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Finslerian dipolar modulation of the CMB power spectra at scales \(2<l<600\)

A common explanation for the CMB power asymmetry is to introduce a dipolar modulation at the stage of inflation, where the primordial power spectrum is spatially varying. If the universe in the stage of inflation is Finslerian, and if the Finsler spacetime is non-reversible under parity flip, \(x\rightarrow -x\), then a three dimensional spectrum which is a function of wave vector ...

Magnesium hydroxide whisker modified via in situ copolymerization of n-butyl acrylate and maleic anhydride

Magnesium hydroxide (MH) whiskers were modified via in situ polymerization of n-butyl acrylate and maleic anhydride. Sodium dodecyl sulfonate was used as emulsifier. The modifying effect was evaluated by using contact angle and activation index. The thermal stability, functional groups, structure, morphology, phase composition and surface element valence of MH whiskers were ...

The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly

The PICALM rs541458 T allele has been recognized as a risk factor for late-onset Alzheimer’s disease, and age might modulate the effects that genetic factors have on cognitive functions and brain. Thus, the current study intended to examine whether the effects of rs541458 on cognitive functions, brain structure, and function were modulated by age in non-demented Chinese elderly. We ...

An AGC system with a PGA for GPS/BDS dual system compatible receiver

GPS/BDS dual system compatible receiver chip based on the proposed AGC system in this work has been taped out successfully, and achieves a tracking sensitivity of -137 dBm. Xin Li received the B.S

Long non-coding RNAs: potential new biomarkers for predicting tumor invasion and metastasis

Long non-coding RNAs (lncRNAs) play important roles in malignant neoplasia. Indeed, many hallmarks of cancer define that the malignant phenotype of tumor cells are controlled by lncRNAs. Despite a growing number of studies highlighting their importance in cancer, there has been no systematic review of metastasis-associated lncRNAs in various cancer types. Accordingly, we focus on ...

The prognostic factors for patients with hematological malignancies admitted to the intensive care unit

for Xin Li and the Innovative Research Funds For the Central South University, No. 2016zzts151 for Qian Cheng and 2016zzts567 for Yishu Tang. This review has been copy edited for proper English language

Primordial power spectrum of tensor perturbations in Finsler spacetime

We first investigate the gravitational wave in the flat Finsler spacetime. In the Finslerian universe, we derive the perturbed gravitational field equation with tensor perturbations. The Finslerian background spacetime breaks rotational symmetry and induces parity violation. Then we obtain the modified primordial power spectrum of the tensor perturbations. The parity violation ...

Predicting existing targets for new drugs base on strategies for missing interactions

Background There has been paid more and more attention to supervised classification models in the area of predicting drug-target interactions (DTIs). However, in terms of classification, unavoidable missing DTIs in data would cause three issues which have not yet been addressed appropriately by former approaches. Directly labeled as negatives (non-DTIs), missing DTIs increase the ...

A proteomic analysis of acute leukemia cells treated with 9-hydroxyoctadecadienoic acid

Background 9s-hydroxy-octadecadienoic acid (9S-HOD), one of the natural products of linoleic acid oxygenation by 15-lipoxygenase (15-LOX), has been found to have anti-tumor properties in vitro and in vivo. The present study therefore investigated whether 9S-HOD affects acute leukemia HL-60 cells. Methods The cytotoxicity of 9S-HOD in HL-60 with or without the presence of fetal ...

The association between oxidized low-density lipoprotein antibodies and hematological diseases

below made their substantial contributions to this manuscript. Hao Li and Da-qing Li design of this study, data analysis, and drafted the manuscript. Xiang-xin Li and Lu-qun Wang carried out the assay

Leakage diffusion of underwater crude oil in wind fields

Leakage of underwater crude oil pipes causes severe pollution to soil and water, and results in great economic loss. To predict the diffusion area of spilled oil before it reaches the water’s surface and to reduce the time required for emergency response, numerical simulations were conducted on underwater spilled oil diffusion of bare crude oil pipes using FLUENT software. The ...

The identification of human aldo-keto reductase AKR7A2 as a novel cytoglobin-binding partner

Cytoglobin (CYGB), a member of the globin family, is thought to protect cells from reactive oxygen and nitrogen species and deal with hypoxic conditions and oxidative stress. However, its molecular mechanisms of action are not clearly understood. Through immunoprecipitation combined with a two-dimensional electrophoresis–mass spectrometry assay, we identified a CYGB interactor: ...

LincSNP 2.0: an updated database for linking disease-associated SNPs to human long non-coding RNAs and their TFBSs

We describe LincSNP 2.0 (http://bioinfo.hrbmu.edu.cn/LincSNP), an updated database that is used specifically to store and annotate disease-associated single nucleotide polymorphisms (SNPs) in human long non-coding RNAs (lncRNAs) and their transcription factor binding sites (TFBSs). In LincSNP 2.0, we have updated the database with more data and several new features, including (i) ...

The existence of solutions of q-difference-differential equations

By using the Nevanlinna theory of value distribution, we investigate the existence of solutions of some types of non-linear q-difference differential equations. In particular, we generalize the Rellich–Wittich-type theorem and Malmquist-type theorem about differential equations to the case of q-difference differential equations (system).

The improvement of centralized intelligent control architecture and data collection algorithm

The commonly used structure of centralized temperature control systems is the bi-layer structure with upper computer directly controlling thermostats. But this kind of structure has obvious drawbacks, such as high cost, inability to scale up, low degree of intelligence, etc.. This paper presents a design scheme of an intelligent three-tier structure, namely thermostats, intelligent ...

Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression

Breast cancer causes the No.1 women cancer prevalence and the No.2 women cancer mortality worldwide. Nuclear receptor/transcriptional factor signaling is aberrant and plays important roles in breast cancer pathogenesis and evolution, such as estrogen receptor α (ERα/ESR1), tumor protein p53 (p53/TP53) and Nuclear factor kappa B (NFκB). About 60–70 % of breast tumors are ERα ...

SpliceJumper: a classification-based approach for calling splicing junctions from RNA-seq data

Background Next-generation RNA sequencing technologies have been widely applied in transcriptome profiling. This facilitates further studies of gene structure and expression on the genome wide scale. It is an important step to align reads to the reference genome and call out splicing junctions for the following analysis, such as the analysis of alternative splicing and isoform ...

Neck circumference and future cardiovascular events in a high-risk population—A prospective cohort study

Background The distribution of adipose tissue has been evaluated in relation to cardiovascular risk factors and biochemical components of the metabolic syndrome. Neck circumference (NC) has been shown to have a strong relationship with cardiovascular disease (CVD) and may be a novel indicator of CVD. The aim of this study was to compare the incidence of CVD events in cohorts with ...

CD317 Promotes the survival of cancer cells through apoptosis-inducing factor

Background Low nutrient environment is a major obstacle to solid tumor growth. However, many tumors have developed adaptive mechanisms to circumvent the requirement for exogenous growth factors. Methods Here we used siRNA interference or plasmid transfection techniques to knockdown or enhance CD317 expression respectively, in mammalian cancer cells, and subjected these ...

Multivariate Gene-Based Association Test on Family Data in MGAS

In analyses of unrelated individuals, the program multivariate gene-based association test by extended Simes (MGAS), which facilitates multivariate gene-based association testing, was shown to have correct Type I error rate and superior statistical power compared to other multivariate gene-based approaches. Here we show, through simulation, that MGAS can also be applied to data ...