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261 papers found.
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MEFV M694V mutation has a role in susceptibility to ankylosing spondylitis: A meta-analysis

researchers (Linqing Zhong and Wei Wang): 1) characteristics of included studies, i.e., the title, the first author, publication year, sample size, study population, and genotyping methods; and 2) the ... researcher (Hongmei Song). Quality assessment The two researchers (Linqing Zhong and Wei Wang) independently evaluated the qualities of the included studies with the Newcastle Ottawa Scale (NOS) [28]. The

Editorial: Mobile Multimedia Communications

Shaanxi Province, China in 2011; and SisuAward, Nokia Research Center, Helsinki in 2010. She is a senior member of IEEE. Wei Wang (M’10 – SM’16) received the Ph.D. degree in computer engineering from the

Robust group compressive sensing for DOA estimation with partially distorted observations

In this paper, we propose a robust direction-of-arrival (DOA) estimation algorithm based on group sparse reconstruction algorithm utilizing signals observed at multiple frequencies. The group sparse reconstruction scheme for DOA estimation is solved through the complex multitask Bayesian compressive sensing algorithm by exploiting the group sparse property of the received ...

Dysregulation of endothelial colony-forming cell function by a negative feedback loop of circulating miR-146a and -146b in cardiovascular disease patients

CAD ECFCs (RPM > 5 and > 3-fold change). (TIF) Acknowledgments This paper is dedicated to the memory of Dr. Hsei-Wei Wang, April 1969~Sep 2015. We thank Dr. Pei-Ching Chang (National Yang-Ming ... : Ting-Yu Chang, Shu-Meng Cheng, Hsei-Wei Wang. Data curation: Ting-Yu Chang, Tse-Shun Huang. Formal analysis: Ting-Yu Chang, Tse-Shun Huang. Funding acquisition: Wei-Chi Tsai, Chun-Hsien Wu, Cheng

Determination of influenza B identity and potency in quadrivalent inactivated influenza vaccines using lineage-specific monoclonal antibodies

Co-circulation of two antigenically and genetically distinct lineages of influenza B virus, represented by prototype viruses B/Victoria/2/1987 and B/Yamagata/16/1988, has led to the development of quadrivalent influenza vaccines that contain two influenza B antigens. The inclusion of two influenza B antigens presents challenges for the production and regulation of inactivated ...

Special issue on resilience in steel structures

Structures”. Guest Editors Wei Wang Professor, Tongji University, China E-mail: Tak-Ming Chan Assistant Professor, The Hong Kong Polytechnic University, Hong Kong SAR, China Yunfeng Zhang Professor, University

Facing the challenges in ophthalmology clerkship teaching: Is flipped classroom the answer?

Recent reform of medical education highlights the growing concerns about the capability of the current educational model to equip medical school students with essential skills for future career development. In the field of ophthalmology, although many attempts have been made to address the problem of the decreasing teaching time and the increasing load of course content, a growing ...

Challenges for strengthening the health workforce in the Lao People’s Democratic Republic: perspectives from key stakeholders

Background The Lao People’s Democratic Republic is facing a critical shortage and maldistribution of health workers. Strengthening of the health workforce has been adopted as one of the five priorities of the National Health Sector Strategy (2013–2025). This study aims to identify, explore, and better understand the key challenges for strengthening the Laotian health workforce. ...

Human perception of electrical stimulation on the surface of somatosensory cortex

Recent advancement in electrocorticography (ECoG)-based brain-computer interface technology has sparked a new interest in providing somatosensory feedback using ECoG electrodes, i.e., cortical surface electrodes. We conducted a 28-day study of cortical surface stimulation in an individual with arm paralysis due to brachial plexus injury to examine the sensation produced by ...

Sphingolipids Are Required for Efficient Triacylglycerol Loss in Conjugated Linoleic Acid Treated Adipocytes

Conjugated linoleic acid (CLA) reduces adiposity in human and mouse adipocytes. This outcome is achieved through a variety of biological responses including increased energy expenditure and fatty acid oxidation, increased inflammation, repression of fatty acid biosynthesis, attenuated glucose transport, and apoptosis. In the current study, profiling of 261 metabolites was conducted ...

Sparse regression models for unraveling group and individual associations in eQTL mapping

Background As a promising tool for dissecting the genetic basis of common diseases, expression quantitative trait loci (eQTL) study has attracted increasing research interest. Traditional eQTL methods focus on testing the associations between individual single-nucleotide polymorphisms (SNPs) and gene expression traits. A major drawback of this approach is that it cannot model the ...

Validation of standard operating procedures in a multicenter retrospective study to identify -omics biomarkers for chronic low back pain

Chronic low back pain (CLBP) is one of the most common medical conditions, ranking as the greatest contributor to global disability and accounting for huge societal costs based on the Global Burden of Disease 2010 study. Large genetic and -omics studies provide a promising avenue for the screening, development and validation of biomarkers useful for personalized diagnosis and ...

FastHap: fast and accurate single individual haplotype reconstruction using fuzzy conflict graphs

Motivation: Understanding exact structure of an individual’s haplotype plays a significant role in various fields of human genetics. Despite tremendous research effort in recent years, fast and accurate haplotype reconstruction remains as an active research topic, mainly owing to the computational challenges involved. Existing haplotype assembly algorithms focus primarily on ...

The Role of p-STAT3 as a Prognostic and Clinicopathological Marker in Colorectal Cancer: A Systematic Review and Meta-Analysis

Objective High expression of phosphorylated signal transducer and activator of transcription 3 (p-STAT3) has been detected in a variety of human tumors. However, the association of positive p-STAT3 expression with clinicopathological parameters and the prognosis of colorectal cancer patients remain controversial. To identify the relationship between p-STAT3 expression and ...

RNA-Skim: a rapid method for RNA-Seq quantification at transcript level

Zhaojun Zhang 1 Wei Wang 0 0 Department of Computer Science, University of California , Los Angeles, CA, USA 1 Department of Computer Science, University of North Carolina at Chapel Hill , Chapel

Collapsing singletons may boost signal for associating rare variants in sequencing study

Advances in next-generation sequencing technology have made it possible to comprehensively interrogate the entire spectrum of genomic variations including rare variants. They may help capture the remaining genetic heritability which has not been fully explained by previous genome-wide association studies. Here we performed a gene-based genome-wide scan to identify hypertension ...

Robust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric Modulators

W1282X is a common nonsense mutation among cystic fibrosis patients that results in the production of a truncated Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channel. Here we show that the channel activity of the W1282X-CFTR polypeptide is exceptionally low in excised membrane patches at normally saturating doses of ATP and PKA (single channel open probability (PO) ...

β-Cyclodextrin-Based Inclusion Complexation Bridged Biodegradable Self-Assembly Macromolecular Micelle for the Delivery of Paclitaxel

In this study, a novel adamantanamine-paclitaxel (AD-PTX) incorporated oligochitosan- carboxymethyl-β-cyclodextrin (CSO-g-CM-β-CD) self-assembly macromolecular (CSO-g-CM-β-CD@AD-PTX) micelle was successfully prepared in water through sonication. The formed molecules were characterized by Fourier transform infrared spectroscopy, proton nuclear magnetic resonance (NMR) spectroscopy, ...