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Outcomes of Stable Multiple Sclerosis Patients Staying on Initial Interferon Beta Therapy Versus Switching to Another Interferon Beta Therapy: A US Claims Database Study

IntroductionThis study was designed to assess real-world outcomes of patients with multiple sclerosis (MS) who were stable on interferon (IFN) beta therapy in the year prior to switching to another IFN beta therapy versus those who continued on the initial treatment.MethodsThis study used administrative claims from MarketScan Commercial Claims and Encounters Database, from...

Seroprevalence of Maternal and Cord Antibodies Specific for Diphtheria, Tetanus, Pertussis, Measles, Mumps and Rubella in Shunyi, Beijing

Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, ChinaQing-hong Meng, Li-jun Li, Wei Shi & Kai-hu YaoDepartment of Neonatology, Beijing Children’s Hospital ... for Wei Shi in:Nature Research journals • PubMed • Google Scholar Search for Ying-jie Shen in:Nature Research journals • PubMed • Google Scholar Search for Li Li in:Nature Research journals • PubMed

Dysregulation of the MiR-449b target TGFBI alters the TGFβ pathway to induce cisplatin resistance in nasopharyngeal carcinoma

AffiliationsPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, CanadaPierre-Antoine Bissey, Jeff P. Bruce, Wei Shi, Melvin L. K. Chua, Kenneth W. Yip & Fei-Fei LiuDepartment of Medical Biophysics ... Scholar Search for Jeff P. Bruce in:Nature Research journals • PubMed • Google Scholar Search for Wei Shi in:Nature Research journals • PubMed • Google Scholar Search for Aline Renoult in:Nature Research

Keyphrase Extraction Using Knowledge Graphs

Extracting keyphrases from documents automatically is an important and interesting task since keyphrases provide a quick summarization for documents. Although lots of efforts have been made on keyphrase extraction, most of the existing methods (the co-occurrence-based methods and the statistic-based methods) do not take semantics into full consideration. The co-occurrence-based...

Hypoxia-Induced Matrix Metalloproteinase-13 Expression in Exosomes from Nasopharyngeal Carcinoma Enhances Metastases

journals • PubMed • Google Scholar Search for Si Shi in:Nature Research journals • PubMed • Google Scholar Search for Wei Shi in:Nature Research journals • PubMed • Google Scholar Search for Zhenxin Zhang

Parametric analysis of occupant ankle and tibia injuries in frontal impact

. Investigation: Wei Shi. Methodology: Xiaoqing Jiang, Zhi Xiao, Sen Xiao. Project administration: Sen Xiao. 8 / 10 Resources: Xiaoqing Jiang, Zhi Xiao. Software: Fuhao Mo, Shuyong Duan. Validation: Xiaoqing ... Jiang, Wei Shi. Visualization: Shuyong Duan, Wei Shi. Writing ± original draft: Sen Xiao. Writing ± review & editing: Fuhao Mo, Shuyong Duan, Zhi Xiao, Sen Xiao. 9 / 10 1. 2009 /2010 Incident Analysis

A continuous 13.3-ka record of seismogenic dust events in lacustrine sediments in the eastern Tibetan Plateau

, Institute of Geology, China Earthquake Administration, Beijing, 100029, ChinaHanchao Jiang, Ning Zhong, Yanhao Li, Hongyan Xu, Wei Shi & Siqi ZhangCollege of Earth Sciences, University of Chinese Academy of ... • PubMed • Google Scholar Search for Xiaolin Ma in:Nature Research journals • PubMed • Google Scholar Search for Hongyan Xu in:Nature Research journals • PubMed • Google Scholar Search for Wei Shi

Designing Efficient Mobile Gateway for Impoverished Regions Based on Self-Learning Strategy

Multiple wireless access technology had tremendously extended the coverage of Internet from developed cities to impoverished regions. As the significant network equipment, mobile gateway had been assigned more and more tasks. However, the efficiency issues are still challenging. Motivated by the latest progress in self-learning, we proposed a new scheme for mobile gateway design...

Optimised Selection of Stroke Biomarker Based on Svm and Information Theory

With the development of molecular biology and gene-engineering technology, gene diagnosis has been an emerging approach for modern life sciences. Biological marker, recognized as the hot topic in the molecular and gene fields, has important values in early diagnosis, malignant tumor stage, treatment and therapeutic efficacy evaluation. So far, the researcher has not found any...

Inducible ATF3–NFAT axis aggravates podocyte injury

Podocyte injury and loss contribute to proteinuria, glomerulosclerosis, and eventually kidney failure. Activating transcription factor 3 (ATF3) is a stress inducible transcription factor that is transiently expressed following stimulation. However, we show for the first time an induction of ATF3 in podocytes from patients with chronic kidney disease, including minimal change...

Effects of temperature and fluid media on the scroll width size of the Descemet’s membrane endothelial keratoplasty (DMEK) donor graft

Effects of temperature and fluid media on the scroll width size of the Descemet's membrane endothelial keratoplasty (DMEK) donor graft Ellen H Koo,1 Allen O Eghrari,2 Ryan S Meshkin,2 Wei Shi,1

Prognostic Value of E-Cadherin and β-Catenin in Triple-Negative Breast Cancer

Objectives: To analyze the expression of E-cadherin and β-catenin in triple-negative breast cancer (TNBC) to assess their prognostic significance.

Generation of an ultra-short electrical pulse with width shorter than the excitation laser

information AffiliationsApplied Physics Department, Xi’an University of Technology, Xi’an, 710048, P. R. ChinaWei Shi, Shaoqiang Wang, Cheng Ma & Ming Xu AuthorsSearch for Wei Shi in:Nature Research journals ... Correspondence to Wei Shi. Supplementary information PDF files1.Supplementary Information Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International License. The

Research on Medicine Distribution Route Optimization for Community Health Service Institutions

At present, the optimization of medicine distribution route has become an urgent issue that needs to be solved in the unified medicine distribution for community health service institutions. Considering the characteristics of medicine distribution for community health service institutions, to minimize the overall cost (including refrigeration storage cost, vehicle fixed cost, and...

Rapid Quantification of Melamine in Different Brands/Types of Milk Powders Using Standard Addition Net Analyte Signal and Near-Infrared Spectroscopy

Bang-Cheng Tang, Chen-Bo Cai, Wei Shi, and Lu Xu declare no competing interests. Acknowledgments The authors are grateful to the financial support from the Research Projects of Guizhou Science and

Identification of unique B virus (Macacine Herpesvirus 1) epitopes of zoonotic and macaque isolates using monoclonal antibodies

Contributions Conceptualization: David Katz, Julia K. Hilliard. Data curation: David Katz, Wei Shi, Manjunath S. Gowda, Mugdha Vasireddi, Irina Patrusheva, Hyuk-Kyu Seoh, Chadi N. Filfili, Martin J. Wildes, Jay ... Oh, Julia K. Hilliard. Formal analysis: David Katz, Wei Shi, Manjunath S. Gowda, Irina Patrusheva, Hyuk-Kyu Seoh, Julia K. Hilliard. Funding acquisition: David Katz. Investigation: David Katz, Wei

Mining Software Repositories for Automatic Interface Recommendation

There are a large number of open source projects in software repositories for developers to reuse. During software development and maintenance, developers can leverage good interfaces in these open source projects and establish the framework of the new project quickly when reusing interfaces in these open source projects. However, if developers want to reuse them, they need to...

Comparative Effectiveness Research of Disease-Modifying Therapies for the Management of Multiple Sclerosis: Analysis of a Large Health Insurance Claims Database

employee of Biogen at the time of the study. Wei-Shi Yeh was an employee of Biogen at the time of the study. Monica Fay is an employee of, and holds stock and/or stock options in, Biogen. Michael Edwards

Can GSTM1 and GSTT1 polymorphisms predict clinical outcomes of chemotherapy in gastric and colorectal cancers? A result based on the previous reports

Can GSTM1 and GSTT1 polymorphisms predict clinical outcomes of chemotherapy in gastric and colorectal cancers? A result based on the previous reports Haixia Liu,1,* Wei Shi,2,* Lianli Zhao,3 Dianlu

Managed honeybee colony losses of the Eastern honeybee (Apis cerana) in China (2011–2014)

Colony losses of managed honeybees have raised a major concern, and surveys of colony losses were conducted around the globe to understand the apicultural situation. Up to now, most studies have focused on the mortality of the Western honeybee (Apis mellifera); however, little is known about the mortality of its eastern counterpart—the Eastern honeybee (Apis cerana). Here, we...