Advanced search    

Search: authors:"Yanli Zhao"

12 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Impact of increased influenza vaccination in 2–3-year-old children on disease burden within the general population: A Bayesian model-based approach

; Yanli Zhao is an employee of MedImmune, the biologics arm of AstraZeneca. Witold Wiecek and Billy Amzal are employees of LASER Analytica who have received funding for the current study from AstraZeneca ... . Vishal Patel is a former employee of LASER Analytica. The funder provided support in the form of salaries for authors Betina Blak, Robert Brody, Judith Hackett, Richard Lawson, Yanli Zhao, and

Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine–purine inversion site of an RNA duplex

RNA duplex regions are often involved in tertiary interactions and protein binding and thus there is great potential in developing ligands that sequence-specifically bind to RNA duplexes. We have developed a convenient synthesis method for a modified peptide nucleic acid (PNA) monomer with a guanidine-modified 5-methyl cytosine base. We demonstrated by gel electrophoresis...

Byproduct-induced in-situ formation of gold colloidal superparticles

supporting data are available in the online version of the paper. Shaojue Wu is currently a fourth-year PhD student under the supervision of Associate Professor Yanli Zhao at Nanyang Technological University ... , Singapore. His research focuses on the preparation and self-assembly of metal nanoparticles for sensing applications. Yanli Zhao is currently an associate professor at Nanyang Technological University

Enhancing Butanol Production under the Stress Environments of Co-Culturing Clostridium acetobutylicum/Saccharomyces cerevisiae Integrated with Exogenous Butyrate Addition

In this study, an efficient acetone-butanol-ethanol (ABE) fermentation strategy integrating Clostridium acetobutylicum/Saccharomyces cerevisiae co-culturing system with exogenous butyrate addition, was proposed and experimentally conducted. In solventogenic phase, by adding 0.2 g-DCW/L-broth viable S. cerevisiae cells and 4.0 g/L-broth concentrated butyrate solution into C...

Brain Correlates of Self-Evaluation Deficits in Schizophrenia: A Combined Functional and Structural MRI Study

Self-evaluation plays an important role in adaptive functioning and is a process that is typically impaired in patients with schizophrenia. Underlying neural mechanisms for this dysfunction may be associated with manifested psychosis. However, the brain substrates underlying this deficit are not well known. The present study used brain blood oxygen level dependent (BOLD...

An efficient protein complex mining algorithm based on Multistage Kernel Extension

Background In recent years, many protein complex mining algorithms, such as classical clique percolation (CPM) method and markov clustering (MCL) algorithm, have developed for protein-protein interaction network. However, most of the available algorithms primarily concentrate on mining dense protein subgraphs as protein complexes, failing to take into account the inherent...

Discrimination of Wild Paris Based on Near Infrared Spectroscopy and High Performance Liquid Chromatography Combined with Multivariate Analysis

Different geographical origins and species of Paris obtained from southwestern China were discriminated by near infrared (NIR) spectroscopy and high performance liquid chromatography (HPLC) combined with multivariate analysis. The NIR parameter settings were scanning (64 times), resolution (4 cm−1), scanning range (10000 cm−1∼4000 cm−1) and parallel collection (3 times). NIR...

Modified nonparametric approaches to detecting differentially expressed genes in replicated microarray experiments

Yanli Zhao 0 Wei Pan 0 0 Division of Biostatistics, School of Public Health, University of Minnesota , MMC 303, A460 Mayo Building, 420 Delaware Street SE, Minneapolis, MN 55455 , USA Motivation: An

Safety and Immunogenicity of Heat-Treated Zoster Vaccine (ZVHT) in Immunocompromised Adults

Background. Safety and immunogenicity of heat-treated zoster vaccine (ZVHT) were assessed in immunocompromised adults. Methods. In a randomized, double-blind, placebo-controlled, multicenter study, 4 doses ZVHT or placebo were administered approximately 30 days apart to adults with either solid tumor malignancy (STM); hematologic malignancy (HM); human immunodeficiency virus (HIV...

Heme Oxygenase-1 Prevents Cardiac Dysfunction in Streptozotocin-Diabetic Mice by Reducing Inflammation, Oxidative Stress, Apoptosis and Enhancing Autophagy

Heme oxygenase-1 (HO-1) has been implicated in cardiac dysfunction, oxidative stress, inflammation, apoptosis and autophagy associated with heart failure, and atherosclerosis, in addition to its recognized role in metabolic syndrome and diabetes. Numerous studies have presented contradictory findings about the role of HO-1 in diabetic cardiomyopathy (DCM). In this study, we...

Varicella-Zoster Virus–Specific Antibody Responses in 50–59-Year-Old Recipients of Zoster Vaccine

Prevaccination and 6-week postvaccination samples from the immunogenicity substudy (n = 2269) of the zoster vaccine (ZV) efficacy trial (N = 22 439) in 50–59-year-old subjects were examined for varicella-zoster virus–specific antibody responses to vaccination. The varicella-zoster virus geometric mean titer (GMT) and geometric mean fold rise were higher in ZV recipients than in...

Efficacy, Safety, and Tolerability of Herpes Zoster Vaccine in Persons Aged 50–59 Years

(See the Editorial Commentary by Li et al, on pages 929–30.) Background. Herpes zoster (HZ) adversely affects individuals aged 50–59, but vaccine efficacy has not been assessed in this population. This study was designed to determine the efficacy, safety, and tolerability of zoster vaccine for preventing HZ in persons aged 50–59 years. Methods. This was a randomized, double-blind...