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Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs

, Jonathan Wei Kiat Wee1, Jen Chi Soong1, Damien Chua1, Wei Ren Tan1, Marco Lizwan1, Yinliang Li1, Ziqiang Teo1, Wilson Wen Bin Goh1, Pengcheng Zhu1Email author and Nguan Soon Tan1, 2, 3, 4Email authorView

The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-α Expression in Macrophages

27 July 2017; Accepted 24 January 2018; Published 13 March 2018 Academic Editor: Hao Liu Copyright © 2018 Wei-Ren Shen et al. This is an open access article distributed under the Creative Commons ... precursors or RANKL expression in stromal cells. Conflicts of Interest The authors declare that there is no conflict of interest. Authors’ Contributions Wei-Ren Shen contributed to conception, design, data

Special focus on distributed cooperative analysis, control and optimization in networks

City University of Hong Kong, China Wei REN University of California, Riverside, USA Xinghuo YU RMIT University , Australia Distributed cooperative analysis, control and optimization in networked

Serum uric acid and non-alcoholic fatty liver disease in non-obesity Chinese adults

; SBP: Systolic blood pressure; SD: Standard deviation; SUA: Serum uric acid; TC: Total cholesterol; TG: Triacylglycerol Acknowledgments I hereby express gratitude to my dear Prof. Yonghong Wang, Wei Ren

A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating

Materials Research Laboratory, Key Laboratory of the Ministry of Education & International Center for Dielectric Research, Xi’an Jiaotong University, Xi’an, 710049, ChinaBei Zhao, Wei Ren, Ming Liu & Zuo ... , CanadaZuo-Guang Ye AuthorsSearch for Bei Zhao in:Nature Research journals • PubMed • Google Scholar Search for Xingye Cui in:Nature Research journals • PubMed • Google Scholar Search for Wei Ren in:Nature

Optimum electronic structures for high thermoelectric figure of merit within several isotropic elastic scattering models

for Wei Ren in:Nature Research journals • PubMed • Google Scholar Contributions Y.Y. carried out the calculations and drafted the manuscript; G.Z. and Y.J. participated in the discussion; J.Y. revised ... . Corresponding authors Correspondence to Yuanxu Wang or Wei Ren. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use

Correlation of serum cartilage oligometric matrix protein (COMP) and interleukin-16 (IL-16) levels with disease severity in primary knee osteoarthritis: A pilot study in a Malaysian population

Contributions Conceptualization: Esha Das Gupta, Abdul Kareem Bhurhanudeen, Swan Sim Yeap. Data curation: Wei Ren Ng, Shew Fung Wong. Formal analysis: Esha Das Gupta, Wei Ren Ng, Shew Fung Wong, Swan Sim Yeap ... . Funding acquisition: Esha Das Gupta, Wei Ren Ng, Abdul Kareem Bhurhanudeen. Investigation: Esha Das Gupta, Wei Ren Ng, Shew Fung Wong, Abdul Kareem Bhurhanudeen. Methodology: Esha Das Gupta. Project

JAK2/STAT3 Pathway Was Associated with the Protective Effects of IL-22 On Aortic Dissection with Acute Lung Injury

July 2017 Academic Editor: Stamatios E. Theocharis Copyright © 2017 Wei Ren et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted ... Zhiwei Wang and Zhiyong Wu designed the study. Zhiwei Wang wrote the manuscript. Wei Ren did the experiment. Zhipeng Hu, Feifeng Dai, and Jinxing Chang did the data collection. Bowen Li, Huagang Liu, and

Kangfuxinye Enema Combined with Mesalamine for Ulcerative Colitis: A Systematic Review and GRADE Approach

June 2017; Published 7 August 2017 Academic Editor: Steve Harakeh Copyright © 2017 Peng-wei Ren et al. This is an open access article distributed under the Creative Commons Attribution License, which ... ’ Contributions Guarantor of the article is De-ying Kang. De-ying Kang conceived and designed the review. Peng-wei Ren, Wen-jie Yang, Jing-yan Shan, and Dan-dan Wang conducted literature searches, selected studies

Virtual touch tissue imaging and quantification: value in malignancy prediction for complex cystic and solid breast lesions

This study was aimed to evaluatethe usefulness of conventional ultrasound (US) and US elastography, including the latest virtual touch tissue imaging and quantification (VTIQ), in malignancy prediction for complex cystic and solid breast lesions. Eighty-nine complex cystic and solid breast lesions were subject to conventional US and US elastography, including strain elastography...

Dephosphorylation of Y685-VE-Cadherin Involved in Pulmonary Microvascular Endothelial Barrier Injury Induced by Angiotensin II

Angiotensin II (AngII) caused pulmonary microvascular endothelial barrier injury, which induced acute aortic dissection (AAD) combined with acute lung injury (ALI). However, the exact mechanism is unclear. We investigated the role of dephosphorylation of Y685-VE-cadherin in the AngII induced pulmonary microvascular endothelial barrier injury. Mice or pulmonary microvascular...

Dephosphorylation of Y685-VE-Cadherin Involved in Pulmonary Microvascular Endothelial Barrier Injury Induced by Angiotensin II

Angiotensin II (AngII) caused pulmonary microvascular endothelial barrier injury, which induced acute aortic dissection (AAD) combined with acute lung injury (ALI). However, the exact mechanism is unclear. We investigated the role of dephosphorylation of Y685-VE-cadherin in the AngII induced pulmonary microvascular endothelial barrier injury. Mice or pulmonary microvascular...

LiPISC: A Lightweight and Flexible Method for Privacy-Aware Intersection Set Computation

Privacy-aware intersection set computation (PISC) can be modeled as secure multi-party computation. The basic idea is to compute the intersection of input sets without leaking privacy. Furthermore, PISC should be sufficiently flexible to recommend approximate intersection items. In this paper, we reveal two previously unpublished attacks against PISC, which can be used to reveal...

F2AC: A Lightweight, Fine-Grained, and Flexible Access Control Scheme for File Storage in Mobile Cloud Computing

University of Geosciences, Wuhan 430074, China Received 6 September 2015; Revised 11 November 2015; Accepted 19 November 2015 Academic Editor: Jong-Hyouk Lee Copyright © 2016 Wei Ren et al. This is an open

F2AC: A Lightweight, Fine-Grained, and Flexible Access Control Scheme for File Storage in Mobile Cloud Computing

University of Geosciences, Wuhan 430074, China Received 6 September 2015; Revised 11 November 2015; Accepted 19 November 2015 Academic Editor: Jong-Hyouk Lee Copyright © 2016 Wei Ren et al. This is an open

Cytologically indeterminate thyroid nodules: increased diagnostic performance with combination of US TI-RADS and a new scoring system

-Wen Yue, Le-Hang Guo, Dan Wang, Wei-Wei Ren & Qiao WangThyroid Institute, Tongji University School of Medicine, Shanghai, 200072, ChinaYa-Ping He, Hui-Xiong Xu, Chong-Ke Zhao, Li-Ping Sun, Xiao-Long Li ... , Wen-Wen Yue, Le-Hang Guo, Dan Wang, Wei-Wei Ren, Qiao Wang & Shen QuShanghai Center for Thyroid Diseases, Shanghai, 200072, ChinaYa-Ping He, Hui-Xiong Xu, Chong-Ke Zhao, Li-Ping Sun, Xiao-Long Li, Wen

The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined

Over the past two decades, huge amounts of research were launched to understand the functions of sphingosine. Many pathways were uncovered that convey the relative functions of biomacromolecules. In this review, we discuss the recent advances of the role of the SphKs/S1P/S1PR1 axis in immunity and cancer. Finally, we investigate the therapeutic potential of new drugs that target...

Study of the Binding Energies between Unnatural Amino Acids and Engineered Orthogonal Tyrosyl-tRNA Synthetases

-Riverside, Riverside, California 92521, United StatesTan M. Truong & Hui-wang Ai AuthorsSearch for Wei Ren in:Nature Research journals • PubMed • Google ScholarSearch for Tan M. Truong in:Nature Research