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The Regulation of cGAS

The cGAS-MITA pathway of cytosolic DNA sensing plays essential roles in immune response against pathogens that contain DNA or with DNA production in their life cycles. The cGAS-MITA pathway also detects leaked or aberrant accumulated self DNA in the cytoplasm under certain pathological conditions, such as virus induced cell death, DNA damage, mitochondria damage, gene mutations...

The Strategy of Inverter Seamless Mode Switching in Master-Slave Independent Micro-grid

In order to realize the uninterruptible power supply in the master-slave independent micro-grid system, the micro-grid inverter needs to realize the mode switching of the grid-connection/grid-disconnection. How to reduce the transient oscillation during switching, so as to effectively achieve seamless mode switching is a key issue to be solved. In this paper, a typical master...

Urothelial MaxiK-activity regulates mucosal and detrusor metabolism

Contributions Conceptualization: Kelvin P. Davies. Data curation: Yi Wang, Kelvin P. Davies. Formal analysis: Yi Wang, Kelvin P. Davies. Funding acquisition: Yi Wang, Kelvin P. Davies. Investigation: Yi Wang ... , Kelvin P. Davies. Methodology: Yi Wang, Kelvin P. Davies. Project administration: Kelvin P. Davies. Supervision: Kelvin P. Davies. Visualization: Kelvin P. Davies. Writing ± original draft: Yi Wang

A study of expertise effects for products with contradictory semantics

In the design studies, researchers often use the semantic differential method with bipolar adjectives, such as “modern vs. classical” or “simple vs. complex” when investigating the semantics projected by product forms. However, in design practice, some design examples clearly exhibit the simultaneous use of contradictory meanings in product semantics. For example, retro car...

Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus

curation: Mei-Zhou Huang, Dong-An Cui, Xiao-Jun Kong. Formal analysis: Mei-Zhou Huang. Funding acquisition: Jian-Yong Li. Investigation: Sheng-Yi Wang. Methodology: Mei-Zhou Huang, Xi-Wang Liu. Project ... administration: Mei-Zhou Huang, Jian-Yong Li. Resources: Sheng-Yi Wang, Jian-Yong Li. Software: Xi-Wang Liu. Supervision: Mei-Zhou Huang, Dong-An Cui, Jian-Yong Li. Validation: Hui Wang, Jian-Yong Li

Correction: An evolutionarily stable strategy and the critical point of hog futures trading entities based on replicator dynamic theory: 2006-2015 data for China's 22 provinces

Ling-Fei Deng Gang-Yi Wang All of the authors' names are spelled incorrectly. The correct author list is: Jin-Bo Pang, Lingevolutionarily stable strategy and the critical point of hog futures trading

Standard Model mass spectrum in inflationary universe

We work out the Standard Model (SM) mass spectrum during inflation with quantum corrections, and explore its observable consequences in the squeezed limit of non-Gaussianity. Both non-Higgs and Higgs inflation models are studied in detail. We also illustrate how some inflationary loop diagrams can be computed neatly by Wick-rotating the inflation background to Euclidean signature...

Targeted release of stromal cell-derived factor-1α by reactive oxygen species-sensitive nanoparticles results in bone marrow stromal cell chemotaxis and homing, and repair of vascular injury caused by electrical burns

-Wei Deng for their experimental technical assistance. Author Contributions Conceptualization: Zhi-Bao Huo, Guang-Yi Wang, Zhao-Fan Xia. Formal analysis: Fang He, Peng-Fei Luo, Tao Tang. Funding ... acquisition: Guang-Yi Wang. Investigation: Fang He, Peng-Fei Luo, Tao Tang, Fang Zhang, He Fang, Shi-Zhao Ji. Methodology: Fang He, Peng-Fei Luo, Tao Tang, Yu Sun, Guo-Sheng Wu, Bo-Han Pan. Project

16S rRNA analysis of diversity of manure microbial community in dairy farm environment

sample collection. Author Contributions Conceptualization: Pramod Pandey, Richard Jeannotte. Data curation: Pramod Pandey, Colleen Chiu, Max Miao, Yi Wang, Matthew Settles, Noelia Formal analysis ... : Pramod Pandey, Colleen Chiu, Max Miao, Yi Wang, Richard Pereira, Rich Funding acquisition: Pramod Pandey. Investigation: Pramod Pandey, Colleen Chiu, Richard Jeannotte. Methodology: Pramod Pandey

Reference equations for the six-minute walk distance in the healthy Chinese population aged 18–59 years

Conceptualization: He Zou, Xiaoshu Chen. Data curation: He Zou. Formal analysis: He Zou, Jia Zhang, Yi Wang. Investigation: He Zou, Xiuruo Zhu, Xiaozhen Wu, Fang Liu, Xiaofeng Xie. Methodology: He Zou, Xiaoshu ... Chen. Project administration: He Zou, Xiaoshu Chen. Resources: He Zou, Xiuruo Zhu. Supervision: He Zou, Xiuruo Zhu, Yi Wang, Xiaoshu Chen. Validation: He Zou, Xiaoshu Chen. Writing ± original draft

Hand tool handle design based on hand measurements

This study provides a tool handle design guideline based on measurements of hand gripping diameter. Anthropometric measurements on hands of 60 participants were collected with a caliper. The results in the current study concluded the guidelines for handle design, including: (1) a definition of handle design was depended on the users’ hand length and hand breadth, (2) different...

Design and Implementation of the Automatic Assessment System for the Command and Control Specialty in Ships

On the basis of analyzing the actual demand of automated assessment system for the command and control specialty in ships, the thought of the overall design of automated assessment system for the command and control specialty in ships is given, and the concrete realization methods of the user login module, test paper operation module and system maintenance module are studied and...

The ethylene response factor AtERF4 negatively regulates the iron deficiency response in Arabidopsis thaliana

administration: Yi Wang. Software: Xinzhong Zhang, Xuefeng Xu, Zhenhai Han. Writing ± original draft: Wei Liu, N. J. Umuhoza Karemera, Yi Wang. 18 / 22 19 / 22 20 / 22 21 / 22 1. Briat JF , Fobis-Loisy I

Investigating spousal concordance of diabetes through statistical analysis and data mining

Health Research Institutes for providing the NHIRD. 12 / 16 Author Contributions Conceptualization: Jong-Yi Wang. Data curation: Jong-Yi Wang, Ya-Tun Yang. Formal analysis: Ya-Tun Yang. Funding ... acquisition: Jong-Yi Wang. Methodology: Jong-Yi Wang. Project administration: Jong-Yi Wang. Resources: Jong-Yi Wang. Software: Ya-Tun Yang. Validation: Chiu-Shong Liu, Chi-Hsuan Lung. Writing ± original

Chitosan Nanolayered Cisplatin-Loaded Lipid Nanoparticles for Enhanced Anticancer Efficacy in Cervical Cancer

In this study, cisplatin (CDDP)-loaded chitosan-coated solid lipid nanoparticles (SLN) was successfully formulated to treat HeLa cervical carcinoma. The formulation nanoparticles were nanosized and exhibited a controlled release of drug in physiological conditions. The blank nanoparticles exhibited an excellent biocompatibility profile indicating its suitability for cancer...

Identification and validation of reference genes for gene expression analysis in Aphidius gifuensis (Hymenoptera: Aphidiidae)

. Validation: Xue-Ke Gao, Shuai Zhang, Jun-Yu Luo, Li-Min LuÈ, Jin-Jie Cui. Writing ± original draft: Xue-Ke Gao, Jin-Jie Cui. Writing ± review & editing: Xue-Ke Gao, Shuai Zhang, Jun-Yu Luo, Chun-Yi Wang, Li

Functional differentiation and spatial-temporal co-expression networks of the NBS-encoding gene family in Jilin ginseng, Panax ginseng C.A. Meyer

Conceptualization: Yi Wang, Meiping Zhang. Data curation: Rui Yin, Mingzhu Zhao, Kangyu Wang, Meiping Zhang. Formal analysis: Rui Yin, Mingzhu Zhao, Meiping Zhang. Funding acquisition: Yi Wang, Meiping Zhang ... . Investigation: Rui Yin, Mingzhu Zhao, Kangyu Wang, Yanping Lin, Yanfang Wang, Chunyu Sun, Yi Wang, Meiping Zhang. Methodology: Rui Yin, Mingzhu Zhao, Meiping Zhang. Project administration: Yi Wang, Meiping

Heavily Graphitic-Nitrogen Self-doped High-porosity Carbon for the Electrocatalysis of Oxygen Reduction Reaction

Large-scale production of active and stable porous carbon catalysts for oxygen reduction reaction (ORR) from protein-rich biomass became a hot topic in fuel cell technology. Here, we report a facile strategy for synthesis of nitrogen-doped porous nanocarbons by means of a simple two-step pyrolysis process combined with the activation of zinc chloride and acid-treatment process...

HA117 endows HL60 cells with a stem-like signature by inhibiting the degradation of DNMT1 via its ability to down-regulate expression of the GGL domain of RGS6

All-trans retinoic acid (ATRA) induces complete remission in almost all patients with acute promyelocytic leukemia (APL) via its ability to induce the in vivo differentiation of APL blasts. However, prolonged ATRA treatment can result in drug resistance. In previous studies, we generated a multi-drug-resistant HL60/ATRA cell line and found it to contain a new drug resistance...