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Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line

Glioblastoma is the most common and aggressive brain tumor associated with a poor prognosis. Plant homeodomain finger protein 20 (PHF20) is highly expressed in primary human gliomas and its expression is associated with tumor grade. However, the molecular mechanism by which PHF20 regulates glioblastoma remains poorly understood. Genome wide gene expression analysis was performed to ...

Prenatal exposure to the Great Chinese Famine and mid-age hypertension

Background One of the most terrible famines last century was Great Chinese Famine (GCF) in 1959~1961 when millions of people died from starving. Under-nutrition during famine between the Western and Eastern (Dutch Hungry vs. GCF) was similar, while cardiovascular consequences might not be the same. Addressing such questions may gain new insight into prevention of cardiovascular ...

Molecular dynamics simulation and bioinformatics study on chloroplast stromal ridge complex from rice (Oryza sativa L.)

Background Rice (Oryza sativa L.) is one of the most important cereal crops in the world and its yield is closely related to the photosynthesis efficiency. The chloroplast stromal ridge complex consisting of PsaC-PsaD-PsaE plays an important role in plant photosynthesis, which has been a subject of many studies. Till now, the recognition mechanism between PsaC and PsaD in rice is ...

Formulation and Drug Loading Features of Nano-Erythrocytes

Nano erythrocyte ghosts have recently been used as drug carriers of water-soluble APIs due to inherit biological characteristics of good compatibility, low toxicity, and small side-effect. In this study, we developed a novel drug delivery system based on nano erythrocyte ghosts (STS-Nano-RBCs) to transport Sodium Tanshinone IIA sulfonate (STS) for intravenous use in rat. ...

Electron transport layer driven to improve the open-circuit voltage of CH3NH3PbI3 planar perovskite solar cells

Suitable electron transport layers are essential for high performance planar perovskite heterojunction solar cells. Here, we use ZnO electron transport layer sputtered under oxygen-rich atmosphere at room temperature to decrease the hydroxide and then suppress decomposition of perovskite films. The perovskite films with improved crystallinity and morphology are achieved. Besides, ...

Small RNA and degradome profiling reveals miRNA regulation in the seed germination of ancient eudicot Nelumbo nucifera

Ding 0 0 State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University , Wuhan 430072 , China 1 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology

Electronic Structure and Carrier Mobilities of Arsenene and Antimonene Nanoribbons: A First-Principle Study

Arsenene and antimonene, i.e. two-dimensional (2D) As and Sb monolayers, are the recently proposed cousins of phosphorene (Angew. Chem. Int. Ed., 54, 3112 (2015)). Through first-principle calculations, we systematically investigate electronic and transport properties of the corresponding As and Sb nanoribbons, which are cut from the arsenene and antimonene nanosheets. We find that ...

Comparative transcript profiling of alloplasmic male-sterile lines revealed altered gene expression related to pollen development in rice (Oryza sativa L.)

Background Cytoplasmic male sterility (CMS) is an ideal model for investigating the mitochondrial-nuclear interaction and down-regulated genes in CMS lines which might be the candidate genes for pollen development in rice. In this study, a set of rice alloplasmic sporophytic CMS lines was obtained by successive backcrossing of Meixiang B, with three different cytoplasmic types: ...

Filling and unfilling carbon capsules with transition metal oxide nanoparticles for Li-ion hybrid supercapacitors: towards hundred grade energy density

Zhen Gao 1 Yi Ding 1 0 Key Laboratory of Advanced Energy Materials Chemistry (MOE), College of Chemistry, Nankai University , Tianjin 300071 , China 1 Tianjin Key Laboratory of Advanced Functional

Unusual structural and electronic properties of porous silicene and germanene: insights from first-principles calculations

Using first-principles calculations, we investigate the geometric structures and electronic properties of porous silicene and germanene nanosheets, which are the Si and Ge analogues of α−graphyne (referred to as silicyne and germanyne). It is found that the elemental silicyne and germanyne sheets are energetically unfavourable. However, after the C-substitution, the hybrid ...

Guest editorial: special issue on risk evaluation and management for future electric power systems

, Copenhagen, Denmark (&) 1 Yi Ding (Ph.D.) Associate Professor Technical University of Denmark Copenhagen , Denmark July 25, 2013 - Providing a reliable and economical supply of electricity to customers has ... for conducting contingency analysis (CA) during real-time power system operations, which can speed up the computation time through high performance computing. Yi Ding, Weixiang Shen et al utilize the

Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice

Acetaminophen (APAP) overdose is the most frequent cause of drug-induced acute liver failure. The purpose of this study was to investigate whether paeonol protected against APAP-induced hepatotoxicity. Mice treated with paeonol (25, 50, 100 mg/kg) received 400 mg/kg acetaminophen intraperitoneally (i.p.) and hepatotoxicity was assessed. Pre-treatment with paeonol for 6 and 24 h ...

Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area

Background Brain-derived neurotrophic factor (BDNF) has been implicated in cognitive performance and the modulation of several metabolic parameters in some disease models, but its potential roles in successful aging remain unclear. We herein sought to define the putative correlation between BDNF Val66Met and several metabolic risk factors including BMI, blood pressure, fasting ...

Inequality trends of health workforce in different stages of medical system reform (1985-2011) in China

competing interests. Authors’ contributions Kaiyuan Zhou participated in the design of the study, performed the statistical analysis, and drafted the manuscript. Xinyi Zhang and Yi Ding participated in the

Genome-Wide Identification of SSR and SNP Markers Based on Whole-Genome Re-Sequencing of a Thailand Wild Sacred Lotus (Nelumbo nucifera)

Genomic resources such as single nucleotide polymorphism (SNPs), insertions and deletions (InDels) and SSRs (simple sequence repeats) are essential for crop improvement and better utilization in genetic breeding. However, the resources for the sacred lotus (Nelumbo nucifera Gaertn.) are still limited. In the present study, to dissect large-scale genomic molecular marker resources ...

Genome-wide analysis of DNA methylation in photoperiod- and thermo-sensitive male sterile rice Peiai 64S

Background Epigenetic modifications play important roles in the regulation of plant development. DNA methylation is an important epigenetic modification that dynamically regulates gene expression during developmental processes. However, little studies have been reported about the methylation profiles of photoperiod- and thermo-sensitive genic male sterile (PTGMS) rice during the ...

Uncertainty-averse TRANSCO planning for accommodating renewable energy in CO2 reduction environment

interests include power systems planning and power market innovation. Yi DING received the B.Eng. degree from Shanghai Jiaotong University, China, and the Ph.D. degree from Nanyang Technological University

Guizhi-Shaoyao-Zhimu decoction attenuates rheumatoid arthritis partially by reversing inflammation-immune system imbalance

Background Guizhi-Shaoyao-Zhimu decoction (GSZD) has been extensively used for rheumatoid arthritis (RA) therapy. Marked therapeutic efficacy of GSZD acting on RA has been demonstrated in several long-term clinical trials without any significant side effects. However, its pharmacological mechanisms remain unclear due to a lack of appropriate scientific methodology. Methods GSZD’s ...

Operational reliability evaluation of restructured power systems with wind power penetration utilizing reliability network equivalent and time-sequential simulation approaches

) and the source are credited. Yi DING received the B.Eng. degree from Shanghai Jiaotong University, China, and the Ph.D. degree from Nanyang Technological University (NTU), Singapore, both in electrical