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Trends of Visual Impairment and Blindness in the Singapore Chinese Population over a Decade

this work. AffiliationsSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, SingaporeYih-Chung Tham, Sing-Hui Lim, Yuan Shi, Miao-Li Chee, Ying Feng Zheng, Jacqueline Chua, Seang ... -Li Chee in:Nature Research journals • PubMed • Google Scholar Search for Ying Feng Zheng in:Nature Research journals • PubMed • Google Scholar Search for Jacqueline Chua in:Nature Research journals

Fuzzy Sliding Mode Control for the Vehicle Height and Leveling Adjustment System of an Electronic Air Suspension

interests include elec‑ tronically controlled air suspension and engineering application of advanced control theory. E‑mail: YingFeng Cai, born in 1985, is currently an associate professor and a master ... Springer Nature remains neutral with regard to jurisdictional claims in pub‑ lished maps and institutional affiliations. [1] Xiao‑ Qiang Sun , YingFeng Cai , Shao ‑Hua Wang , et al. A hybrid approach to

Macrophage colony-stimulating factor (M-CSF) is an intermediate in the process of luteinizing hormone-induced decrease in natriuretic peptide receptor 2 (NPR2) and resumption of oocyte meiosis

Luteinizing hormone (LH) regulation of the ligand, natriuretic peptide precursor type C, and its receptor, natriuretic peptide receptor 2 (NPR2), is critical for oocyte maturation; however, the mechanism is not fully understood. Macrophage colony-stimulating factor (M-CSF) has recently been shown to be involved in oocyte maturation and ovulation. In the present study we...

Characterization of the complete chloroplast genome of the Chinese cherry Prunus pseudocerasus (Rosaceae)

The Chinese cherry Prunus pseudocerasus is a fruit tree species with high economic and ornamental values. Many of its wild populations are under threat or even on the verge of extinction. Here, its complete chloroplast genome was assembled using next-generation sequencing technology. The circular genome is 157,834 bp long, and contains a pair of inverted repeat (IR) regions of 26...

CD106 is a novel mediator of bone marrow mesenchymal stem cells via NF-κB in the bone marrow failure of acquired aplastic anemia

Background Acquired aplastic anemia (AA) is characterized by deficiency or dysfunction of the bone marrow (BM) microenvironment. However, little is known about the impairment of BM-derived mesenchymal stem cells (MSCs) in AA patients. Methods We used Illumina HiSeqTM 2000 sequencing, quantitative real-time polymerase chain reaction (qRT-PCR), flow cytometry (FCM), and Western...

Intrathecal magnesium sulfate does not reduce the ED 50 of intrathecal hyperbaric bupivacaine for cesarean delivery in healthy parturients: a prospective, double blinded, randomized dose-response trial using the sequential allocation method

Background Addition of intrathecal magnesium sulfate to local anesthetics has been reported to potentiate spinal anesthesia and prolong analgesia in parturients. The current study was to determine whether intrathecal magnesium sulfate would reduce the dose of hyperbaric bupivacaine in spinal anesthesia with bupivacaine and sufentanil for cesarean delivery. Methods Sixty healthy...

Study of Rayleigh-backscattering induced coherence collapse in an asymmetric DFB FL sensor

Citation: Wen LIU, Lina MA, Zhengliang HU, Ying FENG, and Huayong YANG, “Study of Rayleigh-Backscattering Induced Coherence Collapse in an Asymmetric DFB FL Sensor,” Photonic Sensors Study of

The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort

The methylation status of O-6-methylguanine-DNA methyltransferase (MGMT) is associated with the prognosis in gliomas and in other cancers. Recent studies showed that rs16906252, an SNP in the MGMT promoter, is associated with promoter methylation and is a predictor of the overall survival time (OST) and the response to temozolomide (TMZ) treatment. However, these findings haven’t...

Consequences of orthodontic treatment in malocclusion patients: clinical and microbial effects in adults and children

Background Malocclusion is a common disease of oral and maxillofacial region. The study was aimed to investigate levels changes of periodontal pathogens in malocclusion patients before, during and after orthodontic treatments, and to confirm the difference between adults and children. Method One hundred and eight malocclusion patients (46 adults and 62 children at the school-age...

Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma

Background The purpose of this study was to develop an effective nomogram capable of estimating the individual survival outcomes of patients with hepatocellular carcinoma (HCC), and compare the predictive accuracy and discriminative ability with other staging systems. Methods The nomogram was established based on a retrospective study of 661 patients newly diagnosed with HCC at...

Orchid Species Richness along Elevational and Environmental Gradients in Yunnan, China

The family Orchidaceae is not only one of the most diverse families of flowering plants, but also one of the most endangered plant taxa. Therefore, understanding how its species richness varies along geographical and environmental gradients is essential for conservation efforts. However, such knowledge is rarely available, especially on a large scale. We used a database extracted...

1,3-Bis(2-chloroethyl)-1-nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance–fluorescence imaging for tracking of chemotherapeutic agents

Chiung-Yin Huang,1 Chen-Chi M Ma,3 Ju-Yu Chen,1 Li-Ying Feng,1 Hung-Wei Yang2 1Department of Neurosurgery, Chang Gung Memorial Hospital, School of Medicine, Chang Gung University, Taoyuan, 2Institute of

Effects of albendazole combined with TSII-A (a Chinese herb compound) on optic neuritis caused by Angiostrongylus cantonensis in BALB/c mice

Background Angiostrongylus cantonensis (A. cantonensis) infection can lead to optic neuritis, retinal inflammation, damage to ganglion cells, demyelination of optic nerve and visual impairment. Combined therapy of albendazole and dexamethasone is a common treatment for the disease in the clinic, but it plays no role in vision recovery. Therefore, it has been necessary to explore...

Complete sequence and gene organization of the mitochondrial genome of Batocera lineolata Chevrolat (Coleoptera: Cerambycidae)

Batocera lineolata Chevrolat, 1852 is an important forest pest that is found mainly in China, Vietnam, India, and Japan. The complete mitochondrial genome (mitogenome) sequence of B. lineolata was determined by long polymerase chain reaction (PCR) and conserved primer walking approaches. The results showed that the entire mitogenome is 15418 bp long with 74.48% A+T content. The...

Enhanced optical confinement and lasing characteristics of individual urchin-like ZnO microstructures prepared by oxidation of metallic Zn

We prepared urchin-like micron-sized ZnO cavities with high optical quality by oxidizing metallic Zn and proposed the mechanism that resulted in the growth of the urchin-like microstructures. The photoluminescence spectra of the ZnO microstructures had a predominant excitonic emission at room temperature. The lasing properties of the urchin-like ZnO microstructures were...

The Endophytic Bacterium, Sphingomonas SaMR12, Improves the Potential for Zinc Phytoremediation by Its Host, Sedum alfredii

The endophytic bacterium, Sphingomonas SaMR12, isolated from Sedum alfredii Hance, appears to increase plant biomass and zinc-extraction from contaminated soil; however, the mechanism by which this occurs is not clear. Here, the ability of SaMR12 to promote zinc extraction and its effects on root morphology and exudation were examined in hydroponics. Zinc treatment increased...

Prognostic significance of PD-L1 expression in patients with gastric cancer in East Asia: a meta-analysis

Wang, Rui-Jie Yang, Ying-Ying Feng, She-Gan Gao, Xiao-Shan Feng Department of Oncology, Cancer Institute, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, People’s

Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer

Small cell lung cancer (SCLC) is an aggressive malignancy with limited treatment options. We previously found that PARP is overexpressed in SCLC and that targeting PARP reduces cell line and tumor growth in preclinical models. However, SCLC cell lines with PI3K/mTOR pathway activation were relatively less sensitive to PARP inhibition. In this study, we investigated the proteomic...

Rapamycin Inhibition of Polyposis and Progression to Dysplasia in a Mouse Model

Familial adenomatous polyposis (FAP) is often due to adenomatous polyposis coli (APC) gene germline mutations. Somatic APC defects are found in about 80% of colorectal cancers (CRCs) and adenomas. Rapamycin inhibits mammalian target of rapamycin (mTOR) protein, which is often expressed in human adenomas and CRCs. We sought to assess the effects of rapamycin in a mouse polyposis...