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Range-azimuth decouple beamforming for frequency diverse array with Costas-sequence modulated frequency offsets

Different from the phased-array using the same carrier frequency for each transmit element, the frequency diverse array (FDA) uses a small frequency offset across the array elements to produce range-angle-dependent transmit beampattern. FDA radar provides new application capabilities and potentials due to its range-dependent transmit array beampattern, but the FDA using linearly ...

Modulation of APOE and SORL1 genes on hippocampal functional connectivity in healthy young adults

Apolipoprotein E (APOE) and sortilin-related receptor (SORL1) genes act on the same metabolic pathway and have been associated with Alzheimer’s disease (AD) characterized by hippocampal impairment. Although the effects of APOE on hippocampal resting-state functional connectivity (rsFC) have been reported, the main effects of SORL1 and SORL1 × APOE interactions on hippocampal rsFC ...

Different spatial patterns of brain atrophy and global functional connectivity impairments in major depressive disorder

Alterations in grey matter structure and functional connectivity (FC) are pathological features of major depressive disorder (MDD). However, the relationship between brain structural and functional impairments in MDD remains uncertain. Thus, the aim of this study was to investigate the relationship between alterations in grey matter volume (GMV) and resting-state global functional ...

Fumarate Production by Torulopsis glabrata: Engineering Heterologous Fumarase Expression and Improving Acid Tolerance

Fumarate is a well-known biomass building block compound. However, the poor catalytic efficiency of fumarase is one of the major factors preventing its widespread production. To address this issue, we selected residues 159HPND162 of fumarase from Rhizopus oryzae as targets for site-directed mutagenesis based on molecular docking analysis. Twelve mutants were generated and ...

Subarray-based FDA radar to counteract deceptive ECM signals

, W-Q Wang , Impacts of frequency increment errors on frequency diverse array beampattern . EURASIP J. Adv. Signal Process . 2015 ( 1 ), 1 - 12 ( 2015 ) 31. W Wen-Qin , HC So , H Shao, Nonuniform ... frequency diverse array for range-angle imaging of targets . IEEE Sensors J . 14 ( 8 ), 2469 - 2476 ( 2014 ) 32. H Shao, J Dai, J Xiong, H Chen, W Wen-Qin , Dot-shaped range-angle Beampattern synthesis for

Transponder-Aided Joint Calibration and Synchronization Compensation for Distributed Radar Systems

High-precision radiometric calibration and synchronization compensation must be provided for distributed radar system due to separate transmitters and receivers. This paper proposes a transponder-aided joint radiometric calibration, motion compensation and synchronization for distributed radar remote sensing. As the transponder signal can be separated from the normal radar returns, ...

Interactions of genetic variants reveal inverse modulation patterns of dopamine system on brain gray matter volume and resting-state functional connectivity in healthy young adults

Different genotypic combinations of COMT and DRD2 can generate multiple subgroups with different levels of dopamine signaling. Its modulations on brain properties can be investigated by analyzing the combined gene effects of COMT and DRD2. However, the inherent association between modulation patterns of the dopamine system on structural and functional properties of the brain ...

Impacts of frequency increment errors on frequency diverse array beampattern

Different from conventional phased array, which provides only angle-dependent beampattern, frequency diverse array (FDA) employs a small frequency increment across the antenna elements and thus results in a range angle-dependent beampattern. However, due to imperfect electronic devices, it is difficult to ensure accurate frequency increments, and consequently, the array performance ...

Abnormality of the Corpus Callosum in Coalmine Gas Explosion-Related Posttraumatic Stress Disorder

Abnormal corpus callosum (CC) has been reported in childhood trauma-related posttraumatic stress disorder (PTSD); however, the nature of white matter (WM) integrity alterations in the CC of young adult-onset PTSD patients is unknown. In this study, 14 victims of a coal mine gas explosion with PTSD and 23 matched coal miners without experiencing the coal mine explosion were ...

The Selective Impairment of Resting-State Functional Connectivity of the Lateral Subregion of the Frontal Pole in Schizophrenia

Objective Although extensive resting-state functional connectivity (rsFC) changes have been reported in schizophrenia, rsFC changes of the frontal pole (FP) remain unclear. The FP contains several subregions with different connection patterns; however, it is unknown whether the FP subregions are differentially affected in schizophrenia. To explore this possibility, we compared rsFC ...

Moving Target Indication via Three-Antenna SAR with Simplified Fractional Fourier Transform

Ground moving target indiction (GMTI) is of great important for surveillance and reconnaissance, but it is not an easy job. One technique is the along-track interferometry (ATI) synthetic aperture radar (SAR), which was initially proposed for estimating the radial velocity of ground moving targets. However, the measured differential phase may be contaminated by overlapping ...

Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability

Protein translation is an essential cellular process initiated by the association of a methionyl–tRNA with the translation initiation factor eIF2. The Met-tRNA/eIF2 complex then associates with the small ribosomal subunit, other translation factors and mRNA, which together comprise the translational initiation complex. This process is regulated by the phosphorylation status of the ...

Structural Impairments of Hippocampus in Coal Mine Gas Explosion-Related Posttraumatic Stress Disorder

Investigations on hippocampal and amygdalar volume have revealed inconsistent results in patients with posttraumatic stress disorder (PTSD). Little is known about the structural covariance alterations between the hippocampus and amygdala in PTSD. In this study, we evaluated the alteration in the hippocampal and amygdalar volume and their structural covariance in the coal mine gas ...

A comparison of supracostal and infracostal access approaches in treating renal and upper ureteral stones using MPCNL with the aid of a patented system

Background There are still disagreements on which is a better approach to choose to establish percutaneous tract for percutaneous nephrolitotomy (PCNL), between supracostal and infracostal approaches. The aim of this study is to investigate the safety, efficacy and practicability of minimally invasive PCNL (MPCNL) with the aid of a patented system either through supracostal or ...

Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancer

Yu-Wen Cao 0 Wen-Qin Li 0 Guo-Xing Wan Yi-Xiao Li Xiao-Ming Du Yu-Cong Li Feng Li 0 Equal contributors Department of Pathology and Key Laboratory of Xinjiang Endemic and Ethnic Diseases (Ministry of

Establishment of an efficient transformation protocol and its application in marine-derived Bacillus strain

Marine-derived Bacillus strains have been proved to be a very promising source for natural product leads. However, transformation of environmental strains is much more difficult than that of domesticated strains. Here, we report the development of an efficient and robust electroporation-based transformation system for marine-derived Bacillus marinus B-9987, which is a macrolactin ...

Anatomy and transcript profiling of gynoecium development in female sterile Brassica napus mediated by one alien chromosome from Orychophragmus violaceus

Background The gynoecium is one of the most complex organs of angiosperms specialized for seed production and dispersal, but only several genes important for ovule or embryo sac development were identified by using female sterile mutants. The female sterility in oilseed rape (Brassica napus) was before found to be related with one alien chromosome from another crucifer ...

Contribution of the Resting-State Functional Connectivity of the Contralesional Primary Sensorimotor Cortex to Motor Recovery after Subcortical Stroke

It remains uncertain if the contralesional primary sensorimotor cortex (CL_PSMC) contributes to motor recovery after stroke. Here we investigated longitudinal changes in the resting-state functional connectivity (rsFC) of the CL_PSMC and their association with motor recovery. Thirteen patients who had experienced subcortical stroke underwent a series of resting-state fMRI and ...

The Development of Visual Areas Depends Differently on Visual Experience

Visual experience plays an important role in the development of the visual cortex; however, recent functional imaging studies have shown that the functional organization is preserved in several higher-tier visual areas in congenitally blind subjects, indicating that maturation of visual areas depend unequally on visual experience. In this study, we aim to validate this hypothesis ...

Catechol-O-Methyltransferase Val158Met Polymorphism Modulates Gray Matter Volume and Functional Connectivity of the Default Mode Network

The effect of catechol-O-methyltransferase (COMT) Val158Met polymorphism on brain structure and function has been previously investigated separately and regionally; this prevents us from obtaining a full picture of the effect of this gene variant. Additionally, gender difference must not be overlooked because estrogen exerts an interfering effect on COMT activity. We examined 323 ...