images

Air pollution presents unprecedentedly severe challenges to humans today. Various measures have been taken to monitor pollution from gas emissions and the changing atmosphere, of which imaging is of crucial importance. By images of target scenes, intuitional judgments and in-depth data are achievable. However, due to the limitations of imaging devices, effective and efficient...

Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells

Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells Jin-xiao Liang,1 Wei Gao,2 Lei Cai1 1Department of Thoracic Surgery, Zhejiang Cancer Hospital, 2School of ... OncoTargets and Therapy Fucosyltransferase Vii promotes proliferation via the egFr/aKT/mTOr pathway in a549 cells Jin-xiao liang 1 Wei gao 0 lei cai 1 0 s chool of Medicine, Zhejiang University c

Active Surface Compensation for Large Radio Telescope Antennas

With the development of radio telescope antennas with large apertures, high gain, and wide frequency bands, compensation methods, such as mechanical or electronic compensation, are obviously essential to ensure the electrical performance of antennas that work in complex environments. Since traditional compensation methods can only adjust antenna pointing but not the surface...

Novel Biocompatible Au Nanostars@PEG Nanoparticles for In Vivo CT Imaging and Renal Clearance Properties

Nanoprobes are rapidly becoming potentially transformative tools on disease diagnostics for a wide range of in vivo computed tomography (CT) imaging. Compared with conventional molecular-scale contrast agents, nanoparticles (NPs) promise improved abilities for in vivo detection. In this study, novel polyethylene glycol (PEG)-functionalized Au nanoparticles with star shape (AuNS...

Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease

of Health (P30DK081943 and K08HL130944). Author Contributions Conceptualization: Guisong Wang, Wei Gao, Jifeng Zhang, Y. Eugene Chen, Subramaniam Pennathur. Data curation: Guisong Wang, Anna ... Vachaparampil Mathew, Haiyi Yu, Lei Li, Liyun He, Wei Gao, Xiaodan Liu, Yanhong Guo, Jaeman Byun, Jifeng Zhang, Y. Eugene Chen. Formal analysis: Guisong Wang, Anna Vachaparampil Mathew, Haiyi Yu, Lei Li, Liyun

Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil

Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil Sheng Zhu, Yu-Hui Yang, Rong-Wei Gao, Ran Li, Yu-Zhen Zou, Lei Feng, Bo Zhang Department of

Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

Wang,2 Penghui Wang,2 Wei Gao,1 Fenge Li,3 Xueling Yang,1 Hongyan Ni,2 Wen Shen,2 Zhi Guo1 1Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National

Higher yields of hybrid rice do not depend on nitrogen fertilization under moderate to high soil fertility conditions

Background Increasing rice yield with fewer external inputs is critical to ensuring food security, reducing environmental costs, and improving returns. Use of hybrid rice has expanded greatly in China due to its higher yield potential. Meanwhile, large and increasing amounts of nitrogen (N) fertilizers have been used for expanding rice production in China. It is not clear to what...

Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer

Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer Fei Yang,1,* Jun-Yi Gao,2,* Hua Chen,1 Zhen-Hua Du,1 Xue-Qun Zhang,3 Wei Gao4 1Department of Pathology, Jinan Central Hospital Affiliated to Shandong University, Jinan, 2Department of Clinical Medicine, Weifang Medical College, Weifang, 3Graduate School, Taishan...

Longitudinal validity and reliability of the Myeloma Patient Outcome Scale (MyPOS) was established using traditional, generalizability and Rasch psychometric methods

Purpose The Myeloma Patient Outcome Scale (MyPOS) was developed to measure quality of life in routine clinical care. The aim of this study was to determine its longitudinal validity, reliability, responsiveness to change and its acceptability. Methods This 14-centre study recruited patients with multiple myeloma. At baseline and then every two months for 5 assessments, patients...

Elastic–plastic model identification for rock surrounding an underground excavation based on immunized genetic algorithm

To compute the stability of underground engineering, a constitutive model of surrounding rock must be identified. Many constitutive models for rock mass have been proposed. In this model identification study, a generalized constitutive law for an elastic–plastic constitutive model is applied. Using the generalized constitutive law, the problem of model identification is...

Clinicopathological and prognostic significance of sialyl Lewis X overexpression in patients with cancer: a meta-analysis

Clinicopathological and prognostic significance of sialyl Lewis X overexpression in patients with cancer: a meta-analysis Jin-xiao Liang,1 Yong Liang,2 Wei Gao3 1Department of Thoracic Surgery, Zhejiang Cancer Hospital, Hangzhou, People’s Republic of China; 2Department of Clinical Medicine, Taizhou University Medical School, Taizhou, People’s Republic of China; 3School of...

Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor

The microtubule-stabilizing drug epothilone B (epoB) has shown potential value in the treatment of spinal cord injury (SCI) through diverse mechanisms. However, it remains elusive why a limited overall effect was observed. We aim to investigate the limiting factors underlying functional recovery promoted by epoB. The same SCI model treated by epoB was established as discussed...