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Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes. We conducted a multicenter...

Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: a clinical practice change

 Shaw2, Aaron Le Compte1Email author, Timothy Lonergan1, Michael Willacy1, Xing-Wei Wong1, Jessica Lin1, Thomas Lotz1, Dominic Lee3 and Christopher Hann1 Critical Care200812:R49 https://doi.org/10.1186

Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: a clinical practice change

Introduction Stress-induced hyperglycaemia is prevalent in critical care. Control of blood glucose levels to within a 4.4 to 6.1 mmol/L range or below 7.75 mmol/L can reduce mortality and improve clinical outcomes. The Specialised Relative Insulin Nutrition Tables (SPRINT) protocol is a simple wheel-based system that modulates insulin and nutritional inputs for tight glycaemic...