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Drought stress has transgenerational effects on soybean seed germination and seedling vigor

acquisition: K. Raja Reddy, Wei Gao. Investigation: Chathurika Wijewardana, K. Raja Reddy. Methodology: Chathurika Wijewardana, K. Raja Reddy. Project administration: K. Raja Reddy. Resources: K. Raja Reddy ... Krutz, Wei Gao, Nacer Bellaloui. 18 / 20 19 / 20 1. USDA. Periodic and scheduled ERS publications and data on soybeans and oil crops . United States Department of Agriculture Economic Research Service

On Cyber Attacks and Signature Based Intrusion Detection for Modbus Based Industrial Control Systems

Control Systems," Journal of Digital Forensics, Security and Law: Vol. 9 : No. 1 , - Commons Article 3. (c)ADFSL This work is licensed under a Creative Commons Attribution 4.0 International License. Wei ... Gao Thom as H. Morri s Department of Electrical and Computer Engineering Mississippi State University 1. INTRODUCTION Industrial control systems, also called Supervisory Control and Data

A Critical Appraisal and Recommendations for Cost-Effectiveness Studies of Poly(ADP-Ribose) Polymerase Inhibitors in Advanced Ovarian Cancer

subsidiary of Merck & Co, Inc, Kenilworth, NJ, USA. Dominic Muston, Matthew Monberg, and Elizabeth Szamreta are employees of Merck & Co., Inc.; Wei Gao, Elyse Swallow, Su Zhang, Iden Kalemaj, and James

An Economic Evaluation of Pembrolizumab Versus Other Adjuvant Treatment Strategies for Resected High-Risk Stage III Melanoma in the USA

., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. Conflict of interest Arielle G. Bensimon, Zheng-Yi Zhou, Madeline Jenkins, Yan Song, Wei Gao, and James Signorovitch are employees of Analysis

Parental Environmental Effects on Seed Quality and Germination Response to Temperature of Andropogon gerardii

Chathurika Wijewardana Daryl Chastain Wei Gao Kambham Raja Reddy Parental environments (PEs) a ect seed quality and might alter the re-establishment of big bluestem grass due to impacts on seed germination

A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor

A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor Beibei Wang,1 Sunyi Wu,1 Zhiqiang Lin,2 Yajun Jiang,1 Yan Chen,1 Zhe-Sheng Chen,3 Xiaoying Yang,1 Wei Gao1,4 1Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics...

Human Monoclonal Antibody Targeting the Heparan Sulfate Chains of Glypican-3 Inhibits HGF-Mediated Migration and Motility of Hepatocellular Carcinoma Cells

Heparan sulfate proteoglycans (HSPGs) participate in many processes related to tumor development, including tumorigenesis and metastasis. HSPGs contain one or more heparan sulfate (HS) chains that are covalently linked to a core protein. Glypican-3 (GPC3) is a cell surface-associated HSPG that is highly expressed in hepatocellular carcinoma (HCC). GPC3 is involved in Wnt3a...

Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer

Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer Wei Gao,1 Guihua Ye,1 Xiaochuan Duan,1 ... City (Grant No 15JCZDJC36300). This project is partially supported by the National Science Foundation of China A3 program (Grant 813611403), of which Dr Wei Gao is a participating faculty member

Assessing utility values for treatment-related health states of acute myeloid leukemia in the United States

Preference valuations of health status are essential in health technology and economic appraisal. This study estimated utilities for treatment-related health states of acute myeloid leukemia (AML) and disutilities of severe adverse events (SAEs) using a representative sample of adults from the general population in the United States (US). Treatment-related AML health states...

Novel Immunocytokine IL12-SS1 (Fv) Inhibits Mesothelioma Tumor Growth in Nude Mice

Mesothelin is a glycosylphosphatidylinositol-anchored glycoprotein that is highly expressed on the cell surface of malignant mesothelioma. Monoclonal antibodies against mesothelin are being evaluated for the treatment of mesothelioma. Immunocytokines represent a novel class of armed antibodies. To provide an alternative approach to current mesothelin-targeted antibody therapies...

The regional neuronal activity in left posterior middle temporal gyrus is correlated with the severity of chronic aphasia

The regional neuronal activity in left posterior middle temporal gyrus is correlated with the severity of chronic aphasia Jianlin Li,1,* Dunren Du,2,* Wei Gao,1 Xichun Sun,3 Haizhu Xie,1 Gang Zhang,1

Consistent Anterior–Posterior Segregation of the Insula During the First 2 Years of Life

The human insula is a complex region characterized by heterogeneous cytoarchitecture, connectivity, and function. Subregional parcellation of the insula in adults has revealed an interesting anterior–posterior subdivision pattern that is highly consistent with its functional differentiation. However, the development of the insula's subregional segregation during the first 2 years...

Functional Magnetic Resonance Imaging of Electrical and Optogenetic Deep Brain Stimulation at the Rat Nucleus Accumbens

Deep brain stimulation of the nucleus accumbens (NAc-DBS) is an emerging therapy for diverse, refractory neuropsychiatric diseases. Although DBS therapy is broadly hypothesized to work through large-scale neural modulation, little is known regarding the neural circuits and networks affected by NAc-DBS. Using a healthy, sedated rat model of NAc-DBS, we employed both evoked- and...

Investigating Tissue Optical Properties and Texture Descriptors of the Retina in Patients with Multiple Sclerosis

Purpose To assess the differences in texture descriptors and optical properties of retinal tissue layers in patients with multiple sclerosis (MS) and to evaluate their usefulness in the detection of neurodegenerative changes using optical coherence tomography (OCT) image segmentation. Patients and Methods 38 patients with MS were examined using Stratus OCT. The raw macular OCT...

Comparing baseline and longitudinal measures in association studies

In recent years, longitudinal family-based studies have had success in identifying genetic variants that influence complex traits in genome-wide association studies. In this paper, we suggest that longitudinal analyses may contain valuable information that can enable identification of additional associations compared to baseline analyses. Using Genetic Analysis Workshop 18 data...

Cellular and Subcellular Immunohistochemical Localization and Quantification of Cadmium Ions in Wheat (Triticum aestivum)

The distribution of metallic ions in plant tissues is associated with their toxicity and is important for understanding mechanisms of toxicity tolerance. A quantitative histochemical method can help advance knowledge of cellular and subcellular localization and distribution of heavy metals in plant tissues. An immunohistochemical (IHC) imaging method for cadmium ions (Cd2+) was...

Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment

Using the principle of antibody-drug conjugates that deliver highly potent cytotoxic agents to cancer cells for cancer therapy, we here report the synthesis of antisense-oligonucleotides (ASO) and thyroid hormone T3 conjugates for obesity treatment. ASOs primarily target fat and liver with poor penetrance to other organs. Pharmacological T3 treatment increases energy expenditure...

Detection of Multidecadal Changes in UVB and Total Ozone Concentrations over the Continental US with NASA TOMS Data and USDA Ground-Based Measurements

Thinning of the atmospheric ozone layer leads to elevated levels of Ultraviolet-B (UVB) at the Earth's surface, resulting in an increase of health risks to living organisms due to DNA damage. This paper examines the multidecadal changes of total column ozone from 1979 to 2005 with the aid of ground-based UVB stations using the ultraviolet multifilter rotating shadow-band...