Background The ability to demonstrate the reproducibility of gene expression microarray results is a critical consideration for the use of microarray technology in clinical applications. While studies have asserted that microarray data can be "highly reproducible" under given conditions, there is little ability to quantitatively compare amongst the various metrics and terminology...
Background DNA hypermethylation events and other epimutations occur in many neoplasms, producing gene expression changes that contribute to neoplastic transformation, tumorigenesis, and tumor behavior. Some human cancers exhibit a hypermethylator phenotype, characterized by concurrent DNA methylation-dependent silencing of multiple genes. To determine if a hypermethylation defect...
DNA hypermethylation events and other epimutations occur in many neoplasms, producing gene expression changes that contribute to neoplastic transformation, tumorigenesis, and tumor behavior. Some human cancers exhibit a hypermethylator phenotype, characterized by concurrent DNA methylation-dependent silencing of multiple genes. To determine if a hypermethylation defect occurs in...
During the last several years, high-density genotyping SNP arrays have facilitated genome-wide association studies (GWAS) that successfully identified common genetic variants associated with a variety of phenotypes. However, each of the identified genetic variants only explains a very small fraction of the underlying genetic contribution to the studied phenotypic trait. Moreover...
8 Lee Lancashire 9 Wenjun Bao 10 Tingting Du 5 Heng Luo 5 Zhenqiang Su 6 Wendell D. Jones 11 Carrie L. Moland 6 William S. Branham 6 Feng Qian 6 Baitang Ning 6 Yan Li 6 Huixiao Hong 6 Lei Guo 6 Nan
Leming Shi Wendell D Jones Roderick V Jensen Stephen C Harris Roger G Perkins Federico M Goodsaid Lei Guo Lisa J Croner Cecilie Boysen Hong Fang Feng Qian Shashi Amur Wenjun Bao Catalin C
, Urbana, IL, 61801, USASheng Zhong AuthorsSearch for Leming Shi in:PubMed • Google Scholar Search for Wendell D Jones in:PubMed • Google Scholar Search for Roderick V Jensen in:PubMed • Google Scholar
