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Search: authors:"Willemijne A. M. E. Schrijver"

4 papers found.
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Progressive APOBEC3B mRNA expression in distant breast cancer metastases

Background APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expression is associated with poor prognosis. However, its expression in breast cancer...

Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer

. Schrijver Anieta M. Sieuwerts Maxime P. Look Angelique C. J. Ziel - van der Made Vanja de Weerd John W. Martens Paul J. van Diest Marion de Jong 0 Carolien H. M. van Deurzen Rajeev Samant, University of

The prognostic effect of DDX3 upregulation in distant breast cancer metastases

Metastatic breast cancer remains one of the leading causes of death in women and identification of novel treatment targets is therefore warranted. Functional studies showed that the RNA helicase DDX3 promotes metastasis, but DDX3 expression was never studied in patient samples of metastatic cancer. In order to validate previous functional studies and to evaluate DDX3 as a...

Promoter hypermethylation profiling of distant breast cancer metastases

0 Willemijne A. M. E. Schrijver 1 Department of Pathology, University Medical Center Utrecht , Heidelberglaan 100, 3584 Utrecht, CX , The Netherlands Promoter hypermethylation of tumor suppressor