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Search: authors:"Xinsheng Liu"

4 papers found.
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Detection and phylogenetic analyses of spike genes in porcine epidemic diarrhea virus strains circulating in China in 2016–2017

Large-scale outbreaks of porcine epidemic diarrhea (PED) have re-emerged in China in recent years. However, little is known about the genetic diversity and molecular epidemiology of field strains of PED virus (PEDV) in China in 2016–2017. To address this issue, in this study, 116 diarrhea samples were collected from pig farms in 6 Chinese provinces in 2016–2017 and were detected ...

Swamping and masking in Markov boundary discovery

This paper considers the problems of swamping and masking in Markov boundary discovery for a target variable. There are two potential reasons for swamping and masking: one is incorrectness of some conditional independence (CI) tests, and the other is violation of local composition. First, we explain why the incorrectness of CI tests may lead to swamping and masking, analyze how to ...

Experimental infection of a US spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infection

Although the original US porcine epidemic diarrhea virus (PEDV) was confirmed as highly virulent by multiple studies, the virulence of spike-insertion deletion (S-INDEL) PEDV strains is undefined. In this study, 3–4 day-old conventional suckling piglets were inoculated with S-INDEL PEDV Iowa106 (4 pig litters) to study its virulence. Two litters of age-matched piglets were ...

Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain

The infectious dose of a virus pool of original US PEDV strain PC22A was determined in 4-day-old, cesarean-derived, colostrum-deprived (CDCD) piglets. The median pig diarrhea dose (PDD 50 ) of the virus pool was determined as 7.35 log 10 PDD 50 /mL, similar to the cell culture infectious titer, 7.75 log 10 plaque-forming units (PFU)/mL. 100 PDD 50 caused watery diarrhea in all ...