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Test the mergers of the primordial black holes by high frequency gravitational-wave detector

The black hole could have a primordial origin if its mass is less than \(1M_\odot \). The mergers of these black hole binaries generate stochastic gravitational-wave background (SGWB). We investigate the SGWB in high frequency band \(10^{8}\)–\(10^{10}\,\mathrm {Hz}\). It can be detected by high frequency gravitational-wave detector. Energy density spectrum and amplitude of the ...

Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations

Previous studies have indicated that tumor mitochondrial DNA (mtDNA) mutations are primarily shaped by relaxed negative selection, which is contradictory to the critical roles of mtDNA mutations in tumorigenesis. Therefore, we hypothesized that site-specific selection may influence tumor mtDNA mutations. To test our hypothesis, we developed the largest collection of tumor mtDNA ...

Finslerian dipolar modulation of the CMB power spectra at scales \(2<l<600\)

A common explanation for the CMB power asymmetry is to introduce a dipolar modulation at the stage of inflation, where the primordial power spectrum is spatially varying. If the universe in the stage of inflation is Finslerian, and if the Finsler spacetime is non-reversible under parity flip, \(x\rightarrow -x\), then a three dimensional spectrum which is a function of wave vector ...

CO hydrogenation combined with water-gas-shift reaction for synthetic natural gas production: a thermodynamic and experimental study

The hydrogenation of CO to synthetic natural gas (SNG) needs a high molar ratio of H2/CO (usually large than 3.0 in industry), which consumes a large abundant of hydrogen. The reverse dry reforming reaction (RDR, 2H2 + 2CO ↔ CH4 + CO2), combining CO methanation with water-gas-shift reaction, can significantly decrease the H2/CO molar ratio to 1 for SNG production. A detailed ...

The purification of reduced β2-glycoprotein I showed its native activity in vitro

New evidence has shown that reduced β2-glycoprotein I (β2GPI) has anti-oxidative stress and anti-inflammatory activity. However, the details are still poorly understood. This study aims to prepare stable reduced β2GPI with its native bioactivity in vitro. Human β2GPI was purified from plasma first with perchloric acid precipitation and then purified with a series of chromatography ...

Quantitative thyroglobulin response to radioactive iodine treatment in predicting radioactive iodine-refractory thyroid cancer with pulmonary metastasis

: Chen Wang, Yansong Lin. Data curation: Chen Wang, Xin Zhang. Formal analysis: Chen Wang, Xin Zhang. Funding acquisition: Yansong Lin. Methodology: Xin Zhang, Hui Li, Xin Li. Project administration ... : Hui Li, Xin Li. Resources: Chen Wang, Xin Li. Software: Hui Li, Xin Li. Supervision: Xin Li. Validation: Xin Zhang, Hui Li. Visualization: Chen Wang, Hui Li. Writing ± original draft: Chen Wang

A brain-inspired SLAM system based on ORB features

This paper describes a brain-inspired simultaneous localization and mapping (SLAM) system using oriented features from accelerated segment test and rotated binary robust independent elementary (ORB) features of RGB (red, green, blue) sensor for a mobile robot. The core SLAM system, dubbed RatSLAM, can construct a cognitive map using information of raw odometry and visual scenes in ...

Shrinkage function and its applications in matrix approximation

The shrinkage function is widely used in matrix low-rank approximation, compressive sensing, and statistical estimation. In this article, an elementary derivation of the shrinkage function is given. In addition, applications of the shrinkage function are demonstrated in solving several well-known problems, together with a new result in matrix approximation.

Reduced Port Laparoscopic Distal Gastrectomy with D2 Lymphadenectomy

Background Reduced port laparoscopic surgery (RPLS), as a more minimally invasive treatment alternative to conventional laparoscopic surgery (CLS), has been increasing in recent years. 1 With the accumulation of surgical experience and improvements in surgical techniques, the indication of RPLS has been gradually extended from benign diseases to malignant tumors, including gastric ...

Isoalantolactone induces intrinsic apoptosis through p53 signaling pathway in human lung squamous carcinoma cells

: Guangxin Zhang, Yifan Zhang. Writing ± original draft: Xingyi Zhang. Writing ± review & editing: Mei Sun, Xin Li, Ti Tong, Xingyi Zhang. 11 / 12 genes encoding Bax and p21(CIP1/Waf1). Oncogene. 2002; 21

Effects of Insulin Plus Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in Treating Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Institute of Endocrinology at Tianjin Medical University. Xin Li is a doctor at the Key Laboratory of Hormones and Development (Ministry of Health) in the Metabolic Diseases Hospital & Tianjin Institute of

Suppression of cucumber stachyose synthase gene (CsSTS) inhibits phloem loading and reduces low temperature stress tolerance

Stachyose is the main transporting sugar in phloem of Raffinose family oligosaccharides-transporting species. Stachyose synthase (STS) is a key enzyme for stachyose biosynthesis, but the gene encoding STS is poorly characterized in cucumber (Cucumis sativus L.), which is a model plant for studying stachyose metabolism and phloem function. In this research, stachyose synthase gene ...

A plasma mir-125a-5p as a novel biomarker for Kawasaki disease and induces apoptosis in HUVECs

Background Kawasaki disease (KD) is a childhood systemic vasculitis that exhibits a specific preference for the coronary arteries. The aetiology remains unknown and there are no especially diagnostic tests. microRNAs (miRNAs) are 18 to 23 nucleotides non-coding RNAs that are negative regulator of gene expression and play a crucial role in the regulatory network of the genome. ...

Comprehensive evaluation of ten deformable image registration algorithms for contour propagation between CT and cone-beam CT images in adaptive head & neck radiotherapy

Deformable image registration (DIR) is a critical technic in adaptive radiotherapy (ART) for propagating contours between planning computerized tomography (CT) images and treatment CT/cone-beam CT (CBCT) images to account for organ deformation for treatment re-planning. To validate the ability and accuracy of DIR algorithms in organ at risk (OAR) contour mapping, ten ...

Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells

Pancreatic β cell dysfunction and reduction due to glucose toxicity play a crucial role in the development of type 2 diabetes mellitus (T2DM). Irisin, a novel exercise-induced myokine, reduces obesity, improves insulin resistance and lowers blood glucose by promoting the browning of white adipose tissue, thereby enhancing thermogenesis and increasing energy expenditure. Recent ...

Human paleodiet and animal utilization strategies during the Bronze Age in northwest Yunnan Province, southwest China

Reconstructing ancient diets and the use of animals and plants augment our understanding of how humans adapted to different environments. Yunnan Province in southwest China is ecologically and environmentally diverse. During the Neolithic and Bronze Age periods, this region was occupied by a variety of local culture groups with diverse subsistence systems and material culture. In ...

A Novel Self-Assembling DNA Nano Chip for Rapid Detection of Human Papillomavirus Genes

Rapid detection of tumor-associated DNA such as Human Papillomavirus (HPV) has important clinical value for the early screening of tumors. By attaching oligonucleotides or cDNA onto the chip surface, DNA chip technology provides a rapid method to analyze gene expression. However, challenges remain regarding increasing probe density and improving detection time. To address these ...

The temporal behavior and consistency of bipolar atrial electrograms in human persistent atrial fibrillation

. Bell has investigated signal processing techniques to understand the underlying dynamics of atrial fibrillation perpetuation. Dr. Xin Li obtained B.Sc. in E l e c t r i c a l I n f o r m a t i o n

An AGC system with a PGA for GPS/BDS dual system compatible receiver

GPS/BDS dual system compatible receiver chip based on the proposed AGC system in this work has been taped out successfully, and achieves a tracking sensitivity of -137 dBm. Xin Li received the B.S