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107 papers found.
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Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects

Madhura Kulkarni in:Nature Research journals • PubMed • Google Scholar Search for Yang Shen in:Nature Research journals • PubMed • Google Scholar Search for Kah. J. Lim in:Nature Research journals

Conventional and transepithelial corneal cross-linking for patients with keratoconus

± original draft: Mi Tian, Yang Shen. Writing ± review & editing: Yang Shen. 12 / 15 13 / 15 14 / 15 1. Vazirani J , Basu S. Keratoconus: current perspectives . Clinical ophthalmology . 2013 ; 7: 2019 ±30

Color sensors and their applications based on real-time color image segmentation for cyber physical systems

Color information plays an important role in the color image segmentation and real-time color sensor, which affects the result of video image segmentation and correct real-time temperature value. In this paper, a novel real-time color image segmentation method is proposed, which is based on color similarity in RGB color space. According to the color and luminance information in...

Macro-meso effects of gradation and particle morphology on the compressibility characteristics of calcareous sand

In order to fully develop the South China Sea, a large number of reclamation projects using calcareous sand have been carried out in this area recently. A deep understanding of the physical and mechanical properties of calcareous sand is of critical importance. Therefore, the calcareous sand near a certain reef of the South China Sea is used in this study to investigate the...

An analytical solution for two-dimensional vacuum preloading combined with electro-osmosis consolidation using EKG electrodes

the Central Universities (2015B17114). Author Contributions Conceptualization: Yang Shen, Chenchen Qiu, Wen Shi, Xiaoxi Rui. Data curation: Yang Shen, Chenchen Qiu, Wen Shi, Xiaoxi Rui. Investigation ... : Yang Shen, Chenchen Qiu. 14 / 15 Project administration: Yande Li. Resources: Yang Shen, Chenchen Qiu, Wen Shi, Xiaoxi Rui. Writing ± original draft: Chenchen Qiu, Wen Shi, Xiaoxi Rui. Writing ± review

The absence of N-acetylglucosamine in wall teichoic acids of Listeria monocytogenes modifies biofilm architecture and tolerance to rinsing and cleaning procedures

Faille. Resources: Yang Shen, Martin J. Loessner. Supervision: Graziella Midelet-Bourdin. Validation: Irina Sadovskaya, Graziella Midelet-Bourdin. Visualization: Alain Charbit, Thierry Benezech, Yang ... Benezech, Yang Shen, Martin J. Loessner, Graziella Midelet-Bourdin. 17 / 19 MBio. 2014; 5(3):e00880±14. Epub 2014/05/08. https://doi.org/10.1128/mBio.00880-14 PMID: 24803515 18 / 19 1. Swaminathan B

Prevalence and risk factors associated with hypertension and prehypertension in a working population at high altitude in China: a cross-sectional study

Background Little information is available on the epidemiology of hypertension and prehypertension at high altitude in China, the aim of this study was to determine the prevalence of hypertension, prehypertension and their risk factors among Chinese working population at high altitude regions. Methods A cross-sectional survey was performed in an occupational sample of 4198...

cNMA: a framework of encounter complex-based normal mode analysis to model conformational changes in protein interactions

Motivation: It remains both a fundamental and practical challenge to understand and anticipate motions and conformational changes of proteins during their associations. Conventional normal mode analysis (NMA) based on anisotropic network model (ANM) addresses the challenge by generating normal modes reflecting intrinsic flexibility of proteins, which follows a conformational...

Effects of Initial Concentration on Flocculation Size and Settling Velocity of Marine Hydraulic Fill Clay

Using marine hydraulic fill clay to reclaim land is the main mean to deal with land supply and demand in coastal area. Detecting the soil’s settling velocity, which is mainly affected by initial concentration of clay, is significant for filling projects. In this paper the marine clay of the East China Sea was used for tests to study the floc size and the settling velocity...

Liver resection for hepatocellular carcinoma in patients with hematological malignancies

Improvements in antimetabolite drugs have prolonged the survival of patient with hematological malignancies. However, these drugs may have hepatotoxic side effects and may induce acute liver failure, chronic liver fibrosis, cirrhosis, or even hepatocellular carcinoma (HCC). Although liver resection remains a curative option for HCC, its role in HCC with hematological malignancies...

Adsorption of Pb(II) by Activated Pyrolytic Char from Used Tire

As a renewable resource, the pyrolytic char derived from used tire has promising adsorption capacities owing to its similar structure and properties with active carbon. The purification and activation of the pyrolytic char from used tire, as well as the application of this material in the adsorption of Pb(II) in water is conducted. The influences on the adsorption capacity by...

Location and moment tensor inversion of small earthquakes using 3D Green’s functions in models with rugged topography: application to the Longmenshan fault zone

With dense seismic arrays and advanced imaging methods, regional three-dimensional (3D) Earth models have become more accurate. It is now increasingly feasible and advantageous to use a 3D Earth model to better locate earthquakes and invert their source mechanisms by fitting synthetics to observed waveforms. In this study, we develop an approach to determine both the earthquake...

Changes in intraocular pressure values measured with noncontact tonometer (NCT), ocular response analyzer (ORA) and corvis scheimpflug technology tonometer (CST) in the early phase after small incision lenticule extraction (SMILE)

of the manuscript. Availability of data and materials Available upon request from the co-first authors Yang Shen and Xiangjian Su. Authors’ contributions YS and XJS were the major contributors in

A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study

Background Early repolarization syndrome (ERS) may be a near-Mendelian or an oligogenic disease; however, no direct evidence has been provided to support this theory. Methods and results We described a large Chinese family with nocturnal sudden cardiac death induced by ERS in most of the young male adults. One missense mutation (p.Q1916R) was found in the major subunit of the L...

Clinical and prognostic analysis of 78 patients with human immuno-deficiency virus associated non-Hodgkin’s lymphoma in Chinese population

Background Human Immuno-deficiency Virus (HIV) associated non-Hodgkin’s lymphoma (NHL) was a special group of disease, which manifests distinct clinical features and prognosis as compared with NHLs in patients without HIV. We performed this study to describe the clinical features of the disease and investigated the potential prognostic factors. Methods HIV-infected patients who...

Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats

Background We determined whether bone marrow mesenchymal stem cells (BMMSCs) transduced with heme oxygenase-1 (HO-1), a cytoprotective and immune-protective factor, could improve outcomes for small bowel transplantation (SBTx) in rats. Methods We performed heterotopic SBTx from Brown Norway rats to Lewis rats, before infusing Ad/HO-1-transduced BMMSCs (Ad/HO-1/BMMSCs) through the...

Food Emulsifier Glycerin Monostearate Increases Internal Exposure Levels of Six Priority Controlled Phthalate Esters and Exacerbates Their Male Reproductive Toxicities in Rats

Human beings are inevitably exposed to ubiquitous phthalate esters (PAEs). Processed, packaged foods are popular nowadays, in which emulsifiers are frequently added as food additives. It is unclear how emulsifiers affect the bioavailability of ingested PAEs contaminants and their toxicities. The purposes of our study were to explore whether food emulsifier Glycerin Monostearate...

SNAP23 promotes the malignant process of ovarian cancer

Background Ovarian cancer (OC) was the primary malignant gynecological cancer and SNARE protein is closely related with tumor progression. Here, we identified SNAP23, a member of SNARE complex, as a potential oncogene in OC. Methods We determined the expression of SNAP23 in OC tissues and explored the clinical significance through bioinformatics analysis. The effects of SNAP23 on...