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Reordering Transaction Execution to Boost High-Frequency Trading Applications

DEKE, Renmin University of China , Beijing , China 1 School of Information, Renmin University of China , Beijing , China 2 & Xiao Zhang 3 School of Data Science and Engineering, East China Normal

The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1

The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1 Xiao Zhang,1 Peng Li,1 Zhen Ding,1 Huili Wang,1 Junye Wang,1 ... OncoTargets and Therapy The putative tumor suppressor, mir-199a, regulated by snail, modulates clear cell renal cell carcinoma aggressiveness by repressing r OcK1 Xiao Zhang 1 2 Zhen Ding 1 2 Junye

Associations between RET tagSNPs and their haplotypes and susceptibility, clinical severity, and thyroid function in patients with differentiated thyroid cancer

Conceptualization: Ankui Yang. Data curation: Yongle Jiang, Xuan Su, Xiao Zhang, Weichao Chen, Zulu Ye, Tiancheng Deng, Wenze Deng. Formal analysis: Caiyun He, Jiangjun Ma, Xuan Su, Xiao Zhang, Tiancheng Deng

Protein deubiquitinase USP7 is required for osteogenic differentiation of human adipose-derived stem cells

Background Human adipose-derived stem cells (hASCs) are multipotent progenitor cells with self-renewal capabilities and multilineage differentiation potential, including osteogenesis. Although protein deubiquitinases have been linked to stem cell fate determination, whether protein deubiquitination contributes to lineage commitment during osteogenic differentiation of hASCs...

An example of host plant expansion of host-specialized Aphis gossypii Glover in the field

The host plant expansion of host-specialized Aphis gossypii (Glover) has been well studied in the laboratory; however, this phenomenon is poorly understood in the field. Here, we provide a series of laboratory and field experiments to assess the role of zucchini in the host plant expansion of cotton-specialized aphids. We observed that cotton-specialized aphids possessed the...

An I/O-Efficient Buffer Batch Replacement Policy for Update-Intensive Graph Databases

With the proliferation of graph-based applications, such as social network management and Web structure mining, update-intensive graph databases have become an important component of today’s data management platforms. Several techniques have been recently proposed to exploit locality on both data organization and computational model in graph databases. However, little...

Antioxidant Enzyme Responses Induced by Whiteflies in Tobacco Plants in Defense against Aphids: Catalase May Play a Dominant Role

Background Bemisia tabaci MEAM1 (Middle East-Asia Minor 1) feeding alters antioxidative enzyme activity in some plant species. Infestation of B. tabaci nymphs decreases Myzus persicae performance on systemic, but not local leaves of tobacco plants. However, it is unclear if B. tabaci nymphs induced antioxidant activities contributing to the aphid resistance. Methodology/Principal...

Cryptanalysis and Improvement of a Biometric-Based Multi-Server Authentication and Key Agreement Scheme

With the security requirements of networks, biometrics authenticated schemes which are applied in the multi-server environment come to be more crucial and widely deployed. In this paper, we propose a novel biometric-based multi-server authentication and key agreement scheme which is based on the cryptanalysis of Mishra et al.’s scheme. The informal and formal security analysis of...

Direct medical cost associated with diabetic retinopathy severity in type 2 diabetes in Singapore

Diabetic retinopathy (DR) is a leading cause of vision-loss globally among type 2 diabetes (T2DM) patients. Information on the economic burden of DR in Singapore is limited. We aim to identify the total annual direct medical costs of DR at different stages, and to examine factors influencing the costs. Four hundreds and seventy T2DM patients who attended the Diabetes Centre in a...

A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease

Background β-Amyloid peptide (Aβ) oligomers are initial factors used to induce Alzheimer’s disease (AD) development, and Aβ monomers have normal physiological function. The antibodies or vaccines against Aβ monomers have serious problems, such as side effects and low curative effects. Therefore, it is essential to specifically target Aβ oligomers rather than monomers for the...

Transcriptomes of three species of Tipuloidea (Diptera, Tipulomorpha) and implications for phylogeny of Tipulomorpha

Tipulomorpha has long been a problematic taxon in terms of familial composition, phylogenetic relationships among families and position relative to other ‘lower’ Diptera. Whole-transcriptome shotgun sequencing provides a powerful basis for phylogenetic studies. We performed de novo transcriptome sequencing to produce the first transcriptome datasets representing the families...

A novel visual facial anxiety scale for assessing preoperative anxiety

Background There is currently no widely accepted instrument for measuring preoperative anxiety. The objective of this study was to develop a simple visual facial anxiety scale (VFAS) for assessing acute preoperative anxiety. Methods The initial VFAS was comprised of 11 similarly styled stick-figure reflecting different types of facial expressions (Fig 1). After obtaining IRB...

A Fast Color Image Encryption Algorithm Using 4-Pixel Feistel Structure

Algorithms using 4-pixel Feistel structure and chaotic systems have been shown to resolve security problems caused by large data capacity and high correlation among pixels for color image encryption. In this paper, a fast color image encryption algorithm based on the modified 4-pixel Feistel structure and multiple chaotic maps is proposed to improve the efficiency of this type of...

Evaluation of treatments for sacroiliitis in spondyloarthropathy using the Spondyloarthritis Research Consortium Canada scoring system

Background In this study, the Spondyloarthritis Research Consortium Canada (SPARCC) scoring method was used to compare treatment methods in patients with axial spondyloarthritis (SpA), a form of sacroiliitis. MRI abnormalities in bone marrow edema (BME) were compared before and after treatment in order to compare the efficacy of anti-TNF-α and DMARD, alone or in combination, as...

Effects of Dental Implant-abutment Interfaces on the Reliability of Implant Systems

In this paper, by analyzing the effects of two different kinds of implant-abutment connection interfaces under the same working condition on the mechanical and fatigue performances of the implant system as well as on the surrounding bones, we intend to study such effects on the reliability of the implants and provide a theoretical basis for the design and clinical application of...

Decreased Expression of DREAM Promotes the Degeneration of Retinal Neurons

The intrinsic mechanisms that promote the degeneration of retinal ganglion cells (RGCs) following the activation of N-Methyl-D-aspartic acid-type glutamate receptors (NMDARs) are unclear. In this study, we have investigated the role of downstream regulatory element antagonist modulator (DREAM) in NMDA-mediated degeneration of the retina. NMDA, phosphate-buffered saline (PBS), and...

RET/PTC Rearrangements Are Associated with Elevated Postoperative TSH Levels and Multifocal Lesions in Papillary Thyroid Cancer without Concomitant Thyroid Benign Disease

RET/PTC rearrangements, resulting in aberrant activity of the RET protein tyrosine kinase receptor, occur exclusively in papillary thyroid cancer (PTC). In this study, we examined the association between RET/PTC rearrangements and thyroid hormone homeostasis, and explored whether concomitant diseases such as nodular goiter and Hashimoto's thyroiditis influenced this association...

Evaluation of water use structure and regulation to balance supply and demand in the Nansi Lake basin, China

In an established water supply system, the increasing demand for water resources caused by economic growth becomes a key issue for water resource management in China. From the water demand management perspective, this paper analyzed the mechanism of internal feedbacks among water resources, population, and economic mutual effects and established a system dynamics model to...

Co-administration of aspirin and allogeneic adipose-derived stromal cells attenuates bone loss in ovariectomized rats through the anti-inflammatory and chemotactic abilities of aspirin

Introduction Osteoporosis is a syndrome of excessive skeletal fragility characterized by the loss of mass and deterioration of microarchitecture in bone. Single use of aspirin or adipose-derived stromal cells (ASCs) has been recognized recently to be effective against osteoporosis. The goal of the study was to evaluate the osteogenic effects of the co-administration of aspirin...