Advanced search    

Search: authors:"Yan Huang"

167 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Nonclinical comparability studies of recombinant human arylsulfatase A addressing manufacturing process changes

: Teresa Wright. Formal analysis: Aiqun Li, Anne-Renee Graham, Jing Pan. Investigation: Aiqun Li, Jason Lotterhand, Anne-Renee Graham, Yan Huang, Nancy Avila, Jing Pan. Supervision: Teresa Wright ... . Writing ± original draft: Teresa Wright, Aiqun Li, Jason Lotterhand, Anne-Renee Graham, Yan Huang, Nancy Avila, Jing Pan. Writing ± review & editing: Teresa Wright, Aiqun Li, Jason Lotterhand, Anne-Renee

On climate prediction: how much can we expect from climate memory?

Slowing variability in climate system is an important source of climate predictability. However, it is still challenging for current dynamical models to fully capture the variability as well as its impacts on future climate. In this study, instead of simulating the internal multi-scale oscillations in dynamical models, we discussed the effects of internal variability in terms of...

Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis

from the Biomedical Laboratory Research and Development Program of the Department of Veterans Affairs (Yan Huang) and NIH grant DE016353 (Yan Huang). The funders had no role in study design, data ... Huang. Formal analysis: Junfei Jin, Zhongyang Lu, Yanchun Li, L. Ashley Cowart, Maria F. Lopes Virella, Yan Huang. Funding acquisition: Yan Huang. Investigation: Junfei Jin, Zhongyang Lu, Yanchun Li

Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer

Clinically, prostate cancer (PCa) exhibits a high avidity to metastasize to bone. miR-141-3p is an extensively studied miRNA in cancers and downregulation of miR-141-3p has been widely reported to be involved in the progression and metastasis of several human cancer types. However, the clinical significance and biological roles of miR-141-3p in bone metastasis of PCa are still...

Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer

Clinically, prostate cancer (PCa) exhibits a high avidity to metastasize to bone. miR-141-3p is an extensively studied miRNA in cancers and downregulation of miR-141-3p has been widely reported to be involved in the progression and metastasis of several human cancer types. However, the clinical significance and biological roles of miR-141-3p in bone metastasis of PCa are still...

Investigating the cross-lingual translatability of VerbNet-style classification

VerbNet—the most extensive online verb lexicon currently available for English—has proved useful in supporting a variety of NLP tasks. However, its exploitation in multilingual NLP has been limited by the fact that such classifications are available for few languages only. Since manual development of VerbNet is a major undertaking, researchers have recently translated VerbNet...

Error model of geomagnetic-field measurement and extended Kalman-filter based compensation method

The real-time accurate measurement of the geomagnetic-field is the foundation to achieving high-precision geomagnetic navigation. The existing geomagnetic-field measurement models are essentially simplified models that cannot accurately describe the sources of measurement error. This paper, on the basis of systematically analyzing the source of geomagnetic-field measurement error...

Residual volume/total lung capacity ratio confers limited additive significance to lung clearance index for assessment of adults with bronchiectasis

-jie Guan, Rong-chang Chen, Nan-shan Zhong. Data curation: Wei-jie Guan, Jing-jing Yuan, Yan Huang. Formal analysis: Wei-jie Guan. Funding acquisition: Wei-jie Guan, Rong-chang Chen, Nan-shan Zhong ... . Investigation: Wei-jie Guan, Jing-jing Yuan, Yan Huang, Hui-min Li. Methodology: Wei-jie Guan, Jing-jing Yuan, Yan Huang, Hui-min Li. Project administration: Wei-jie Guan. Resources: Hui-min Li, Nan-shan Zhong

LsrB-based and temperature-dependent identification of bacterial AI-2 receptor

The luxS gene is required for autoinducer-2 (AI-2) synthesis in many bacterial species. AI-2 is taken up by a specific receptor to regulate multiple bacterial activities. However, the lack of methods to identify AI-2 receptors has impeded investigations into the roles of AI-2. Here, a luxS mutant of Escherichia coli strain BL21 (DE3) was constructed (named BL21∆luxS), and the...

Lactate dehydrogenase and creatine kinase as poor prognostic factors in lung cancer: A retrospective observational study

: Huairong Tang, Weimin Li, Li Zhang. Data curation: Lei Liu, Ying He, Ge Ge, Lei Li, Ping Zhou, Yihan Zhu, Yan Huang. Formal analysis: Lei Liu. Investigation: Ying He. Methodology: Lei Liu, Lei Li, Ping ... Zhou, Yihan Zhu, Huairong Tang, Yan Huang. 14 / 16 Resources: Lei Liu. Software: Lei Liu, Ge Ge. Supervision: Li Zhang. Validation: Huairong Tang, Weimin Li. Visualization: Lei Liu. Writing

ARN: analysis and prediction by adipogenic professional database

Adipogenesis is the process of cell differentiation by which mesenchymal stem cells become adipocytes. Extensive research is ongoing to identify genes, their protein products, and microRNAs that correlate with fat cell development. The existing databases have focused on certain types of regulatory factors and interactions. However, there is no relationship between the results of...

Pyridoxine Supplementation Improves the Activity of Recombinant Glutamate Decarboxylase and the Enzymatic Production of Gama-Aminobutyric Acid

Glutamate decarboxylase (GAD) catalyzes the irreversible decarboxylation of L-glutamate to the valuable food supplement γ-aminobutyric acid (GABA). In this study, GAD from Escherichia coli K12, a pyridoxal phosphate (PLP)-dependent enzyme, was overexpressed in E. coli. The GAD produced in media supplemented with 0.05 mM soluble vitamin B6 analog pyridoxine hydrochloride (GAD-V...

The association of long-term glycaemic variability versus sustained chronic hyperglycaemia with heart rate-corrected QT interval in patients with type 2 diabetes

acquisition: Jian-bin Su, Xing-bo Cheng, Xue-qin Wang. Investigation: Jian-bin Su, Xiao-hua Yang, Xiu-lin Zhang, Hong-li Cai, Hai-yan Huang. Methodology: Jian-bin Su. Project administration: Jian-bin Su ... , Xing-bo Cheng, Xue-qin Wang. Resources: Hai-yan Huang, Li-hua Zhao, Feng Xu, Tong Chen. Supervision: Jian-bin Su, Xing-bo Cheng, Yan Lu. Validation: Jian-bin Su, Xiao-hua Yang, Hai-yan Huang, Tong

A prospective study of breast anthropomorphic measurements, volume and ptosis in 605 Asian patients with breast cancer or benign breast disease

Objectives The current study aims to summarize breast anthropomorphic measurement features in Chinese patients with breast diseases and to investigate their potential correlations with demographic factors. Materials and methods Fifteen breast anthropomorphic parameters of 605 Chinese female patients were collected prospectively. Breast ptosis status was scaled by two methods and...

Hepatitis B virus X protein in liver tumor microenvironment

Encoded by the hepatitis B virus, hepatitis B virus X protein (HBx) is a multifunctional, potentially oncogenic protein that acts primarily during the progression from chronic hepatitis B to cirrhosis and hepatocellular carcinoma (HCC). In recent decades, it has been established that chronic inflammation generates a tumor-supporting microenvironment. HCC is a typical chronic...