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Pre-computed Region Guardian Sets Based Reverse kNN Queries

all existed algorithms. Acknowledgements Research of Wei Wang is supported by ARC DP130103401 and DP130103405. Muhammad Aamir Cheema is supported by ARC DE130101002 and DP130103405. Open Access This

Porous yet dense metal-free electro-materials for compact energy storage

Metal-free electro-materials, made of mainly conjugated carbon atoms as well as other elements, allow the development of abundant porosity and good conductivity. Most importantly, metal-free electro-materials are preferential in terms of sustainability, chemical variety and processability. Nevertheless the challenge of using metal-free materials is to increase the density. ...

Integration of suboptimal health status and endothelial dysfunction as a new aspect for risk evaluation of cardiovascular disease

Background Suboptimal health status (SHS) is recognized as a subclinical, reversible stage of chronic disease. Association has been confirmed between SHS and cardiovascular risk factors, indicating that SHS may contribute to the development of cardiovascular disease. This study explored integrated risk assessment of cardiovascular disease by combining SHS questionnaire-25 (SHSQ-25) ...

First report of Rickettsia raoultii and R. slovaca in Melophagus ovinus, the sheep ked

Wang 4 Chang-Chun Tu 3 Chuang-Fu Chen 0 0 College of Animal Science and Technology, Shihezi University , Shihezi, Xinjiang Uygur Autonomous Region 832002 , China 1 Institute of Veterinary Medicine

China suboptimal health cohort study: rationale, design and baseline characteristics

Background Suboptimal health status (SHS) is a physical state between health and disease, characterized by the perception of health complaints, general weakness, chronic fatigue and low energy levels. SHS is proposed by the ancient concept of traditional Chinese medicine (TCM) from the perspective of preservative, predictive and personalized (precision) medicine. We previously ...

Traditional Chinese medicine and new concepts of predictive, preventive and personalized medicine in diagnosis and treatment of suboptimal health

Background The premise of disease-related phenotypes is the definition of the counterpart normality in medical sciences. Contrary to clinical practices that can be carefully planned according to clinical needs, heterogeneity and uncontrollability is the essence of humans in carrying out health studies. Full characterization of consistent phenotypes that define the general ...

Long-term effect of respiratory training for chronic obstructive pulmonary disease patients at an outpatient clinic: a randomised controlled trial

Objective To assess the effect of respiratory training (RT) on lung function, activity tolerance and acute exacerbation frequency with chronic obstructive pulmonary disease (COPD). Design A randomised controlled trial. Setting Outpatient clinic and home of the COPD patients, Zhengzhou City, China. Subjects Sixty participants with COPD were randomised into two groups: an ...

Range expansion and habitat shift triggered elevated diversification of the rice genus (Oryza, Poaceae) during the Pleistocene

Background The rice genus (Oryza) contains many wild genetic resources that are vital to the well-being of humans. However, little is known about the process by which the genus diversified or the factors that drove its speciation. Here, we integrated the phylogenetic, molecular dating and biogeographic methods to investigate the spatial-temporal patterns of Oryza diversification, ...

Spatiotemporal Cluster Patterns of Hand, Foot, and Mouth Disease at the County Level in Mainland China, 2008-2012

Background Hand, foot, and mouth disease (HFMD) is known to be a highly contagious childhood illness. In recent years, the number of reported cases of HFMD has significantly increased in mainland China. This study aims at the epidemiological features, spatiotemporal patterns of HMFD at the county/district level in mainland China. Methods Data on reported HFMD cases for each county ...

Impacts of Different Grades of Tropical Cyclones on Infectious Diarrhea in Guangdong, 2005-2011

Objective Guangdong province is one of the most vulnerable provinces to tropical cyclones in China. Most prior studies concentrated on the relationship between tropical cyclones and injuries and mortality. This study aimed to explore the impacts of different grades of tropical cyclones on infectious diarrhea incidence in Guangdong province, from 2005 to 2011. Methods Mann-Whitney U ...

Suboptimal health: a new health dimension for translational medicine

Background One critical premise of disease-related biomarkers is the definition of the counterpart normality. Contrary to pre-clinical models that can be carefully tailored according to scientific need, heterogeneity and uncontrollability is the essence of humans in health studies. Fully characterization of consistent parameters that define the normal population is the basis to ...

PM2.5 Spatiotemporal Variations and the Relationship with Meteorological Factors during 2013-2014 in Beijing, China

Objective Limited information is available regarding spatiotemporal variations of particles with median aerodynamic diameter < 2.5 μm (PM2.5) at high resolutions, and their relationships with meteorological factors in Beijing, China. This study aimed to detect spatiotemporal change patterns of PM2.5 from August 2013 to July 2014 in Beijing, and to assess the relationship between ...

Characterization of PERV in a new conserved pig herd as potential donor animals for xenotransplantation in China

Background Xenotransplantation has drawn increased attention in recent years as a potential solution to the scarcity of human source donor organs. Researchers have highlighted the need to characterize the influence of porcine endogenous retroviruses (PERV) in xenotransplantation. Screening and analyzing the presence and subtype of PERV in donor source animal breeds could provide ...

Prevalence and risk factors for cervical neoplasia: a cervical cancer screening program in Beijing

Background Cervical cancer is the second most common cancer and cause of cancer-related death for women worldwide. The aims of this study were to investigate the prevalence of cervical neoplasia and examine factors associated with high-grade cervical squamous intraepithelial lesions (HSIL) among women taking part in a cervical cancer screening program in Beijing. Methods Women aged ...