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65 papers found.
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MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB

Conceptualization: Xufeng Chen, Xu Zhang. Data curation: Shaoxi Niu. Formal analysis: Shaoxi Niu. Funding acquisition: Xin Ma. Methodology: Yu Zhang. Project administration: Xu Zhang. Resources: Xu Zhang

Bone marrow CD34+ cell subset under induction of moderate stiffness of extracellular matrix after myocardial infarction facilitated endothelial lineage commitment in vitro

Background The stiffness of the myocardial extracellular matrix (ECM) and the transplanted cell type are vitally important in promoting angiogenesis. However, the combined effect of the two factors remains uncertain. The purpose of this study is to investigate in vitro the combined effect of myocardial ECM stiffness postinfarction with a bone marrow-derived cell subset expressing...

DNABP: Identification of DNA-Binding Proteins Based on Feature Selection Using a Random Forest and Predicting Binding Residues

DNA-binding proteins are fundamentally important in cellular processes. Several computational-based methods have been developed to improve the prediction of DNA-binding proteins in previous years. However, insufficient work has been done on the prediction of DNA-binding proteins from protein sequence information. In this paper, a novel predictor, DNABP (DNA-binding proteins), was...

Temperature evolution and grain defect formation during single crystal solidification of a blade cluster

In order to investigate the asymmetry of thermal conditions during directional solidification, the temperature evolution and correspondingly developed undercooling in a simplified single crystal blade cluster were numerically simulated. Simulation results demonstrate that the temperature distribution at the blade platforms is obviously asymmetrical. On the outside of the blade...

Seasonal variations in carbon, nitrogen and phosphorus concentrations and C:N:P stoichiometry in different organs of a Larix principis-rupprechtii Mayr. plantation in the Qinling Mountains, China

, Xing Gao, Xingxing Li, Pei Zhang, Xin Ma. Methodology: Hailiang Li, M. James C. Crabbe, Fuli Xu, Ruilong Niu, Xing Gao, Haikui Chen. Project administration: Fuli Xu, Weiling Wang. Resources: Fuli Xu

Use of the MATRICS consensus cognitive battery (MCCB) to evaluate cognitive deficits in bipolar disorder: A systematic review and meta-analysis

Background The Measurement and Treatment Research to Improve Cognition Schizophrenia Consensus Cognitive Battery (MCCB) has also been proposed for use in clinical trials to assess cognitive deficits in patients with bipolar disorder (BD). The aim of this study was to evaluate cognitive function assessed by the MCCB in BD. Methods A literature search of the PubMed, Embase...

Qualities of Life of Patients with Psychotic Disorders and Their Family Caregivers: Comparison between Hospitalised and Community-Based Treatment in Beijing, China

Background Community healthcare in mainland China is still at an early stage. The qualities of life (QOLs) of patients with psychotic disorders undergoing rehabilitation in hospitals or in the community, as well as those of their caregivers, may differ from each other. Objectives The study was performed to evaluate the QOL of patients with psychotic disorders and assess the...

Influence of tumor size on oncological outcomes of pathological T3aN0M0 renal cell carcinoma treated by radical nephrectomy

Objective To evaluate the prognostic significance of tumor size in pathological T3aN0M0 renal cell carcinoma (RCC) treated by radical nephrectomy. Materials and methods Patients who underwent radical nephrectomy for sporadic RCC with pathological T3aN0M0 RCC at our institution between January 2006 and June 2015 were identified. The entire cohort was divided into two groups...

Prolactin related symptoms during risperidone maintenance treatment: results from a prospective, multicenter study of schizophrenia

Background This study aimed to investigate prolactin related symptoms (PRS) in individuals with schizophrenia during risperidone maintenance treatment for one year, as well as to identify the risk factors for PRS. Methods In a multicenter, randomized, controlled, longitudinal study, clinically stabilized schizophrenia patients (N = 374) were randomized to a no-dose-reduction...

Design of an ultrasonic motor with multi-vibrators

This paper presents and verifies a new idea for constructing an ultrasonic motor (USM). The stator contains several vibrators fabricated by bonding piezoelectric ceramics (PZTs) to a metal base. When two alternating current (AC) voltages with a 90° phase difference are applied to the PZTs, longitudinal and bending modes are excited in the vibrator. The bending vibrations of the...

A comparative analysis of the relationship between learning styles and mathematics performance

Background As an effort to account for disparities in mathematics performance between American and East Asian middle school students, the present research aims to compare the relationship between learning styles (competitive and cooperative) and mathematics performance among middle school students between the USA and the three top-performing East Asian countries (Hong Kong, Japan...

Upregulation of Far Upstream Element-Binding Protein 1 (FUBP1) Promotes Tumor Proliferation and Tumorigenesis of Clear Cell Renal Cell Carcinoma

Objective The far upstream element (FUSE)-binding protein 1 (FUBP1) is a transactivator of human c-myc proto-oncogene transcription, with important roles in carcinogenesis. However, the expression pattern and potential biological function of FUBP1 in clear cell renal cell carcinoma (ccRCC) is yet to be established. Methods FUBP1 expression was detected in ccRCC tissues and cell...

Bilateral Synchronous Sporadic Renal Cell Carcinoma: Retroperitoneoscopic Strategies and Intermediate Outcomes of 60 Patients

Objective To evaluate the presentation, management, pathology, and functional and oncological outcomes of patients undergoing retroperitoneoscopic treatment of bilateral synchronous sporadic RCC at our institution. Methods We retrospectively evaluated the records of 60 patients with bilateral synchronous sporadic RCC who underwent retroperitoneoscopic treatment at the General...

Effects of receptor for advanced glycation endproducts on microvessel formation in endometrial cancer

Background The receptor for advanced glycation endproducts (RAGE) and microvascular status both play a critical role in cancer progression. However, the crosstalk between RAGE and microvascular formation in endometrial cancer remains largely unknown. Methods RAGE expression and microvessel density were examined in 20 cases of normal endometrial tissue, 37 cases of well...

RhoB Acts as a Tumor Suppressor That Inhibits Malignancy of Clear Cell Renal Cell Carcinoma

This study aims to investigate the biological role of RhoB in clear cell renal cell carcinoma (ccRCC). The expression of RhoB was examined in specimens of patients and cell lines by Western blot and Immunohistochemistry. The correlation between RhoB expression and clinicopathologic variables was also analyzed. The effects of RhoB on cell proliferation, cell cycle, cell apoptosis...

Effect of statins on preventing infectious complications after surgery: Systematic review and meta-analysis

Objective A meta-analysis to investigate the association between preoperative statin use and the risk of postoperative infectious complications in patients undergoing surgery.

Mobility of the first metatarsal-cuneiform joint in patients with and without hallux valgus: in vivo three-dimensional analysis using computerized tomography scan

computerized tomography scan Xiang Geng 0 Chen Wang 0 Xin Ma Xu Wang Jiazhang Huang Chao Zhang Jian Xu Junsheng Yang 0 Equal contributors Department of Orthopedics, Huashan Hospital, Fudan University , 12

Sol-gel synthesis and third-order optical nonlinearity of Au nanoparticles doped monolithic glass

Gold nanoparticles (Au NPs) doped monolithic and transparent sodium borosilicate glass has been synthesized by both sol-gel and atmosphere control heat treatment methods. Fourier transform infrared (FTIR) spectra in the wavenumber range of 400 to 4000 cm−1 were applied to collect variation information of surface groups of the samples in the sintering process. The microstructure...

The Silk Road Health Project: How Mobility and Migration Status Influence HIV Risks among Male Migrant Workers in Central Asia

Objectives We examined whether mobility, migrant status, and risk environments are associated with sexually transmitted infections (STIs) and HIV risk behaviors (e.g. sex trading, multiple partners, and unprotected sex). Methods We used Respondent Driven Sampling (RDS) to recruit external male migrant market vendors from Kyrgyzstan, Uzbekistan, and Tajikistan as well internal...

A Collaborative Professional Development Approach to Improving Student Outcomes

, University of Louisville Eve Proffitt, University of Kentucky, P-20 Innovation Lab Tom Guskey, University of Kentucky Xin Ma, University of Kentucky Abstract The purpose of this article is to analyze the