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Feedback control effect on the Lotka-Volterra prey-predator system with discrete delays

In this paper, we study a Lotka-Volterra prey-predator system with feedback control. We establish sufficient conditions under which a unique positive equilibrium is globally stable. Further, we show that a suitable feedback control on predator species can make prey species that is on the brink of extinction become globally stable, but under the conditions of small feedback...

Feedback control effect on the Lotka-Volterra prey-predator system with discrete delays

In this paper, we study a Lotka-Volterra prey-predator system with feedback control. We establish sufficient conditions under which a unique positive equilibrium is globally stable. Further, we show that a suitable feedback control on predator species can make prey species that is on the brink of extinction become globally stable, but under the conditions of small feedback...

Feedback control effect on the Lotka-Volterra prey-predator system with discrete delays

In this paper, we study a Lotka-Volterra prey-predator system with feedback control. We establish sufficient conditions under which a unique positive equilibrium is globally stable. Further, we show that a suitable feedback control on predator species can make prey species that is on the brink of extinction become globally stable, but under the conditions of small feedback...

Distinct virulent network between healthcare- and community-associated Staphylococcus aureus based on proteomic analysis

Background Staphylococcus aureus (S. aureus or SA) is a leading cause of healthcare-associated (HA-) and community-associated (CA) infection. HA-SA isolates usually cause nosocomial pneumonia, bloodstream infections, catheter-related urinary tract infections, etc. On the other hand, CA-SA isolates usually cause highly fatal diseases, such as SSTIs as well as post influenza...

Working memory test battery for young adults: Computerized working memory assessment

This study developed a battery of computerized working memory (WM) tests and a scoring system suitable for young adult users. The tests comprised five classic tasks derived from Baddeley’s model of WM, reflecting each of the five WM functions. We recruited 115 undergraduate and graduate students from various academic fields and constructed a preliminary WM scoring norm for young...

Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis

Background Chemotherapy-induced premature ovarian failure (POF) is a severe complication affecting tumor patients at a childbearing age. Mesenchymal stem cells (MSCs) can partially restore the ovarian structure and function damaged by chemotherapy. miR-21 is a microRNA that can regulate cell apoptosis. This study discusses the repair effect and mechanism of MSCs overexpressing...

Almost periodic solution of a discrete Nicholson’s blowflies model with delay and feedback control

In this paper, we propose a discrete Nicholson’s blowflies model with feedback control. Sufficient conditions are obtained for the permanence. By means of an almost periodic functional hull theory, we show that the almost periodic system has a uniqueness of globally attractive almost periodic solution. Moreover, a suitable example and its numerical simulation are given to...

Costs of chronic obstructive pulmonary disease in urban areas of China: a cross-sectional study in four cities

Costs of chronic obstructive pulmonary disease in urban areas of China: a cross-sectional study in four cities Xiaoying Chen,1,2 Na Wang,1,2 Yue Chen,3 Tian Xiao,1,2 Chaowei Fu,1,2 Biao Xu1,2

The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling

Pharmacology and DMPK, MedImmune, Cambridge CB21 6GH, UK. Conflict of Interests All authors are current or former employees of Pfizer Inc. Authors’ Contribution Xiaoying Chen and Abhinav Tiwari contributed to

SSTR2 promoter hypermethylation is associated with the risk and progression of laryngeal squamous cell carcinoma in males

1 Department of Otorhinolaryngology (Head and Neck Surgery), Lihuili Hospital of Ningbo University , Ningbo, Zhejiang 315040 , China 2 Zhisen Shen and Xiaoying Chen are co-first authors of this work

Nuclear PKM2 contributes to gefitinib resistance via upregulation of STAT3 activation in colorectal cancer

information AffiliationsDepartment of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, ChinaQiong Li, Xiaoying Chen, Lei He, Tianming Li, Xiaoping Xu ... for Daoxiang Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Xiaoying Chen in:Nature Research journals • PubMed • Google ScholarSearch for Lei He in:Nature Research journals

Note on the Persistence of a Nonautonomous Lotka-Volterra Competitive System with Infinite Delay and Feedback Controls

We study a nonautonomous Lotka-Volterra competitive system with infinite delay and feedback controls. We establish a series of criteria under which a part of -species of the systems is driven to extinction while the remaining part of the species is persistent. Particularly, as a special case, a series of new sufficient conditions on the persistence for all species of system are...

Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease

Background Chronic inflammation has been widely considered to be the major risk factor of coronary heart disease (CHD). The goal of our study was to explore the possible association with CHD for inflammation-related single nucleotide polymorphisms (SNPs) involved in cytosine-phosphate-guanine (CpG) dinucleotides. A total of 784 CHD patients and 739 non-CHD controls were recruited...

Up-regulation of long non-coding RNA PANDAR is associated with poor prognosis and promotes tumorigenesis in bladder cancer

Background Long non-coding RNAs (lncRNAs) have emerged as biomarkers and important regulators of tumor development and progression. PANDAR (promoter of CDKN1A antisense DNA damage activated RNA) is a novel long non-coding RNA that acts as a potential biomarker and involves in development of multiple cancers. However, the clinical significance and molecular mechanism of PANDAR in...

Coupled electrophysiological recording and single cell transcriptome analyses revealed molecular mechanisms underlying neuronal maturation

-differential interference contrast; NSC/ NPC, neural stem/progenitor cell; WGCNA, weighted gene coexpression network analyses. COMPLIANCE WITH ETHICS GUIDELINES Xiaoying Chen, Kunshan Zhang, Liqiang Zhou

Facilitative and Inhibitory Effect of Litter on Seedling Emergence and Early Growth of Six Herbaceous Species in an Early Successional Old Field Ecosystem

In the current study, a field experiment was conducted to examine effects of litter on seedling emergence and early growth of four dominant weed species from the early successional stages of old field ecosystem and two perennial grassland species in late successional stages. Our results showed that increased litter cover decreased soil temperature and temperature variability over...

Facile synthesis of folate-conjugated magnetic/fluorescent bifunctional microspheres

In this paper, we investigated the functional imaging properties of magnetic microspheres composed of magnetic core and CdTe quantum dots in the silica shell functionalized with folic acid (FA). The preparation procedure included the preparation of chitosan-coated Fe3O4 nanoparticles (CS-coated Fe3O4 NPs) prepared by a one-pot solvothermal method, the reaction between carboxylic...

Plant-Generated Artificial Small RNAs Mediated Aphid Resistance

Background RNA silencing is an important mechanism for regulation of endogenous gene expression and defense against genomic intruders in plants. This natural defense system was adopted to generate virus-resistant plants even before the mechanism of RNA silencing was unveiled. With the clarification of that mechanism, transgenic antiviral plants were developed that expressed...

Consecutive Spawnings of Chinese Amphioxus, Branchiostoma belcheri, in Captivity

Cephalochordate amphioxus is a promising model animal for studying the evolutionary and developmental mechanisms of vertebrates because its unique phylogenetic position, simple body plan and sequenced genome. However, one major drawback for using amphioxus as a model organism is the restricted supply of living embryos since they are available only during spawning season that...

Association of vitamin D receptor gene polymorphisms with metabolic syndrome: a case–control design of population-based cross-sectional study in North China

Background Metabolic syndrome (MS) increases a risk of developing cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). The Vitamin D Receptor gene (VDR) may be important for developing MS. The aim of this study is to investigate the correlation between the VDR gene polymorphisms and MS in North China. Methods A case–control study included 391 participants with MS...