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Intraoperative ventilatory leak predicts prolonged air leak after lung resection: A retrospective observational study

for the present study. (DOC) S1 File. A dataset for the present study. (XLSX) Author Contributions Conceptualization: Chul-Woo Jung. Data curation: Won Ho Kim, Chul-Woo Jung. Formal analysis: Won Ho ... Kim, Chul-Woo Jung. Investigation: Hyung-Chul Lee, Hyun-Kyu Yoon. 9 / 11 Methodology: Won Ho Kim, Chul-Woo Jung. Project administration: Chul-Woo Jung. Resources: Chul-Woo Jung. Software: Chul-Woo

Preoperative aspirin use and acute kidney injury after cardiac surgery: A propensity-score matched observational study

Background The association between preoperative aspirin use and postoperative acute kidney injury (AKI) in cardiovascular surgery is unclear. We sought to evaluate the effect of preoperative aspirin use on postoperative AKI in cardiac surgery. Methods A total of 770 patients who underwent cardiovascular surgery under cardiopulmonary bypass were reviewed. Perioperative clinical...

Does a Pre-Training Program Influence Colonoscopy Proficiency during Fellowship?

Objectives The objective of this study was to determine whether a pre-training program influences the entire learning process and overall proficiency of colonoscopy during fellowship. Methods From March 2011 to February 2013, a total of 28 first-year gastrointestinal fellows were trained in colonoscopy at a single tertiary center. Before entering their fellowship training, all...

A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell death

Background Kainic acid (KA)-induced excitotoxicity promotes cytoplasmic calcium accumulation, oxidative stress, and apoptotic signaling, leading to hippocampal neuronal death. Mitochondria play a critical role in neuroinflammation and the oxidative stress response. Mitochondrial morphology is disrupted during KA-induced seizures; however, it is not clear whether mitochondrial...

Risk Factors for Acute Kidney Injury after Congenital Cardiac Surgery in Infants and Children: A Retrospective Observational Study

Acute kidney injury (AKI) after pediatric cardiac surgery is associated with high morbidity and mortality. Modifiable risk factors for postoperative AKI including perioperative anesthesia-related parameters were assessed. The authors conducted a single-center, retrospective cohort study of 220 patients (aged 10 days to 19 years) who underwent congenital cardiac surgery between...

Clinical Risk Scoring Models for Prediction of Acute Kidney Injury after Living Donor Liver Transplantation: A Retrospective Observational Study

Acute kidney injury (AKI) is a frequent complication of liver transplantation and is associated with increased mortality. We identified the incidence and modifiable risk factors for AKI after living-donor liver transplantation (LDLT) and constructed risk scoring models for AKI prediction. We retrospectively reviewed 538 cases of LDLT. Multivariate logistic regression analysis was...

How Can the Over-Use of Surveillance Colonoscopy After Polypectomy Be Modified?

Sung Pil Hong 0 Won Ho Kim 0 0 S. P. Hong W. H. Kim (&) Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine , 250 Seongsanno, Seodaemun-gu, Seoul

Obesity Is Independently Associated with Spinal Anesthesia Outcomes: A Prospective Observational Study

The influence of body-mass index (BMI) on spinal anesthesia is still controversial, with discrepant results reported in previous studies. To compare spinal anesthesia in obese and non-obese subjects, the anesthesia profiles in patients who underwent spinal anesthesia using intrathecal hyperbaric bupivacaine were compared. A total of 209 patients undergoing elective total knee...

Correlation of Serum-Soluble Triggering Receptor Expressed on Myeloid Cells-1 with Clinical Disease Activity in Inflammatory Bowel Disease

Erratum to: Dig Dis Sci DOI 10.1007/s10620-008-0514-5The following errors were published in this article.In the upper left corner of Fig. 2c, the expression P P = 0.001. Fig. 2Correlation analysis of disease activity in ulcerative colitis. Soluble TREM-1 level (a) was more highly correlated with disease activity (r = 0.849) than was ESR (b) (r = 0.619) or CRP (c) (r = 0.546). The...

NFATc4 and ATF3 Negatively Regulate Adiponectin Gene Expression in 3T3-L1 Adipocytes

Expression of adiponectin decreases with obesity and insulin resistance. At present, the mechanisms responsible for negatively regulating adiponectin expression in adipocytes are poorly understood. In this investigation, we analyzed the effects of 5′ serial deletion constructs on the murine adiponectin promoter. Here, we identified the repressor region located between −472 and...

Exposure to Chronic High Glucose Induces β-Cell Apoptosis Through Decreased Interaction of Glucokinase With Mitochondria: Downregulation of Glucokinase in Pancreatic β-Cells

Chronic hyperglycemia is toxic to pancreatic β-cells, impairing cellular functioning as observed in type 2 diabetes; however, the mechanism underlying β-cell dysfunction and the resulting apoptosis via glucose toxicity are not fully characterized. Here, using MIN6N8 cells, a mouse pancreatic β-cell line, we show that chronic exposure to high glucose increases cell death mediated...