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Visual hallucinations in Alzheimer's disease is significantly associated with clinical diagnostic features of dementia with Lewy bodies

statistical analyses. Author Contributions Conceptualization: Pai-Yi Chiu, Ming-Chyi Pai. Data curation: Pai-Yi Chiu, Chein-Wei Wang, Chun-Tang Tsai. Formal analysis: Pai-Yi Chiu. Investigation: Pai-Yi ... Chiu. Methodology: Pai-Yi Chiu, Min-Hsien Hsu, Chein-Wei Wang, Chun-Tang Tsai, Ming-Chyi Pai. Project administration: Pai-Yi Chiu. Resources: Pai-Yi Chiu, Ming-Chyi Pai. Software: Pai-Yi Chiu, Min

Depression in dementia with Lewy bodies: A comparison with Alzheimer's disease

Background Depression is highly associated with dementia, and this study will compare the frequencies, severity, and symptoms of depression between dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD). Methods Frequency of depression was determined according to the DSM-IV criteria for major depression or the National Institute of Mental Health criteria for depression in AD ...

Dysregulation of endothelial colony-forming cell function by a negative feedback loop of circulating miR-146a and -146b in cardiovascular disease patients

CAD ECFCs (RPM > 5 and > 3-fold change). (TIF) Acknowledgments This paper is dedicated to the memory of Dr. Hsei-Wei Wang, April 1969~Sep 2015. We thank Dr. Pei-Ching Chang (National Yang-Ming ... : Ting-Yu Chang, Shu-Meng Cheng, Hsei-Wei Wang. Data curation: Ting-Yu Chang, Tse-Shun Huang. Formal analysis: Ting-Yu Chang, Tse-Shun Huang. Funding acquisition: Wei-Chi Tsai, Chun-Hsien Wu, Cheng

Association of eNOS and Cav-1 gene polymorphisms with susceptibility risk of large artery atherosclerotic stroke

Endothelial nitric oxide synthase (eNOS) is localized in caveole and has important effects on caveolar coordination through its interaction with caveolin-1 (Cav-1), which supports normal functioning of vascular endothelial cells. However, the relationship between genotypic polymorphisms of e-NOS and Cav-1 genes and ischemic stroke (IS) remains lesser reported. This hospital-based ...

Association between complicated liver cirrhosis and the risk of hepatocellular carcinoma in Taiwan

Chuah. Project administration: Chih-Ming Liang, Ming-Kun Ku, Pin-I Hsu. Resources: Kai-Lung Tsai, Ming-Kun Ku, Jiunn-Wei Wang, Pin-I Hsu, Seng-Kee Chuah. Software: Kai-Lung Tsai, Ming-Kun Ku, Jiunn-Wei ... Wang, Shih-Cheng Yang. Supervision: Deng-Chyang Wu, Seng-Kee Chuah. Validation: Jiunn-Wei Wang. Visualization: Jiunn-Wei Wang, Shih-Cheng Yang. Writing ± original draft: Tsung-Hsing Hung. Writing

Tumor Necrosis Factor-Alpha and the ERK Pathway Drive Chemerin Expression in Response to Hypoxia in Cultured Human Coronary Artery Endothelial Cells

Background Chemerin, a novel adipokine, plays a role in the inflammation status of vascular endothelial cells. Hypoxia causes endothelial-cell proliferation, migration, and angiogenesis. This study was aimed at evaluating the protein and mRNA expression of chemerin after exposure of human coronary artery endothelial cells (HCAECs) to hypoxia. Methods and Results Cultured HCAECs ...

Analysis of opportunistic spectrum access in cognitive radio networks using hidden Markov model with state prediction

Jyu-Wei Wang 0 Ramzi Adriman 1 0 Department of Photonics and Comm. Engineering, Asia University , No. 500, Lioufong Rd., Wufong District, Taichung City , Taiwan 1 Department of Computer Science

Combination Therapy Using Chelating Agent and Zinc for Wilson’s Disease

There is no clear international consensus regarding the optimal medication therapy for treating Wilson’s disease (WD). This study systematically reviews the effectiveness of various medication therapies in common use, specifically focusing on preliminary findings concerning the combination of a chelating agent and zinc. A systematic PubMed search was executed to locate original ...

The Role of Adjuvant Acid Suppression on the Outcomes of Bleeding Esophageal Varices after Endoscopic Variceal Ligation

The impact of adjuvant acid suppression via proton pump inhibitors or histamine-2 receptor antagonists after endoscopic variceal ligation remains uncertain. We therefore aimed to evaluate the effect of adjuvant acid suppression on the rebleeding and mortality rates in patients who received endoscopic variceal ligation and vasoconstrictor therapy for bleeding esophageal varices. ...

Mechanical Stretch Inhibits MicroRNA499 via p53 to Regulate Calcineurin-A Expression in Rat Cardiomyocytes

Background MicroRNAs play an important role in cardiac remodeling. MicroRNA 499 (miR499) is highly enriched in cardiomyocytes and targets the gene for Calcineurin A (CnA), which is associated with mitochondrial fission and apoptosis. The mechanism regulating miR499 in stretched cardiomyocytes and in volume overloaded heart is unclear. We sought to investigate the mechanism ...

Risk of Rebleeding and Mortality in Cirrhotic Patients with Peptic Ulcer Bleeding: A 12-Year Nationwide Cohort Study

Although a few studies have investigated the risks of peptic ulcer bleeding (PUB) in cirrhotic patients, large population-based studies on in-hospital and long-term reports on recurrent PUB in a cohort of cirrhotic patients are lacking. This 12-year nationwide cohort study aimed to investigate the risks of in-hospital and long-term rebleeding and mortality in cirrhotic patients and ...

Community Structure of Macrobiota and Environmental Parameters in Shallow Water Hydrothermal Vents off Kueishan Island, Taiwan

Hydrothermal vents represent a unique habitat in the marine ecosystem characterized with high water temperature and toxic acidic chemistry. Vents are distributed at depths ranging from a few meters to several thousand meters. The biological communities of shallow-water vents have, however, been insufficiently studied in most biogeographic areas. We attempted to characterize the ...

Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells

Background Leptin, produced mainly by white adipose tissue, is a hormone that promotes vascular smooth muscle cell (VSMC) migration and proliferation, a process involved in the pathophysiology of atherosclerosis. Leptin expression in human coronary artery smooth cell (HCASMC) is induced by hypoxia. However, our understanding of the process of atherosclerosis in HCASMC is only ...

Clinicopathological characteristics and outcomes in stage I–III mucinous gastric adenocarcinoma: a retrospective study at a single medical center

Background The clinicopathological characteristics and outcomes of mucinous gastric adenocarcinoma (GC) remain unclear. We report the clinicopathological features and prognosis of patients with mucinous histology who underwent radical-intent gastrectomy. Methods We reviewed the medical records of 1470 patients with pathologically proven undifferentiated GC undergoing radical-intent ...

Comparison of Standing Posture Bioelectrical Impedance Analysis with DXA for Body Composition in a Large, Healthy Chinese Population

Bioelectrical impedance analysis (BIA) is a common method for assessing body composition in research and clinical trials. BIA is convenient but when compared with other reference methods, the results have been inconclusive. The level of obesity degree in subjects is considered to be an important factor affecting the accuracy of the measurements. A total of 711 participants were ...

Predicting Neuroinflammation in Morphine Tolerance for Tolerance Therapy from Immunostaining Images of Rat Spinal Cord

Long-term morphine treatment leads to tolerance which attenuates analgesic effect and hampers clinical utilization. Recent studies have sought to reveal the mechanism of opioid receptors and neuroinflammation by observing morphological changes of cells in the rat spinal cord. This work proposes a high-content screening (HCS) based computational method, HCS-Morph, for predicting ...

The Association of Helicobacter pylori Eradication with the Occurrences of Chronic Kidney Diseases in Patients with Peptic Ulcer Diseases

The association of Helicobacter pylori eradication with the occurrence of renal dysfunction in patients with peptic ulcer diseases is still unclear. This study aimed to clarify the relevance of H. pylori eradication to the occurrence of chronic kidney diseases in patients with peptic ulcer diseases. Data that were available from 2000–2011 were extracted from the National Health ...

Mechanical Stretch Induces Apoptosis Regulator TRB3 in Cultured Cardiomyocytes and Volume-Overloaded Heart

The expression of TRB3 (tribbles 3), an apoptosis regulated gene, increases during endoplasmic reticulum (ER) stress. How mechanical stress affects the regulation of TRB3 in cardiomyocytes during apoptosis is not fully understood. An in vivo model of aorta-caval shunt in adult rats demonstrated the increased TRB3 protein expression in the myocardium. The tumor necrosis factor-alpha ...