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The pathophysiological role of mitochondrial oxidative stress in lung diseases

Mitochondria are critically involved in reactive oxygen species (ROS)-dependent lung diseases, such as lung fibrosis, asbestos, chronic airway diseases and lung cancer. Mitochondrial DNA (mtDNA) encodes mitochondrial proteins and is more sensitive to oxidants than nuclear DNA. Damage to mtDNA causes mitochondrial dysfunction, including electron transport chain impairment and...

Empirical Research on Industrial Design Contribution Rate under Statistical Frame

. Dongliang Chen , The value of industrial design, Oriental Enterprise Culture , 2 ( 2011 ) 2. Xiaojing Liu, Research on value evaluation of industrial design ,An empirical research report based on the

Nutrients resorption and stoichiometry characteristics of different-aged plantations of Larix kaempferi in the Qinling Mountains, central China

Bioresources of Saline Soils (No. YT2014-02), Jiangsu Provincial Environmental Protection Research Project (No. 2016044). Author Contributions Conceptualization: Xiaojing Liu. Data curation: Wei Wang

Gene Expression Profile in the Long-Living Lotus: Insights into the Heat Stress Response Mechanism

Lotus (Nelumbo Adans) is an aquatic perennial plant that flourished during the middle Albian stage. In this study, we characterized the digital gene expression signatures for China Antique lotus under conditions of heat shock stress. Using RNA-seq technology, we sequenced four libraries, specifically, two biological replicates for control plant samples and two for heat stress...

Highly Efficient Catalysis of Azo Dyes Using Recyclable Silver Nanoparticles Immobilized on Tannic Acid-Grafted Eggshell Membrane

In this study, a facile one-step synthesis of a novel nanocomposite catalytic film was developed based on silver nanoparticles (AgNPs) immobilized in tannic acid-modified eggshell membrane (Tan-ESM). Tannic acid, as a typical plant polyphenol from oak wood, was first grafted onto ESM fibers to serve as both the reductant and the stabilizer during the synthesis of AgNPs. The...

Rab1A mediates proinsulin to insulin conversion in β-cells by maintaining Golgi stability through interactions with golgin-84

National Natural Science Foundation of China (Grant Nos. 31130034 and 31470808), and Strategic Priority Research Program of the Chinese Academy of Sciences (XDA12000000). Xiaojing Liu, Zhenguo Wang, Ying

Roles of microRNA-34a targeting SIRT1 in mesenchymal stem cells

Introduction Mesenchymal stem cell (MSC)-based therapies have had positive outcomes both in animal models of cardiovascular diseases and in clinical patients. However, the number and function of MSCs decline during hypoxia and serum deprivation (H/SD), reducing their ability to contribute to endogenous injury repair. MicroRNA-34a (miR-34a) is originally identified as a TP53...

Hormonal and environmental regulation of seed germination in salt cress (Thellungiella halophila)

Thellungiella halophila (salt cress) is a salt tolerant species with high genetic and morphological similarity to model plant Arabidopsis thaliana. The role of growth regulators in imposing seed dormancy and a release from it while responding to environmental signals has been examined. Seeds of salt cress possess a deep dormancy at maturity which decreased during after-ripening...

One-Step Solvothermal Method to Prepare Ag/Cu2O Composite With Enhanced Photocatalytic Properties

Ag/Cu2O microstructures with diverse morphologies have been successfully synthesized with different initial reagents of silver nitrate (AgNO3) by a facile one-step solvothermal method. Their structural and morphological characteristics were carefully investigated by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM...

Identification and Characterization of MicroRNAs in Ginkgo biloba var. epiphylla Mak

Ginkgo biloba, a dioecious plant known as a living fossil, is an ancient gymnosperm that stands distinct from other gymnosperms and angiosperms. Ginkgo biloba var. epiphylla (G. biloba var. epiphylla), with ovules borne on the leaf blade, is an unusual germplasm derived from G. biloba. MicroRNAs (miRNAs) are post-transcriptional gene regulators that play critical roles in diverse...

Estimating Relative Changes of Metabolic Fluxes

Fluxes are the central trait of metabolism and Kinetic Flux Profiling (KFP) is an effective method of measuring them. To generalize its applicability, we present an extension of the method that estimates the relative changes of fluxes using only relative quantitation of 13C-labeled metabolites. Such features are directly tailored to the more common experiment that performs only...

Existence of positive solutions of advanced differential equations

In this paper, we study the advanced differential equations [ r ( t ) | x ′ ( t ) | α − 1 x ′ ( t ) ] ′ + ∑ i = 1 n p i ( t ) | x ( t + τ i ( t ) ) | α − 1 x ( t + τ i ( t ) ) = 0 and [ r ( t ) ( y ( t ) − P ( t ) y ( t − τ ) ) ′ ] ′ + ∑ i = 1 n p i ( t ) f ( y ( t + σ ) ) = 0 . By using the generalized Riccati transformation and the Schauder-Tyichonoff theorem, we establish the...

Liver Fat Content Is Associated with Elevated Serum Uric Acid in the Chinese Middle-Aged and Elderly Populations: Shanghai Changfeng Study

Background and Aims Although many studies have indicated a relationship between nonalcoholic fatty liver disease (NAFLD) and hyperuricemia, a few studies specifically examining the effects of the severity of liver fat content (LFC) on serum uric acid (SUA) and the presence of hyperuricemia because of the limitation of the examination methods for NAFLD. In this study, we...

Existence of positive solutions of advanced differential equations

In this paper, we study the advanced differential equations [ r ( t ) | x ′ ( t ) | α − 1 x ′ ( t ) ] ′ + ∑ i = 1 n p i ( t ) | x ( t + τ i ( t ) ) | α − 1 x ( t + τ i ( t ) ) = 0 and [ r ( t ) ( y ( t ) − P ( t ) y ( t − τ ) ) ′ ] ′ + ∑ i = 1 n p i ( t ) f ( y ( t + σ ) ) = 0 . By using the generalized Riccati transformation and the Schauder-Tyichonoff theorem, we establish the...

Variation in soil respiration under the tree canopy in a temperate mixed forest, central China, under different soil water conditions

The forest canopy cover can directly and indirectly affect soil conditions and hence soil carbon emission through soil respiration. Little is known, however, on the effects of canopy cover on soil respiration under the canopy of different tree species and soil water conditions. We have examined the variation in soil respiration at different soil water conditions (dry <10 %, wet...

Quality of reporting on randomized controlled trials on recurrent spontaneous abortion in China

Background Despite increasing numbers of RCTs done in China, detailed information on the quality of Chinese RCTs is still missing. The aim of this study was to assess the reporting quality of RSA RCTs and to identify significant predictors of reporting quality. Methods A literature review was conducted with the aim of identifying published RCTs on RSA conducted in China. In order...

Expression of transient receptor potential channel 6 in cervical cancer

Expression of transient receptor potential channel 6 in cervical cancer Qi Wan,1 Ai Zheng,1 Xiaojing Liu,2 Yali Chen,1 Ling Han11Department of Obstetric and Gynecology, West China Second University ... Diseases, Regenerative Medicine Research Center, West China Hospital, Sichuan University , Chengdu , China 1 Xiaojing Liu Laboratory of Cardiovascular Diseases, Regenerative Medicine Research Center, West

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

Aerobic glycolysis or the Warburg Effect (WE) is characterized by the increased metabolism of glucose to lactate. It remains unknown what quantitative changes to the activity of metabolism are necessary and sufficient for this phenotype. We developed a computational model of glycolysis and an integrated analysis using metabolic control analysis (MCA), metabolomics data, and...

Hypoxia stimulates the expression of macrophage migration inhibitory factor in human vascular smooth muscle cells via HIF-1α dependent pathway

(Xiaojing Liu), No. 30871118, 30971325 (Fengming Luo), the projects of Science and Technology Bureau of Sichuan Province No.2008FZ0156 (Hua Fu), No. 2009FZ0097 (Li Yang), the project of Science and Technology

An organ-specific role for ethylene in rose petal expansion during dehydration and rehydration

Dehydration is a major factor resulting in huge loss from cut flowers during transportation. In the present study, dehydration inhibited petal cell expansion and resulted in irregular flowers in cut roses, mimicking ethylene-treated flowers. Among the five floral organs, dehydration substantially elevated ethylene production in the sepals, whilst rehydration caused rapid and...