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Diagnostic performance evaluation of different TI-RADS using ultrasound computer-aided diagnosis of thyroid nodules: An experience with adjusted settings

: Nonhlanhla Chambara, Shirley Y. W. Liu, Xina Lo, Michael Ying. Methodology: Nonhlanhla Chambara, Michael Ying. Resources: Shirley Y. W. Liu, Xina Lo, Michael Ying. Validation: Shirley Y. W. Liu, Xina Lo ... , Michael Ying. Visualization: Nonhlanhla Chambara. Writing – original draft: Nonhlanhla Chambara. Writing – review & editing: Nonhlanhla Chambara, Shirley Y. W. Liu, Xina Lo, Michael Ying. 12 / 14 13

Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics Investigation of Neurodevelopmental Migratory Pathways

Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of neurodevelopmental migratory pathways, possibly triggered by febrile seizures. This study aims to compare the proteomes of...

Doublecortin-expressing cell types in temporal lobe epilepsy

Doublecortin (DCX) is widely regarded as a marker of immature and migrating neurons during development. While DCX expression persists in adults, particularly in the temporal lobe and neurogenic regions, it is unknown how seizures influence its expression. The aim of the present study was to explore the distribution and characteristics of DCX-expressing cells in surgical and...

Environmental controls on the boron and strontium isotopic composition of aragonite shell material of cultured Arctica islandica

to Y.-W. Liu and from the Packard Foundation to S. M. Aciego. We thank Tsuyoshi Watanabe, Hokkaido University, Japan for providing an aliquot of the international coral standard (JCp-1). Edited by: D

Computer-aided assessment of regional vascularity of thyroid nodules for prediction of malignancy

Color Doppler vascular index (VI) was assessed alone and in combination with grey-scale ultrasound (GSU) in regionally subdivided thyroid nodules in diagnosing thyroid cancer. Color Doppler sonograms of 111 thyroid nodules were evaluated by a home-developed algorithm that performed “offsetting” (algorithm for changing the area of a region of interest, ROI, without distorting the...

Redetermination of the strong-interaction width in pionic hydrogen

. Hennebach 3 12 P. Indelicato 13 Th. S. Jensen 4 9 14 E.-O. Le Bigot 13 Y.-W. Liu 5 9 V. E. Markushin 9 J. Marton 7 M. Nekipelov 6 12 J. M. F. dos Santos 10 L. M. Simons 9 Th. Strauch 12 M. Trassinelli 15 J

Tumour exosomes from cells harbouring PTPRZ1–MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma

Exosomes are carriers of pro-tumorigenic factors that participate in glioblastoma (GBM) progression, and many fusion genes are strong driver mutations in neoplasia and are involved in tumorigenesis. However, the ability of fusion genes to be transduced by exosomes is unknown. We characterized exosomes from GBM cells harbouring and not harbouring PTPRZ1–MET fusion (ZM fusion). We...

EGb761 improves histological and functional recovery in rats with acute spinal cord contusion injury

Study design:This is an experimental study.Objectives:The objective of this study was to evaluate the neuroprotective effects of Ginkgo biloba extract 761 (EGb761) on histological features of injured sites and on functional performance of rats subjected to standardized spinal cord injury (SCI).Setting:This study was conducted in Xian, Shaanxi, China.Methods:Thirty female Sprague...

Neuropathology of 16p13.11 Deletion in Epilepsy

16p13.11 genomic copy number variants are implicated in several neuropsychiatric disorders, such as schizophrenia, autism, mental retardation, ADHD and epilepsy. The mechanisms leading to the diverse clinical manifestations of deletions and duplications at this locus are unknown. Most studies favour NDE1 as the leading disease-causing candidate gene at 16p13.11. In epilepsy at...

Long-term survival outcomes after definitive chemoradiation versus surgery in patients with resectable squamous carcinoma of the esophagus: results from a randomized controlled trial

Background The aim of this study was to report on the 5-year survival outcomes of patients with resectable esophageal carcinoma who were treated by definitive chemoradiotherapy (CRT) or standard esophagectomy.

Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B

for K-C Chang in:Nature Research journals • PubMed • Google ScholarSearch for Y-W Liu in:Nature Research journals • PubMed • Google ScholarSearch for J T Tseng in:Nature Research journals • PubMed

A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells

Znf179 is a member of the RING finger protein family. During embryogenesis, Znf179 is expressed in a restricted manner in the brain, suggesting a potential role in nervous system development. In this report, we show that the expression of Znf179 is upregulated during P19 cell neuronal differentiation. Inhibition of Znf179 expression by RNA interference significantly attenuated...

Experiments towards resolving the proton charge radius puzzle

We review the status of the proton charge radius puzzle. Emphasis is given to the various experiments initiated to resolve the conflict between the muonic hydrogen results and the results from scattering and regular hydrogen spectroscopy.

Is the proton radius a player in the redefinition of the International System of Units?

It is now recognized that the International System of Units (SI units) will be redefined in terms of fundamental constants, even if the date when this will occur is still under debate. Actually, the best estimate of fundamental constant values is given by a least-squares adjustment, carried out under the auspices of the Committee on Data for Science and Technology (CODATA) Task...