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Search: authors:"Xine Shen"

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Methamphetamine-induced changes in the striatal dopamine pathway in μ-opioid receptor knockout mice

Background Repeated exposure to methamphetamine (METH) can cause not only neurotoxicity but also addiction. Behavioral sensitization is widely used as an animal model for the study of drug addiction. We previously reported that the μ-opioid receptor knockout mice were resistant to METH-induced behavioral sensitization but the mechanism is unknown. Methods The present study ...