Advanced search    

Search: authors:"Won-Ki Huh"

7 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Mitochondrial dysfunction reduces yeast replicative lifespan by elevating RAS-dependent ROS production by the ER-localized NADPH oxidase Yno1

) funded by the Ministry of Education, Science and Technology, Republic of Korea (www.nrf.re.kr) to Won-Ki Huh. The funders had no role in study design, data collection and analysis, decision to publish, or ... ) funded by the Ministry of Education, Science and Technology, Republic of Korea. 14 / 18 Author Contributions Conceptualization: Dae-Gwan Yi, Won-Ki Huh. Data curation: Dae-Gwan Yi, Sujin Hong. Formal

The β-1,3-glucanosyltransferase Gas1 regulates Sir2-mediated rDNA stability in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the stability of highly repetitive rDNA array is maintained through transcriptional silencing. Recently, a β-1,3-glucanosyltransferase Gas1 has been shown to play a significant role in the regulation of transcriptional silencing in S. cerevisiae. Here, we show that the gas1Δ mutation increases rDNA silencing in a Sir2-dependent manner. Remarkably, the...

Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae

Cheol Woong Ha 0 Won-Ki Huh 0 0 School of Biological Sciences, Research Center for Functional Cellulomics, Institute of Microbiology, Seoul National University , Seoul 151-747, Republic of Korea The

Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae

Cheol Woong Ha 0 Min-Kyung Sung 0 Won-Ki Huh 0 0 School of Biological Sciences and Research Center for Functional Cellulomics, Institute of Microbiology, Seoul National University , Seoul 151-747

Protein networks markedly improve prediction of subcellular localization in multiple eukaryotic species

The function of a protein is intimately tied to its subcellular localization. Although localizations have been measured for many yeast proteins through systematic GFP fusions, similar studies in other branches of life are still forthcoming. In the interim, various machine-learning methods have been proposed to predict localization using physical characteristics of a protein, such...

High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae

Chung 1 Young-Sung Lim 2 Won-Ki Huh 0 0 School of Biological Sciences and Research Center for Functional Cellulomics, Institute of Microbiology, Seoul National University , Seoul 151-747 , Republic of