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Concrete surface crack detection with the improved pre-extraction and the second percolation processing methods

. Software: Zhong Qu, Fang-Rong Ju, Yang Guo, Ling Bai, Kuo Chen. Visualization: Yang Guo, Ling Bai, Kuo Chen. Writing ± original draft: Zhong Qu, Fang-Rong Ju, Yang Guo, Ling Bai, Kuo Chen. Writing ± review

Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-κB pathway

OncoTargets and Therapy long noncoding rna nea T1 promotes nasopharyngeal carcinoma progression through regulation of mir-124/nF- κB pathway n an cheng 1 Yang guo 0 0 Department of Ophthalmology

Efficacy differences of electroacupuncture with single acupoint or matching acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial

Previous studies have shown that acupuncture is beneficial for the alleviation of chemotherapy-induced nausea and vomiting. However, there is a lack of clinical evidence concerning the effects of acupoint-matching on chemotherapy-induced nausea and vomiting. This is a parallel randomized controlled trial to evaluate the occurrence of nausea and vomiting after chemotherapy (the...

Current status and future prospects of mesenchymal stem cell therapy for liver fibrosis

Hospital, School of Medicine, Zhejiang University , Hangzhou 310003 , China) 1 Project supported by the National High-Tech R & D Program (863) of China (No. 2015AA020306) ORCID: Yang GUO Liver fibrosis is ... . Compliance with ethics guidelines Yang GUO, Bo CHEN, Li-jun CHEN, Chun-feng ZHANG, and Charlie XIANG declare that they have no conflict of interest. This article does not contain any studies with human or

Magnetic Helicity Estimations in Models and Observations of the Solar Magnetic Field. Part I: Finite Volume Methods

Magnetic helicity is a conserved quantity of ideal magneto-hydrodynamics characterized by an inverse turbulent cascade. Accordingly, it is often invoked as one of the basic physical quantities driving the generation and structuring of magnetic fields in a variety of astrophysical and laboratory plasmas. We provide here the first systematic comparison of six existing methods for...

Dexmedetomidine versus remifentanil for sedation during awake intubation using a Shikani optical stylet: a randomized, double-blinded, controlled trial

0 Cheng Ni 0 Xiang-yang Guo 0 0 Department of Anesthesiology, Peking University Third Hospital , Beijing 100191 , China Background: The purpose of this study was to compare the efficacy and safety of

VideoMap: An interactive and scalable visualization for exploring video content

VideoMap: An interactive exploring video content Cui-Xia Ma Yang Guo Hong-An Wang Large-scale dynamic relational data visualization has attracted considerable research attention recently. We ... , China, in 2003. She is now a professor with the Institute of Software, Chinese Academy of Sciences. Her research interests include human–computer interaction and multimedia computing. Yang Guo started

Low-Density Granulocytes Are Elevated in Mycobacterial Infection and Associated with the Severity of Tuberculosis

Tuberculosis remains a global health problem caused by infection with Mycobacterium tuberculosis. Numerous studies have established a close correlation between the development of tuberculosis and the roles of neutrophils. Recently, a distinct population of CD15+ granulocytes was found to be present in the peripheral blood mononuclear cell (PBMC) fraction in humans. This...

PD-L1-expressing neutrophils as a novel indicator to assess disease activity and severity of systemic lupus erythematosus

Background It is well-known that increased frequency of neutrophils was found in patients with systemic lupus erythematosus (SLE). However, the immunomodulatory roles and mechanisms of neutrophils in SLE are poorly understood. Methods Patients with SLE were recruited from the First Affiliated Hospital of Nanchang University. The medical history, clinical manifestations, physical...

Ultrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors

Chen-Yang Guo,2 Wei Zhang,1 Zhi-Ping Yan,1 Rong Liu,1 Jian-Hua Wang1 1Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of ... scientific and medical research O r i g i n a l r e s e a r c h cheng-shi chen 1,2,* chen-Yang guo 2 *These authors contributed equally to this work Introduction Transarterial chemoembolization (TACE) and

Effects of two different anesthesia-analgesia methods on incidence of postoperative delirium in elderly patients undergoing major thoracic and abdominal surgery: study rationale and protocol for a multicenter randomized controlled trial

Background Delirium is a common complication in elderly patients after surgery and associated with increased morbidity and mortality. Studies suggest that deep anesthesia and intense pain are important precipitating factors of postoperative delirium. Neuraxial block is frequently used in combination with general anesthesia for patients undergoing major thoracic and abdominal...

Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation

Over activation of microglia results in the production of proinflammatory agents that have been implicated in various brain diseases. Pycnogenol is a patented extract from French maritime pine bark (Pinus pinaster Aiton) with strong antioxidant and anti-inflammatory potency. The present study investigated whether pycnogenol may be associated with the production of proinflammatory...

Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro

The tuberculous granuloma is an elaborately organized structure and one of the main histological hallmarks of tuberculosis. Macrophages, which are important immunologic effector and antigen-presenting cells, are the main cell type found in the tuberculous granuloma and have high plasticity. Macrophage polarization during bacterial infection has been elucidated in numerous recent...

Renal Denervation Suppresses Atrial Fibrillation in a Model of Renal Impairment

Background A close association exists between renal impairment (RI) and atrial fibrillation (AF) occurrence. Increased activity of the sympathetic nervous system (SNS) may contribute to the development of AF associated with RI. Renal denervation (RDN) decreases central sympathetic activity. Objective The main objective of the study was to explore the effects of RDN on AF...

Soluble LRIG2 Ectodomain Is Released from Glioblastoma Cells and Promotes the Proliferation and Inhibits the Apoptosis of Glioblastoma Cells In Vitro and In Vivo in a Similar Manner to the Full-Length LRIG2

The human leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family contains LRIG1, 2 and 3, encoding integral membrane proteins with an ectodomain, a transmembrane domain and a cytoplasmic tail. LRIG1 negatively regulates multiple receptor tyrosine kinases signaling including the epidermal growth factor receptor (EGFR) and is a proposed tumor suppressor. The...

Establishment of a Model of Renal Impairment with Mild Renal Insufficiency Associated with Atrial Fibrillation in Canines

Background Chronic kidney disease and occurrence of atrial fibrillation (AF) are closely related. No studies have examined whether renal impairment (RI) without severe renal dysfunction is associated with the occurrence of AF. Methods Unilateral RI with mild renal insufficiency was induced in beagles by embolization of small branches of the renal artery in the left kidney for 2...

Characterization and Evolutionary Implications of the Triad Asp-Xxx-Glu in Group II Phosphopantetheinyl Transferases

Phosphopantetheinyl transferases (PPTases), which play an essential role in both primary and secondary metabolism, are magnesium binding enzymes. In this study, we characterized the magnesium binding residues of all known group II PPTases by biochemical and evolutionary analysis. Our results suggested that group II PPTases could be classified into two subgroups, two-magnesium...

β2-Adrenoceptor Involved in Smoking-Induced Airway Mucus Hypersecretion through β-Arrestin-Dependent Signaling

Progression of chronic obstructive pulmonary disease is associated with small airway obstruction by accumulation of inflammatory mucous exudates. However, the mechanism of mucin hypersecretion after exposure to cigarette smoke (CS) is still not clear. In this study, we explored the contribution of β2-adrenoceptor (β2-AR) signaling to CS extract (CSE)-induced mucus hypersecretion...

Human rabies surveillance and control in China, 2005–2012

Background Rabies reemerged in China during the 1990s with a gradual increase in the number and geographical dispersion of cases. As a consequence, a national surveillance program was introduced in 2005 to investigate the outbreak in terms of vaccination coverage, PEP treatment, and geographical and social composition. Methods The surveillance program was coordinated at the...