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Analytical Compliance Modeling of Serial Flexure-Based Compliant Mechanism Under Arbitrary Applied Load

Technology, China, in 1997. His research interests include advanced equipment and parallel kinematic machine. E-mail: . Yao Jiang, born in 1989, is currently a postdoctor at Institute of Instrument Science and

Mensenchymal stem cells can delay radiation-induced crypt death: impact on intestinal CD44+ fragments

Intestinal stem cells are primitive cells found within the intestinal epithelium that play a central role in maintaining epithelial homeostasis through self-renewal and commitment into functional epithelial cells. Several markers are available to identify intestinal stem cells, such as Lgr5, CD24 and EphB2, which can be used to sort intestinal stem cells from mammalian gut. Here, ...

Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth

Invariant natural killer T (iNKT) cells are crucial for host defense against a variety of microbial pathogens, but the underlying mechanisms of iNKT cells activation by microbes are not fully explained. In this study, we investigated the molecular mechanisms of iNKT cell activation in lipopolysaccharide (LPS)-stimulated preterm birth using an adoptive transfer system and diverse ...

Global gene expression patterns of grass carp following compensatory growth

Background Compensatory growth is accelerated compared with normal growth and occurs when growth-limiting conditions are overcome. Most animals, especially fish, are capable of compensatory growth, but the mechanisms remain unclear. Further investigation of the mechanism of compensatory growth in fish is needed to improve feeding efficiency, reduce cost, and explore growth-related ...

Nesfatin-1 Influences the Excitability of Glucosensing Neurons in the Dorsal Vagal Complex and Inhibits Food Intake

Nesfatin-1 is a recently discovered metabolic peptide hormone that decreases food intake after lateral, third, or fourth brain ventricle; cisterna magna; or paraventricular nucleus (PVN) injection in ad libitum fed rats. Additional micro-injection studies will improve the understanding of how nesfatin-1 acts on the brain and define specific nuclei responsive to nesfatin-1, which ...

Transcriptome sequencing of a chimaera reveals coordinated expression of anthocyanin biosynthetic genes mediating yellow formation in herbaceous peony (Paeonia lactiflora Pall.)

Background Herbaceous peony (Paeonia lactiflora Pall.) is a traditional flower in China and a wedding attractive flower in worldwide. In its flower colour, yellow is the rarest which is ten times the price of the other colours. However, the breeding of new yellow P. lactiflora varieties using genetic engineering is severely limited due to the little-known biochemical and molecular ...

Biocompatibility of Mg-Nd-Zn-Zr alloy with rabbit blood

In this study, in vitro blood biocompatibility of Mg-Nd-Zn-Zr (JDBM) alloy was investigated to determine its suitability as a degradable medical biomaterial. Blood biocompatibility was assessed by blood cell aggregation, platelet adhesion, and protein adsorption. A titanium alloy was used as control. The results showed that the JDBM alloy did not induce significant blood cell ...

Nesfatin-1 Stimulates Fatty-Acid Oxidation by Activating AMP-Activated Protein Kinase in STZ-Induced Type 2 Diabetic Mice

Nesfatin-1 is an anorexigenic peptide involved in energy homeostasis. Recently, nesfatin-1 was reported to decrease blood glucose level and improve insulin sensitivity in high-fat diet-fed rats. However, little information is known about the influence of nesfatin-1 on lipid metabolism either in physiological or diabetic condition. This study undertook whether nesfatin-1 was ...

In vitro degradation and biocompatibility of Mg-Nd-Zn-Zr alloy

In this study, in vitro degradation and biocompatibility of Mg-Nd-Zn-Zr (NZK) alloy were investigated to determine its suitability as a degradable medical biomaterial. Its corrosion properties were evaluated by static immersion test, electrochemical corrosion test, scanning electron microscopy (SEM), and energy dispersive spectroscopic (EDS) analysis, and in vitro ...

An Arabidopsis thaliana (Ler) inbred line AFDL exhibiting abnormal flower development mainly caused by reduced AP1 expression

The genetic network controlling flowering and flower development consists of a set of floral integrator genes that play a role in light sensing, hormone signaling and developmental pathways. These integrators activate the expression of meristem identity genes LEAFY (LFY) and APETALA1 (AP1) to initiate the flowering transition. However, how the expression of key genes, such as AP1, ...