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71 papers found.
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Mechanistic insight into the interaction of gastrointestinal mucus with oral diblock copolymers synthesized via ATRP method

Mechanistic insight into the interaction of gastrointestinal mucus with oral diblock copolymers synthesized via ATRP method Jiao Liu,1,* Jie Cao,1,* Jianhua Cao,2 Shangcong Han,1 Yan Liang,1 Mingfeng ... (ww.tcpdf.org) O r I g I N a l r e s e a r c h Jianhua cao 2 shangcong han 1 Yan liang 1 Yong sun 1 Introduction: Nanoparticles are increasingly used as drug carriers for oral administration. The delivery of drug

Revisiting radiative decays of \(1^{+-}\) heavy quarkonia in the covariant light-front approach

We revisit the calculation of the width for the radiative decay of a \(1^{+-}\) heavy \(Q \bar{Q}\) meson via the channel \(1^{+-} \rightarrow 0^{-+} +\gamma \) in the covariant light-front quark model. We carry out the reduction of the light-front amplitude in the non-relativistic limit, explicitly computing the leading and next-to-leading order relativistic corrections. This...

Combination of twelve alleles at six quantitative trait loci determines grain weight in rice

, Zhijuan Ji, Zhihua Wen, Yan Liang. Funding acquisition: Changdeng Yang. Investigation: Yuxiang Zeng, Zhijuan Ji, Zhihua Wen, Yan Liang. Project administration: Changdeng Yang. Resources: Junsheng Shi

Up-regulation of lncRNA CASC9 promotes esophageal squamous cell carcinoma growth by negatively regulating PDCD4 expression through EZH2

Abnormal expression of numerous long non-coding RNAs (lncRNAs) has been reported in esophageal squamous cell carcinoma (ESCC) recently, but the great majority of their roles and mechanisms remain largely unclear. We aim to identify the critical ESCC-associated lncRNAs and elucidate the functions and mechanisms in detail. Microarrays were used to analyze the differentially...

Hemostatic chemical constituents from natural medicine Toddalia asiatica root bark by LC-ESI Q-TOF MSE

Background Toddalia asiatica root bark as an effective hemostatic natural medicine or Chinese materia medica was applied in China for long history, its complex drug action mechanisms and unclear substance basis have been constraining the development of this drug. Results An intelligentized strategy by LC-ESI Q-TOF MSE was presented in this study for rapid identification of...

Transcriptomic profiling in muscle and adipose tissue identifies genes related to growth and lipid deposition

(www.liwenbianji.cn/ac), for editing the English Yiren Gu, Xuebin Lv. Gu, Xuebin Lv. Conceptualization: Xuan Tao, Yan Liang, Yiren Gu, Xuebin Lv. Formal analysis: Xuan Tao, Yan Liang, Xuemei Yang, Yiren Gu, Xuebin ... Lv. Funding acquisition: Yiren Gu, Xuebin Lv. Investigation: Xuan Tao, Yan Liang, Xuemei Yang, Jianhui Pang, Zhijun Zhong, Xiaohui Chen, Yuekui Yang, Kai Zeng, Runming Kang, Yunfeng Lei, Sancheng

Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer

Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer Yan Liang,1 Baocheng Tian,1 Jing

SlMAPK3 enhances tolerance to tomato yellow leaf curl virus (TYLCV) by regulating salicylic acid and jasmonic acid signaling in tomato (Solanum lycopersicum)

Several recent studies have reported on the role of mitogen-activated protein kinase (MAPK3) in plant immune responses. However, little is known about how MAPK3 functions in tomato (Solanum lycopersicum L.) infected with tomato yellow leaf curl virus (TYLCV). There is also uncertainty about the connection between plant MAPK3 and the salicylic acid (SA) and jasmonic acid (JA...

Plasma fibrin D-dimer and the risk of left atrial thrombus: A systematic review and meta-analysis

Background Plasma fibrin d-dimer has been taken as a marker for thrombus. The aim of this study was to evaluate the relationship between d-dimer (DD) levels and left atrial spontaneous echo contrast (SEC)/left atrial thrombus (LAT). Methods We identified clinical studies by systematic search of MEDLINE and EMBASE databases up to Feb 2016. All observational studies that considered...

Combination of Eight Alleles at Four Quantitative Trait Loci Determines Grain Length in Rice

Grain length is an important quantitative trait in rice (Oryza sativa L.) that influences both grain yield and exterior quality. Although many quantitative trait loci (QTLs) for grain length have been identified, it is still unclear how different alleles from different QTLs regulate grain length coordinately. To explore the mechanisms of QTL combination in the determination of...

Deviating from the nanorod shape: Shape-dependent plasmonic properties of silver nanorice and nanocarrot structures

Noble metallic nanostructures exhibit special optical properties resulting from excitation of surface plasmons. Among the various metallic nanostructures, nanorods have attracted particular attention because of their unique and intriguing shape-dependent plasmonic properties. Nanorods can support transverse and longitudinal plasmon modes, the latter ones depending strongly on the...

Response to: ‘Body mass index and the risk of rheumatoid arthritis: a systematic review and dose–response meta-analysis’ - authors’ reply

Liang 0 Zaixing Yang 0 Renqian Zhong 0 0 Department of Laboratory Diagnostics, Changzheng Hospital, Second Military Medical University , 415 Fengyang Road, Shanghai , China © 2015 Qin et al. Open Access

The Combined Effects of Arbuscular Mycorrhizal Fungi (AMF) and Lead (Pb) Stress on Pb Accumulation, Plant Growth Parameters, Photosynthesis, and Antioxidant Enzymes in Robinia pseudoacacia L.

Arbuscular mycorrhizal fungi (AMF) are considered as a potential biotechnological tool for improving phytostabilization efficiency and plant tolerance to heavy metal-contaminated soils. However, the mechanisms through which AMF help to alleviate metal toxicity in plants are still poorly understood. A greenhouse experiment was conducted to evaluate the effects of two AMF species...

Tight regulation of plant immune responses by combining promoter and suicide exon elements

Effector-triggered immunity (ETI) is activated when plant disease resistance (R) proteins recognize the presence of pathogen effector proteins delivered into host cells. The ETI response generally encompasses a defensive ‘hypersensitive response’ (HR) that involves programmed cell death at the site of pathogen recognition. While many R protein and effector protein pairs are known...

The Association of 5-HT2A, 5-HTT, and LEPR Polymorphisms with Obstructive Sleep Apnea Syndrome: A Systematic Review and Meta-Analysis

Objective A consensus has not been reached regarding the association of several different gene polymorphisms and susceptibility to obstructive sleep apnea syndrome (OSAS). We performed a meta-analysis to better evaluate the associations between 5-HT2A, 5-HTT, and LEPR polymorphisms, and OSAS. Method 5-HT2A, 5-HTT, and LEPR polymorphisms and OSAS were identified in PubMed and...

Association between Lipid Ratios and Insulin Resistance in a Chinese Population

Aim To explore the association of lipid ratios and triglyceride (TG) with insulin resistance (IR) in a Chinese population. We also provide the clinical utility of lipid ratios to identify men and women with IR. Methods This cross-sectional study included 614 men and 1055 women without diabetes. Insulin resistance was defined by homeostatic model assessment of IR > 2.69. Lipid...

Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling

Unraveling the mechanisms underlying early neural differentiation of embryonic stem cells (ESCs) is crucial to developing cell-based therapies of neurodegenerative diseases. Neural fate acquisition is proposed to be controlled by a ‘default’ mechanism, for which the molecular regulation is not well understood. In this study, we investigated the functional roles of Mediator Med23...

Effects of Warming on CO2 Fluxes in an Alpine Meadow Ecosystem on the Central Qinghai–Tibetan Plateau

To analyze CO2 fluxes under conditions of climate change in an alpine meadow on the central Qinghai–Tibetan Plateau, we simulated the effect of warming using open top chambers (OTCs) from 2012 to 2014. The OTCs increased soil temperature by 1.62°C (P < 0.05), but decreased soil moisture (1.38%, P < 0.05) during the experiments. The response of ecosystem CO2 fluxes to warming was...

The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

Chitin is a fungal microbe-associated molecular pattern recognized in Arabidopsis by a lysin motif receptor kinase (LYK), AtCERK1. Previous research suggested that AtCERK1 is the major chitin receptor and mediates chitin-induced signaling through homodimerization and phosphorylation. However, the reported chitin binding affinity of AtCERK1 is quite low, suggesting another...